Strikingly, when miR - 940 was
expressed in bone - resorbing breast cancer
cells, the
cells triggered bone - forming lesions in mice —
behaving as though they were prostate cancer
cells.
Specifically, we have generated clusters of transcripts that
behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES
cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and
Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES
cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.