Sentences with phrase «expressed in a given cell»

The pattern of which genes are expressed in a given cell is what distinguishes a neuron from, say, a liver cell.

Not exact matches

A large body of research has reported that Nanog is allelically regulated — that is, only one copy of the gene is expressed at any given time — and fluctuations in its expression are responsible for the differences seen in individual embryonic stem (ES) cells» predilection to differentiate into more specialized cells.

The widely accepted RNA - world theory posits that RNA — the molecule that today plays roles in coding, regulating, and expressing genes — elevated itself from the primordial soup of amino acids and cosmic chemicals, eventually to give rise first to short proteins called peptides and then to single - celled organisms.

In the study, Stephen Maricich and colleagues identified a subpopulation of Atoh1 - expressing cells in hair and whisker follicles within mouse skin that exclusively give rise to Merkel cells during development and adulthooIn the study, Stephen Maricich and colleagues identified a subpopulation of Atoh1 - expressing cells in hair and whisker follicles within mouse skin that exclusively give rise to Merkel cells during development and adulthooin hair and whisker follicles within mouse skin that exclusively give rise to Merkel cells during development and adulthood.

Glioblastoma cells do not naturally produce NY - ESO - 1, so the drug decitabine is given prior to injecting the NY - ESO - 1 targeting T cells in order to cause the tumor cells to express the NY - ESO - 1 target.

When Lin engineered the telomerase - expressing hepatocytes to die in response to a chemical signal and gave the mice with a liver - damaging chemical, he found that those animals in which the telomerase cells had been killed exhibited much more severe liver scarring than those in which the cells were functional.

However, this is unlikely given that the frequency of in - frame mutations remained stable over nearly four weeks in culture, that there was no significant increase in cell death between control cultures and those treated with X4 - ZFNs, and that the most common in - frame mutant was not expressed on the cell surface and thus can not maintain functionality.

Chromatin structure plays an important role in regulating what genes are created, or expressed, in a given cell.

After implanting the tumor, they gave the mice a drug to trigger the tumor cells to express the aquaporin reporter gene, which made the tumor look darker in MRI images.

Positive clones were then differentiated using defined serum - free conditions outlined in Ng, et al [7], which overall gave rise to a CD45 + CD56 + CD117 − CD94 + population of cytotoxic NK cells [8] expressing the CD4 construct and other surface markers in a similar manner to peripheral blood NK cells.

g defined serum - free conditions outlined in Ng, et al [7], which overall gave rise to a CD45 + CD56 + CD117 − CD94 + population of cytotoxic NK cells [8] expressing the CD4 construct and other surface markers in a similar manner to peripheral blood NK cells.

Consequently only a small proportion of cells in each epithelium express any given receptor, which makes their detection challenging.