Sentences with phrase «expressing cells produced»

Most ILCs that produced IL - 22 also produced GM - CSF, but not all GM - CSF expressing cells produced IL - 22 (Fig 6B).

Not exact matches

The scientists discovered that the two sides of the cell differ in the composition of messenger RNA, or mRNA: About 30 percent of the genes expressed in the intestines produced mRNAs that appeared either on one side of the cell or on the other.

A team led by Byeong - Chun Lee of Seoul National University in South Korea created the dogs by cloning fibroblast cells that express a red fluorescent gene produced by sea anemones.

Interestingly, two additional Nature papers released simultaneously with the Regev and Kuchroo team's study revealed that ILC2 cells in the gut also express Nmur1, take on an inflammatory state when exposed to NMU, and live in close proximity to NMU - producing nerve cells.

The work, which appears in the November 27, 2014, edition of Science Express, points to new avenues for producing single - site supported gold catalysts that could produce high - grade hydrogen for cleaner energy use in fuel - cell powered devices, including vehicles.

When a cell in your body expresses a gene, it produces a specific protein.

Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal.

The new study revealed that pancreatic cancer cells not only send signals that make macrophages produce abnormal amounts of dectin - 1 surface receptors, but also that make tumor cells themselves express high levels of galectin - 9.

The bone matrix being produced by cells is stained red in samples of cells that are sorted for not expressing ALPL (left), sorted for expressing ALPL (right), and left as an unsorted control (center).

S. mansoni IPSE binds to Immunoglobulin E (IgE), an antibody produced by the immune system that is expressed on the surface of basophils, a type of immune cell; and mast cells, another immune cell that mediates inflammation; and sequesters chemokines, signaling proteins that alert white cells to infection sites.

In the current study, Dr. Rudnicki and his team discovered that muscle stem cells also express the dystrophin protein, and without this protein, they produce ten-fold fewer muscle precursor cells, which in - turn generate fewer functional muscle fibres.

Gauthier, Miller and co-workers engineered cells to express amino acid biosynthesis enzymes, which enabled cells to grow on their own supply of amino acids produced from supplemented precursors.

The team went on to show that supplementing heavy stable isotope - labeled forms of these precursors led to incorporation of heavy amino acids into proteins produced in enzyme expressing cells.

A complementary DNA for the Aequorea victoria green fluorescent protein (GFP) produces a fluorescent product when expressed in prokaryotic (Escherichia coli) or eukaryotic (Caenorhabditis elegans) cells.

Several research teams had reasoned that if yeast cells could be engineered to express mannosidase, the cells wouldn't produce the mannose - rich sugar complexes that are so immunogenic to humans.

This suggests that the instantaneous peak power delivered to the specimen may be an even more important metric of cell health than the total photon dose and should enable extended 3D observation of endogenous levels of even sparsely expressed proteins produced by genome editing.

And on page 1693, another team reports further evidence of the action of natural selection in people: A gene expressed in microglia, immune cells of the nervous system, produces a protein found only in humans.

These mutations are inserted into batches of yeast or bacterial cells, which express the altered gene and produce millions of random protein variants.

Glioblastoma cells do not naturally produce NY - ESO - 1, so the drug decitabine is given prior to injecting the NY - ESO - 1 targeting T cells in order to cause the tumor cells to express the NY - ESO - 1 target.

The mice they studied are engineered to express human leukocyte antigen, which helps regulate the human immune system, and, in this case, helped the mice produce the powerful T cells again human cancer.

In the proposed project, Dr. Lampi Hermanson will produce NK cells from stem cells, inserting a chimeric antigen receptor (CAR) with the capacity to recognize mesothelin cells, which is expressed in 70 % of ovarian cancer patients.

The mRNAs are delivered to the body and direct cells to produce and express both antigenic proteins on the cell surface, much like a native infection would do but without the ability to cause disease or spread.

In addition, the data showed that the gut's hormone - producing enteroendocrine cells (EECs)-- long divided into subsets based on the idea that each only expressed a single hormone — can actually express multiple hormones at once.

The researchers particularly identified three novel candidate genes; KIRREL3 and SLIT1, with documented roles in immune cell development, and SERPINA9 expressed exclusively at the site (germinal center) where a B - cell starts producing IgA.

Cells produce CN54 gp140 protein expressed into media.

The mRNA directs cells to produce and express the proteins on the cell surface, much like a native infections would do, but without the ability to cause disease.

The vaccines deliver mRNA encoding for hemagglutinin to the body's cells, directing them to produce and express this viral antigenic protein transiently on the cell's surface, much like a native infection would do, but without the ability to cause disease.

Cells produce — or «express» — great quantities of survivin just before they undergo the process of cell division, also called mitosis.

«In cells that don't produce antibodies, like fibroblasts or T - cells, these antibody genes are attached to the inner nuclear membrane and are not recombined or expressed,» said Singh.

Expression of the familial PD - linked A53T or A30P mutant ASs in cell models results in an increased proportion of CTTAS being produced than is the case when expressing the WT protein; consistent with this, a higher proportion of the total soluble AS in human brain tissue with AS neuropathology is CTTAS, and a higher proportion yet of the total AS in insoluble AS deposits.

Each olfactory nerve cell expresses just one of these olfactory genes to produce a receptor that recognizes a related set of odors.

Since we know the Gal4 - UAS system is sensitive to temperature and in fact, expression levels of these transgenes differ at 22 °C and 25 °C, Drosophila GBPs might also suppress ILP secretion from the insulin - producing cells when expressed at high concentrations.

The genes that are switched on, or «expressed,» cause the cell to produce proteins and behave in certain ways.

(A, B) Culturing wild - type brains with conditioned media from GBP1 and GBP2 expressing cells induces low level of ILP2 (A) and ILP5 (B) accumulation in the insulin - producing cells.

(C, D) Culturing wild - type brains with conditioned media from GBP1 and GBP2 expressing cells decreases the densities of ILP2 (C) and ILP5 (D) signals in the insulin - producing cells.

The plated cells were then dissociated and counted using a hemocytometer in order to express results as picograms or nanograms of growth factor produced per day per million cells.

Five beagles were created by cloning fibroblast cells that express a red florescent gene produced by sea anemones.

Although CD144 - or CD31 - producing cells were seen as early as 3 days in vitro (not shown), a homogeneous monolayer of CD144 and CD - 31 expressing cells was seen by 8 to 10 days of exposure to high density culture conditions (Figure 1F — 1H).

Next, to assess the effect of Notch1 activation, 231 cells were produced that stably expressed doxycycline - inducible N1 - ICD (231 - YNICD; ref.

Registry parts include operators, which are segments of DNA to which repressor proteins bind to prevent gene transcription; cell - cell signaling elements, which produce defined outputs in response to specific chemical inputs; and riboregulators, which can be used to suppress the expression of particular genes by preventing translation of proteins they express.

Sclerostin is a protein produced by bone cells which has a negative impact on the formation of bone when expressed at high levels by decreasing bone formation, and IGF - 1 is a hormone associated with the growth of bone.

Re-directed Autologous T cell Therapy for drug resistant or refractory CD20 + B cell lymphoma Overview: In this approach, immune cells (known as T cells) are taken from the peripheral blood, genetically modified in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-...]