«Almost all of the animals that were vaccinated survived, including mice that were challenged with viruses that
expressed hemagglutinin subtypes that were not in the vaccine at all, viruses that expressed H2, H6, H10, and H11,» said Dr. Taubenberger.
Not exact matches
In the new study, researchers at the NIAID used a virus - like particle vaccine cocktail that
expressed a handful of different subtypes of a key surface protein of the influenza virus:
hemagglutinin H1, H3, H5 and H7.
The vaccines deliver mRNA encoding for
hemagglutinin to the body's cells, directing them to produce and
express this viral antigenic protein transiently on the cell's surface, much like a native infection would do, but without the ability to cause disease.
They
expressed two versions of
hemagglutinin — one adapted to eggs and one adapted to humans — on one virus particle.