Sentences with phrase «expressed by immune cells»

Not exact matches

«We found that a protein expressed by gut bacteria called Bacteroides works to prevent IBD by rapidly recruiting white blood cells to kill a cell of the immune system that is responsible for orchestrating IBD,» says McCoy.

CRH, in turn, triggered production of the cell surface protein FasL; trophoblasts expressing FasL then form a protective shield of sorts around the embryo by forcing any attacking immune cells to self - destruct.

S. mansoni IPSE binds to Immunoglobulin E (IgE), an antibody produced by the immune system that is expressed on the surface of basophils, a type of immune cell; and mast cells, another immune cell that mediates inflammation; and sequesters chemokines, signaling proteins that alert white cells to infection sites.

Two types of vaccines were used for the study: one constructed with genetically engineered DNA molecules that teach immune system cells to recognize premalignant cells expressing HPV16 E7 proteins, and one that is a non-infectious, engineered virus that targets and kills precancerous cells marked by HPV16 and HPV18 E6 and E7 proteins.

Tumor cells develop mechanisms to evade detection by the immune system by expressing a protein called PD - L1.

«Brain cancer cells are very good at evading the host immune system, because they do not express specific targets that can be recognized by immune cells,» said Liau, professor and vice chair of neurosurgery.

Some of our next steps are to determine the biological process that causes cancer cells to express non-mutated, shared antigens, and the means by which dormant metastases escape immune elimination.

This suggests that Vanin - 1 expressed by epithelial cells exerts a control on immune responses.

The approach developed by the MGH team starts with the engineered protein, which in this case fuses an antibody fragment targeting a protein called mesothelin — expressed on the surface of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a protein from the tuberculosis bacteria that stimulates the activity of dendritic and other immune cells.

Induction of immune responses in patients with b - cell lymphoma against the surface - immunoglobulin idiotype expressed by their tumors