Not exact matches
The researchers found that the blond hair commonly seen in Northern Europeans is caused by a
single change in the DNA that regulates the
expression of a gene that encodes a
protein called KITLG, also known as stem cell factor.
Importantly, patients with mutations in a
single copy
of NKX2.1 often have Brain - Lung - Thyroid Syndrome, which is characterized by respiratory distress after birth and accompanied by decreased surfactant
protein expression.
The team
singled out the gene Mecp2, which encodes a
protein that regulates the
expression of genes that help forge connections between nerve cells.
Topics for the scientific sessions are:
Single cell genomics and gene
expression Genetic interactions RNAi and somatic cell genetics
Protein - DNA interactions Cancer The meeting also highlights existing opportunities for academic and industrial researchers to access automated cell - based and biochemical technologies based at the Karolinska High Throughput Center; home to one
of the most sophisticated, state -
of - the - art, ultra-high performance liquid handling and analysis platforms in Europe.
Comparison
of mRNA and
protein expression revealed distinct
expression profiles for many genes and underscores the importance
of multi-omic analysis in
single cells.
July 3, 2013 New mechanism for human gene
expression discovered In a study that could change the way scientists view the process
of protein production in humans, University
of Chicago researchers have found a
single gene that encodes two separate
proteins from the same sequence
of messenger RNA.
microRNAs (miRNA)-- small, hairpin - like structures
of single - stranded RNA molecules that can regulate the
expression of protein - coding genes.
This technology — vectored contraception — utilizes a
single intramuscular injection to bring about transgene - mediated
expression of proteins that inhibit fertility through action on targets such as GnRH, a master reproductive hormone, the egg zona pellucida, which is an essential binding site for sperm, or sperm.
Thus, as anticipated from earlier studies, heterogeneity
of pluripotency gene
expression in
single cells is to a degree reflected at the
protein level.
Consistent with this, WDR26 loss -
of - function
single - nucleotide mutations identified in these subjects lead to nonsense - mediated decay with subsequent reduction
of RNA
expression and
protein levels.