Myriad control switches help to arbitrate how genes get
expressed in different cells and tissues, and those switches are often triggered by maternal diet, toxic exposures and many other environmental factors.
All cells in the human body contain these bases in exactly the same order, but different genes are
expressed in different cell types, allowing them to carry out their specialized functions.
Not exact matches
The scientists also generated a panel of (reconstructed) ancestral and existing TRIM5 genes (19 total),
expressed them
in cultured
cell lines, and exposed the
cells to 16
different retroviruses (lentiviruses and others) to see which TRIM5 versions conferred resistance to which viruses.
Since genes for the T -
cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families
expressed and rearranged
in T
cells are located on
different chromosomes, just as are the B -
cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.
Each
cell expresses a
different color, allowing researchers to trace connections
in the fish's neural network.
«It is possible that the
cells that might
express or respond to Ctgf are
different in this context.
«The views that are
expressed there are very much
different from researchers
in stem
cell work and reproductive medicine.»
However, two types of
cells in the olfactory epithelium (specialized tissue responsible for sense of smell), are mixed together and form a mosaic pattern despite
expressing different types of cadherins.
Already, we see that
cells from people with bipolar disorder are
different in how often they
express certain genes, how they differentiate into neurons, how they communicate, and how they respond to lithium,» says Sue O'Shea, Ph.D., the experienced U-M stem
cell specialist who co-led the work.
HDAC3 functions on the epigenome, the molecular component of the
cell nucleus that specifies which genes are
expressed — and just as importantly, which ones are not —
in different cells of the body.
Wellcome Trust Sanger Institute scientists and their collaborators have developed a new analysis tool that was able to show, for the first time, which genes were
expressed by individual
cells in different genetic versions of a benign blood cancer.
They found that the number of copies of lncRNA genes on a chromosome consistently change
in 12
different cancer types and lncRNA genes are widely
expressed in cancer
cells.
To visualize
different cell types
in the brain, researchers often need genetic access to that
cell — the ability to
express a gene of interest only
in, say, chandelier
cells, but not neighboring neurons.
In a paper published earlier this year in Molecular Cell, he and his team explored the activity of the FOS / JUN protein complex, which is expressed across many different cell types in the brain but appears to regulate unique programs in each different cell typ
In a paper published earlier this year
in Molecular Cell, he and his team explored the activity of the FOS / JUN protein complex, which is expressed across many different cell types in the brain but appears to regulate unique programs in each different cell typ
in Molecular
Cell, he and his team explored the activity of the FOS / JUN protein complex, which is expressed across many different cell types in the brain but appears to regulate unique programs in each different cell t
Cell, he and his team explored the activity of the FOS / JUN protein complex, which is
expressed across many
different cell types in the brain but appears to regulate unique programs in each different cell t
cell types
in the brain but appears to regulate unique programs in each different cell typ
in the brain but appears to regulate unique programs
in each different cell typ
in each
different cell t
cell type.
Lastly, the team identified a gene, calretinin,
in the hippocampal
cells which was not
expressed in the neocortical
cells — suggesting the possibility that these
cells exhibit
different functional properties as well.
While it is present on a number of
different types of
cells in the body, it is
expressed at higher levels on metastatic tumour
cells, including those which have spread from the lung.
The team immersed the stem
cells in four
different types of these cultures and analysed which genes they
expressed in which environment, and to what extent.
Cells in five different organs had died and other cells were expressing proteins associated with radiation respo
Cells in five
different organs had died and other
cells were expressing proteins associated with radiation respo
cells were
expressing proteins associated with radiation responses.
Neuronal
cells express a pp60c - src variant that displays an altered electrophoretic mobility and a
different V8 peptide pattern relative to pp60c - src
expressed in tissues of non-neuronal origin.
The selection strategy targeted
cell populations
expressing the inducible endothelial
cell adhesion molecules, E-selectin and VCAM - 1, and proved successful
in generating microvascular endothelial
cell lines from a number of
different organs.
But of course, posed this way the question does not distinguish between stem
cells obtained
in different ways (and indeed it is sensible to assume that those who
expressed opposition
in response to this question believed they were being asked about embryonic stem
cells, although the survey does not allow us to know that with confidence).
This can come
in many
different aspects, misfolded proteins located
in the
cell,
expressed too much or too little
cell functional defects, premature death when put
in proliferation, etc..
Transcription factors are
expressed (or made) at
different levels
in different cell types, and control what genes are
expressed in every
cell, making sure, for example, that a liver
cell remains a liver
cell and does not become a neuron.
Instead, they discovered that each V. carteri
cell type
expresses orthologs of genes from
different temporal phases of the light — dark cycle
in a related unicellular alga, Chlamydomonas reinhardtii, with somatic
cells enriched for expression of dark - phase genes, and gonidial
cells enriched for expression of light - phase genes.
cell type
expresses orthologs of genes from
different temporal phases of the light — dark cycle
in a related unicellular alga,
We learn which specific genes are
expressed in cancer
cells and how a patient may respond to
different therapies, so that we can select the most appropriate targeted treatment for the particular cancer.
Timelapse of the internalisation of a chimeric doublet of
cells expressing an actin marker (LifeAct)
in different colours (snapshots taken every 15 min)
One common analysis applied to scRNA - seq data involves detecting differentially
expressed (DE) genes between
cells in different biological groups.
«U.N.I (You And I)» from And the Winner Isn't «Love and Lies» from Band Aid «If I Dare» from Battle of the Sexes «Evermore» from Beauty and the Beast «How Does a Moment Last Forever» from Beauty and the Beast «Now or Never» from Bloodline: Now or Never «She» from Bombshell: The Hedy Lamarr Story «Your Hand I Will Never Let It Go» from The Book of Henry «Buddy's Business» from Brawl
in Cell Block 99 «The Crown Sleeps» from The Breadwinner «World Gone Mad» from Bright «Mystery of Love» from Call Me by Your Name «Visions of Gideon» from Call Me by Your Name «Captain Underpants Theme Song» from Captain Underpants The First Epic Movie «Ride» from Cars 3 «Run That Race» from Cars 3 «Tell Me How Long» from Chasing Coral «Broken Wings» from City of Ghosts «Remember Me» from Coco «Prayers for This World» from Cries From Syria «There's Something Special» from Despicable Me 3 «It Ain't Fair» from Detroit «A Little Change in the Weather» from Downsizing «Stars in My Eyes (Theme From Drawing Home)» from Drawing Home «All In My Head» from Elizabeth Blue «Dying for Ya» from Elizabeth Blue «Green» from Elizabeth Blue «Can't Hold Out on Love» from Father Figures «Home» from Ferdinand «I Don't Wan na Live Forever» from Fifty Shades Darker «You Shouldn't Look at Me That Way» from Film Stars Don't Die in Liverpool «This Is How You Walk On» from Gifted «Summer Storm» from The Glass Castle «The Pure and the Damned» from Good Time «This Is Me» from The Greatest Showman «The Hero» from The Hero «How Shall a Sparrow Fly» from Hostiles «Just Getting Started» from If You're Not in the Obit, Eat Breakfast «Truth to Power» from An Inconvenient Sequel: Truth to Power «Next Stop, The Stars» from Kepler's Dream «The Devil & The Huntsman» from King Arthur: Legend of the Sword «Have You Ever Wondered» from Lake of Fire «I'll Be Gone» from Lake of Fire «We'll Party All Night» from Lake of Fire «Friends Are Family» from The Lego Batman Movie «Found My Place» from The Lego Ninjago Movie «Stand Up for Something» from Marshall «Rain» from Mary and the Witch's Flower «Myron / Byron» from The Meyerowitz Stories (New and Selected) «Longing for Summer» from Moomins and the Winter Wonderland «Mighty River» from Mudbound «Never Forget» from Murder on the Orient Express «Hold the Light» from Only the Brave «PBNJ» from Patti Cake $ «Tuff Love (Finale)» from Patti Cake $ «Lost Souls» from The Pirates of Somalia «How a Heart Unbreaks» from Pitch Perfect 3 «The Promise» from The Promise «Kaadanayum Kaalchilambe» from Pulimurugan «Maanathe Maarikurumbe» from Pulimurugan «Stubborn Angel» from Same Kind of Different as Me «Dancing Through the Wreckage» from Served Like a Girl «Keep Your Eyes on Me» from The Shack «On the Music Goes» from Slipaway «The Star» from The Star «Jump» from Step «Tickling Giants» from Tickling Giants «Fly Away» from Trafficked «Speak to Me» from Voice From the Stone «Walk on Faith» from Year by the S
in Cell Block 99 «The Crown Sleeps» from The Breadwinner «World Gone Mad» from Bright «Mystery of Love» from Call Me by Your Name «Visions of Gideon» from Call Me by Your Name «Captain Underpants Theme Song» from Captain Underpants The First Epic Movie «Ride» from Cars 3 «Run That Race» from Cars 3 «Tell Me How Long» from Chasing Coral «Broken Wings» from City of Ghosts «Remember Me» from Coco «Prayers for This World» from Cries From Syria «There's Something Special» from Despicable Me 3 «It Ain't Fair» from Detroit «A Little Change
in the Weather» from Downsizing «Stars in My Eyes (Theme From Drawing Home)» from Drawing Home «All In My Head» from Elizabeth Blue «Dying for Ya» from Elizabeth Blue «Green» from Elizabeth Blue «Can't Hold Out on Love» from Father Figures «Home» from Ferdinand «I Don't Wan na Live Forever» from Fifty Shades Darker «You Shouldn't Look at Me That Way» from Film Stars Don't Die in Liverpool «This Is How You Walk On» from Gifted «Summer Storm» from The Glass Castle «The Pure and the Damned» from Good Time «This Is Me» from The Greatest Showman «The Hero» from The Hero «How Shall a Sparrow Fly» from Hostiles «Just Getting Started» from If You're Not in the Obit, Eat Breakfast «Truth to Power» from An Inconvenient Sequel: Truth to Power «Next Stop, The Stars» from Kepler's Dream «The Devil & The Huntsman» from King Arthur: Legend of the Sword «Have You Ever Wondered» from Lake of Fire «I'll Be Gone» from Lake of Fire «We'll Party All Night» from Lake of Fire «Friends Are Family» from The Lego Batman Movie «Found My Place» from The Lego Ninjago Movie «Stand Up for Something» from Marshall «Rain» from Mary and the Witch's Flower «Myron / Byron» from The Meyerowitz Stories (New and Selected) «Longing for Summer» from Moomins and the Winter Wonderland «Mighty River» from Mudbound «Never Forget» from Murder on the Orient Express «Hold the Light» from Only the Brave «PBNJ» from Patti Cake $ «Tuff Love (Finale)» from Patti Cake $ «Lost Souls» from The Pirates of Somalia «How a Heart Unbreaks» from Pitch Perfect 3 «The Promise» from The Promise «Kaadanayum Kaalchilambe» from Pulimurugan «Maanathe Maarikurumbe» from Pulimurugan «Stubborn Angel» from Same Kind of Different as Me «Dancing Through the Wreckage» from Served Like a Girl «Keep Your Eyes on Me» from The Shack «On the Music Goes» from Slipaway «The Star» from The Star «Jump» from Step «Tickling Giants» from Tickling Giants «Fly Away» from Trafficked «Speak to Me» from Voice From the Stone «Walk on Faith» from Year by the S
in the Weather» from Downsizing «Stars
in My Eyes (Theme From Drawing Home)» from Drawing Home «All In My Head» from Elizabeth Blue «Dying for Ya» from Elizabeth Blue «Green» from Elizabeth Blue «Can't Hold Out on Love» from Father Figures «Home» from Ferdinand «I Don't Wan na Live Forever» from Fifty Shades Darker «You Shouldn't Look at Me That Way» from Film Stars Don't Die in Liverpool «This Is How You Walk On» from Gifted «Summer Storm» from The Glass Castle «The Pure and the Damned» from Good Time «This Is Me» from The Greatest Showman «The Hero» from The Hero «How Shall a Sparrow Fly» from Hostiles «Just Getting Started» from If You're Not in the Obit, Eat Breakfast «Truth to Power» from An Inconvenient Sequel: Truth to Power «Next Stop, The Stars» from Kepler's Dream «The Devil & The Huntsman» from King Arthur: Legend of the Sword «Have You Ever Wondered» from Lake of Fire «I'll Be Gone» from Lake of Fire «We'll Party All Night» from Lake of Fire «Friends Are Family» from The Lego Batman Movie «Found My Place» from The Lego Ninjago Movie «Stand Up for Something» from Marshall «Rain» from Mary and the Witch's Flower «Myron / Byron» from The Meyerowitz Stories (New and Selected) «Longing for Summer» from Moomins and the Winter Wonderland «Mighty River» from Mudbound «Never Forget» from Murder on the Orient Express «Hold the Light» from Only the Brave «PBNJ» from Patti Cake $ «Tuff Love (Finale)» from Patti Cake $ «Lost Souls» from The Pirates of Somalia «How a Heart Unbreaks» from Pitch Perfect 3 «The Promise» from The Promise «Kaadanayum Kaalchilambe» from Pulimurugan «Maanathe Maarikurumbe» from Pulimurugan «Stubborn Angel» from Same Kind of Different as Me «Dancing Through the Wreckage» from Served Like a Girl «Keep Your Eyes on Me» from The Shack «On the Music Goes» from Slipaway «The Star» from The Star «Jump» from Step «Tickling Giants» from Tickling Giants «Fly Away» from Trafficked «Speak to Me» from Voice From the Stone «Walk on Faith» from Year by the S
in My Eyes (Theme From Drawing Home)» from Drawing Home «All
In My Head» from Elizabeth Blue «Dying for Ya» from Elizabeth Blue «Green» from Elizabeth Blue «Can't Hold Out on Love» from Father Figures «Home» from Ferdinand «I Don't Wan na Live Forever» from Fifty Shades Darker «You Shouldn't Look at Me That Way» from Film Stars Don't Die in Liverpool «This Is How You Walk On» from Gifted «Summer Storm» from The Glass Castle «The Pure and the Damned» from Good Time «This Is Me» from The Greatest Showman «The Hero» from The Hero «How Shall a Sparrow Fly» from Hostiles «Just Getting Started» from If You're Not in the Obit, Eat Breakfast «Truth to Power» from An Inconvenient Sequel: Truth to Power «Next Stop, The Stars» from Kepler's Dream «The Devil & The Huntsman» from King Arthur: Legend of the Sword «Have You Ever Wondered» from Lake of Fire «I'll Be Gone» from Lake of Fire «We'll Party All Night» from Lake of Fire «Friends Are Family» from The Lego Batman Movie «Found My Place» from The Lego Ninjago Movie «Stand Up for Something» from Marshall «Rain» from Mary and the Witch's Flower «Myron / Byron» from The Meyerowitz Stories (New and Selected) «Longing for Summer» from Moomins and the Winter Wonderland «Mighty River» from Mudbound «Never Forget» from Murder on the Orient Express «Hold the Light» from Only the Brave «PBNJ» from Patti Cake $ «Tuff Love (Finale)» from Patti Cake $ «Lost Souls» from The Pirates of Somalia «How a Heart Unbreaks» from Pitch Perfect 3 «The Promise» from The Promise «Kaadanayum Kaalchilambe» from Pulimurugan «Maanathe Maarikurumbe» from Pulimurugan «Stubborn Angel» from Same Kind of Different as Me «Dancing Through the Wreckage» from Served Like a Girl «Keep Your Eyes on Me» from The Shack «On the Music Goes» from Slipaway «The Star» from The Star «Jump» from Step «Tickling Giants» from Tickling Giants «Fly Away» from Trafficked «Speak to Me» from Voice From the Stone «Walk on Faith» from Year by the S
In My Head» from Elizabeth Blue «Dying for Ya» from Elizabeth Blue «Green» from Elizabeth Blue «Can't Hold Out on Love» from Father Figures «Home» from Ferdinand «I Don't Wan na Live Forever» from Fifty Shades Darker «You Shouldn't Look at Me That Way» from Film Stars Don't Die
in Liverpool «This Is How You Walk On» from Gifted «Summer Storm» from The Glass Castle «The Pure and the Damned» from Good Time «This Is Me» from The Greatest Showman «The Hero» from The Hero «How Shall a Sparrow Fly» from Hostiles «Just Getting Started» from If You're Not in the Obit, Eat Breakfast «Truth to Power» from An Inconvenient Sequel: Truth to Power «Next Stop, The Stars» from Kepler's Dream «The Devil & The Huntsman» from King Arthur: Legend of the Sword «Have You Ever Wondered» from Lake of Fire «I'll Be Gone» from Lake of Fire «We'll Party All Night» from Lake of Fire «Friends Are Family» from The Lego Batman Movie «Found My Place» from The Lego Ninjago Movie «Stand Up for Something» from Marshall «Rain» from Mary and the Witch's Flower «Myron / Byron» from The Meyerowitz Stories (New and Selected) «Longing for Summer» from Moomins and the Winter Wonderland «Mighty River» from Mudbound «Never Forget» from Murder on the Orient Express «Hold the Light» from Only the Brave «PBNJ» from Patti Cake $ «Tuff Love (Finale)» from Patti Cake $ «Lost Souls» from The Pirates of Somalia «How a Heart Unbreaks» from Pitch Perfect 3 «The Promise» from The Promise «Kaadanayum Kaalchilambe» from Pulimurugan «Maanathe Maarikurumbe» from Pulimurugan «Stubborn Angel» from Same Kind of Different as Me «Dancing Through the Wreckage» from Served Like a Girl «Keep Your Eyes on Me» from The Shack «On the Music Goes» from Slipaway «The Star» from The Star «Jump» from Step «Tickling Giants» from Tickling Giants «Fly Away» from Trafficked «Speak to Me» from Voice From the Stone «Walk on Faith» from Year by the S
in Liverpool «This Is How You Walk On» from Gifted «Summer Storm» from The Glass Castle «The Pure and the Damned» from Good Time «This Is Me» from The Greatest Showman «The Hero» from The Hero «How Shall a Sparrow Fly» from Hostiles «Just Getting Started» from If You're Not
in the Obit, Eat Breakfast «Truth to Power» from An Inconvenient Sequel: Truth to Power «Next Stop, The Stars» from Kepler's Dream «The Devil & The Huntsman» from King Arthur: Legend of the Sword «Have You Ever Wondered» from Lake of Fire «I'll Be Gone» from Lake of Fire «We'll Party All Night» from Lake of Fire «Friends Are Family» from The Lego Batman Movie «Found My Place» from The Lego Ninjago Movie «Stand Up for Something» from Marshall «Rain» from Mary and the Witch's Flower «Myron / Byron» from The Meyerowitz Stories (New and Selected) «Longing for Summer» from Moomins and the Winter Wonderland «Mighty River» from Mudbound «Never Forget» from Murder on the Orient Express «Hold the Light» from Only the Brave «PBNJ» from Patti Cake $ «Tuff Love (Finale)» from Patti Cake $ «Lost Souls» from The Pirates of Somalia «How a Heart Unbreaks» from Pitch Perfect 3 «The Promise» from The Promise «Kaadanayum Kaalchilambe» from Pulimurugan «Maanathe Maarikurumbe» from Pulimurugan «Stubborn Angel» from Same Kind of Different as Me «Dancing Through the Wreckage» from Served Like a Girl «Keep Your Eyes on Me» from The Shack «On the Music Goes» from Slipaway «The Star» from The Star «Jump» from Step «Tickling Giants» from Tickling Giants «Fly Away» from Trafficked «Speak to Me» from Voice From the Stone «Walk on Faith» from Year by the S
in the Obit, Eat Breakfast «Truth to Power» from An Inconvenient Sequel: Truth to Power «Next Stop, The Stars» from Kepler's Dream «The Devil & The Huntsman» from King Arthur: Legend of the Sword «Have You Ever Wondered» from Lake of Fire «I'll Be Gone» from Lake of Fire «We'll Party All Night» from Lake of Fire «Friends Are Family» from The Lego Batman Movie «Found My Place» from The Lego Ninjago Movie «Stand Up for Something» from Marshall «Rain» from Mary and the Witch's Flower «Myron / Byron» from The Meyerowitz Stories (New and Selected) «Longing for Summer» from Moomins and the Winter Wonderland «Mighty River» from Mudbound «Never Forget» from Murder on the Orient
Express «Hold the Light» from Only the Brave «PBNJ» from Patti Cake $ «Tuff Love (Finale)» from Patti Cake $ «Lost Souls» from The Pirates of Somalia «How a Heart Unbreaks» from Pitch Perfect 3 «The Promise» from The Promise «Kaadanayum Kaalchilambe» from Pulimurugan «Maanathe Maarikurumbe» from Pulimurugan «Stubborn Angel» from Same Kind of
Different as Me «Dancing Through the Wreckage» from Served Like a Girl «Keep Your Eyes on Me» from The Shack «On the Music Goes» from Slipaway «The Star» from The Star «Jump» from Step «Tickling Giants» from Tickling Giants «Fly Away» from Trafficked «Speak to Me» from Voice From the Stone «Walk on Faith» from Year by the Sea
Using a publicly available gene expression dataset of 79
different cell types, we found that most of the differentially methylated genes are indeed
expressed in T
cells (see File S1).