Sentences with phrase «express hematopoietic»

MSC do not express hematopoietic markers, but a specific pattern of molecules, such as SH2 (CD105), SH3, SH4 (CD73) and STRO - 1.

Not exact matches

They also expressed lower levels of an RNA message that controls the expression of a family of proteins called SOC, known to inhibit the migration of hematopoietic stem cells.

It is caused by mutations in the gene encoding the WAS protein (WASp) expressed in hematopoietic cells.

There are no specific markers to identify them; however, they are negative for hematopoietic cell markers like CD34 / 45 / HLA - DR and express CD90 / 73/105 on their surface 2, 3, 4.

The chemokine receptor CXCR - 4 is expressed on CD34 + hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell - derived factor - 1.

This gave a mixed population of cells with 20 % expressing CD34, a hematopoietic stem cell marker, with some co-expression of endothelial cell markers (CD31, Flk1, and VE - cadherin).

Under normal physiological conditions, CXCR4 is mainly expressed in the hematopoietic and immune systems (Figure 1), where it carries out multiple functions.

Hematopoietic stem cells express the markers CD34 and CD133 and can repopulate a myeloablated recipient after allogeneic or autologous transplantation.

A major scientific puzzle, said Singh, has been how and why immature hematopoietic stem cells initially express genes that are characteristic of more than one cell lineage.

Importantly, these cells expressed CD45, with smaller subpopulations expressing the important hematopoietic markers CD117 and Sca - 1, suggesting that these cells may have the potential to populate bone marrow and eventually replenish senescent peripheral blood hematopoietic cells.

In this medium, the HOXB4 gene is activated and stoichiometrically expressed at a 1 ∶ 1 ratio with GFP, so that the cells turn green as they become hematopoietic.

TNFR1 is expressed on most cell types, while TNFR2 expression is restricted to endothelial, hematopoietic and some neuronal populations [37], [38].

Because Syk is expressed in many kinds of hematopoietic lineage cells and involved in various ITAM - mediated signal transduction pathways (45), our current finding that RhoH facilitates Syk activation will shed new light on ITAM - based immune responses.