Sentences with phrase «expression of the major genes»

At the same time, there was a similar increase in the expression of the major genes that mediate insulin signaling.

Not exact matches

Because epigenetics is the real driver of your health status, and diet plays a major role in gene expression (aka epigenetics), at least in this post's animal study!

Expression of a microinjected porcine class I major histocompatibility complex gene in transgenic mice

The researchers discovered that both major living lineages of birds (the common neognaths and the rarer paleognaths) differ from the major lineages of non-bird reptiles (crocodiles, turtles, and lizards) and from mammals in having a unique, median gene expression zone of two different facial development genes early in embryonic development.

This system plays a major role in the regulation of gene activity, and enables the selective expression of different functions in differentiated cell types.

Last December, the same research team demonstrated blocking the expression of the gene that encodes apoC - III led to major relief of triglyceridemia in patients suffering a rare and extreme form of hypertriglyceridemia, which in turn opened the door for the identification of unexpected mechanisms that govern blood fat.

«RB loss causes a major reprogramming of gene expression, allowing induction of pathways that promote features that induce characteristics of lethal disease,» said senior author Karen Knudsen, PhD, Director of the Sidney Kimmel Cancer Center (SKCC) at Thomas Jefferson University.

Dodder, a parasitic plant that causes major damage to crops in the U.S. and worldwide every year, can silence the expression of genes in the host plants from which it obtains water and nutrients.

When the team looked at what gene signatures the RORγt - dependent ILCs expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display foreign proteins to the immune system and directly interact with T cells.

The researchers report in Neuron that serotonergic neurons come in at least six major molecular subtypes defined by distinct expression patterns of hundreds of genes.

We predicted a link between gene expression evolution across species and the degree of sexual selection, but this is the first statistical evidence for it and shows how powerful sexual selection can be in leading to major changes in how a gene is expressed.»

A major process of gene expression is transcription, by which RNA is synthesized according to a DNA template.

«Regarding the other histones, which are major proteins in the regulation of gene expression, we know which enzymes modify them, their functions, and how they are regulated... But for some reason, the functions of histone 1 have not been addressed,» he adds.

The Human Protein Atlas has reached a major milestone by releasing protein data for more than 80 % of the human protein - coding genes and RNA expression data for more than 90 % of the genes.

«I think we've filled in a major gap in the understanding of how gene expression is linked to the local organization of chromosomes,» says Hnisz.

Bach1 is a member of the BTB and CNC transcriptional regulator family that, like Nrf2, binds to ARE sequences as heterodimeric complexes with small Maf proteins [18] A major physiological role for Bach1 is in iron homeostasis through regulation of the expression of heme oxygenase - 1 (HMOX1), ferroportin (FPN1) and Ferritin (FTH) genes [23], [24], [33], [41].

Single loci with major effects in fire ants: the effects of the complementary sex - determining locus and the green beard supergene on gene expression

The aim of his research was to use microarray gene expression data in order to characterize ageing in different human tissues and identify the age at which major changes in genetic expression profiles occur.

Sexual selection has been proposed to be the major force driving this fast divergence of male reproductive traits, gene sequences, and their expression patterns [9], [10], [12].

In a major advance for the nascent field of RNA nanotechnology, nanoparticles composed solely of chemically modified RNA were assembled, found to survive circulation in the bloodstream, be non-toxic and non-immunogenic, internalize into cancer cells specifically, and silence expression of cancer - promoting genes.

High - throughput ChIP - Seq: One of the major questions for researchers interested in understanding chromatin dynamics is to investigate how protein - DNA interactions alter Epigenetic profiles and subsequent gene expression.

Transposons are known to affect the regulation of gene expression and play major roles in shaping genome structure.

Therefore, BGEM provides the most comprehensive gene expression analysis of any of the major databases.

Because the hypothalamus is a major control center of the endocrine system, appetite and energy balance, Kahn and his team wanted to know how diabetes affects hypothalamic gene expression.

Because epigenetics is the real driver of your health status, and diet plays a major role in gene expression (aka epigenetics), at least in this post's animal study!

Typically, a major transcription factor involved in the expression of detoxification genes known as Nrf2 remains in a dormant state in the body.

They also serve as the major energy source for colonocytes (epithelial cells of the colon) and are thought to regulate human gene expression in order to reduce the risk of gastrointestinal disorders, some forms of cancer, and cardiovascular disease.