Sentences with phrase «expression of the members of the family»

Carlos worked with postdoc John Abramyan on the CBM18 gene family in Bdto confirm gene expression of the members of the family by RT - PCR before we choose a subset to work on further.

Not exact matches

Love to family members and spouse can be an expression of love to God.

(6) To see the positive but abortive growth strivings in much of the frustrating behavior of family members and to learn how to encourage the expression of these strivings in more self - actualizing ways.

This metaphor emphasizes that the autonomy and security of each community's religious experience and expression must be guarded by all members of the extended family, and that the interaction within the common spaces of the house must be governed by mutually agreed codes of conduct allowing for free exchange of ideas and not leading to the theological «annexing» of one unit by another.

Family members express their love and support in many ways — some expressions of love are supportive of breastfeeding and some less so.

This adorable feature makes a little baby's pout and other facial expressions even funnier and endearing which us, as their parents, family members and just adults, in general, can't get enough of.

In SR, by contrast, the literature was a trigger to recall and expression of diverse life experiences — of work, childhood, family members, relationships — related to the entire life - span, not merely the time - period affected by pain, or the time - period pre-pain as contrasted with life in the present.

Using methods for analyzing gene expression in mice, they identified several members of the «BMP» family of proteins from among more than 20,000 possible candidates.

Normally, FOXP2 coordinates the expression of other genes, but in affected members of the KE family, it was broken.

The vector is a self - inactivating lentivirus — a member of a family of viruses that can insert genes into mammalian cells and drive expression of those genes — that has been engineered to avoid triggering the development of leukemia, a complication seen in previous gene therapy trials for immunodeficiency syndromes, including WAS.

Pattern of Expression of p53, Its Family Members, and Regulators during Early Ocular Development and in the Post-Mitotic Retina.

Hsiou - Chi Liou and colleagues find that c - Rel, a lymphoid - specific member of the NF - kappaB / Rel family of transcriptional factors, is essential for B lymphocyte survival and cell cycle progression, [i] and that it is important for inducible cytokine and cytokine receptor expression and a key regulator of early activation and proliferation in T cells.

«Now, for the first time, we've identified NF - kB1 is the «odd one out» in the family because abnormally low expression — or «loss» — of this family member actually causes the development of spontaneous stomach cancers.

«Now, for the first time, we've identified NF - kB1 is the «odd one out» in the family because abnormally low expression - or «loss» - of this family member actually causes the development of spontaneous stomach cancers.

Ongoing T2D research activities at CRGGH include 1) whole - exome sequencing of African families with at least four affected members (data generation is complete and analysis is ongoing), 2) GWAS of 1,200 cases and 1,200 controls from West Africa using the new and more efficient African - centric Affymetrix Axiom genome - wide array with more than 2 million markers, and 3) whole genome expression analysis on skeletal muscle obtained from biopsy from 45 subjects (expression QTL (eQTL) studies on the dataset are complete).

The researchers thus went on to study the expression of Wnt genes during regeneration, and found that different members of the gene family were active at different locations across the planarian's head - to - tail axis.

Bach1 is a member of the BTB and CNC transcriptional regulator family that, like Nrf2, binds to ARE sequences as heterodimeric complexes with small Maf proteins [18] A major physiological role for Bach1 is in iron homeostasis through regulation of the expression of heme oxygenase - 1 (HMOX1), ferroportin (FPN1) and Ferritin (FTH) genes [23], [24], [33], [41].

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

However, when the mice were reconstituted with T cells from aged donors, the expression of the V186.2 gene by young B cells was diminished and the response was dominated by the C1H4 gene, another member of the V186.2 / V3 family.

This investigation showed the expression patterns of p53 protein family members in the reluctantly dividing cells of the human corneal endothelium.

An example of the expression profiles for the 19 members of the Wnt protein family of morphogens in ES cells and during the first 10 days of differentiation, obtained using the FunGenES search engine, is shown in Figure 6.

For those who can not or choose not to give birth, there are other ways to experience the expression of motherhood during this life stage: nurturing others, caring for animals or family members» children, volunteering, and being creative.

The recent recognition that de novo lipogenesis might have relevance for lipid homeostasis in skeletal muscle stems from the realization that Sterol regulatory element binding protein - 1c (SREBP - 1c), a member of the family of transcription factors that regulate the expression of genes involved in lipid storage in liver and adipose tissue, is also present in skeletal muscle at a level close to that observed in the liver, 41,42... [M] ost fascinating are the very recent demonstrations that glucose alone (in the absence of insulin) can stimulate de novo lipogenesis in skeletal muscle cells....

During my first year, when I would tell non-educator friends and family members that the reason I had left school after sundown on the previous night was to finish the planning of lessons for the following day, they would often look at me with a puzzled expression.

His pendulous ears, soft gentle expression, sturdy build and friendly wagging tail proclaim him unmistakably a member of the ancient family of Spaniels.

Shots framing the faces of the family members — whose expressions range from noble to bored, defiant to diffident — are interspersed with close - ups of the sons» hands running over the father's uniform and badge.

73 Moreover, as regards those resources, the expression «recourse to the social assistance system» in Article 7 (1)(c) of Directive 2003/86 does not allow a Member State to refuse family reunification to a sponsor who proves that he has stable and regular resources which are sufficient to maintain himself and the members of his family, but who, given the level of his resources, will nevertheless be entitled to claim special assistance in order to meet exceptional, individually determined, essential living costs or income support measures (see Chakroun, paragraph 52).

You may want to opt for an expression lifestyle plan if you know that your members of the family senior parents members won't rely on you for their economical needs permanently.

Or if a family member expresses love with «gifts» to a partner who feels loved through «quality time» that expression of love won't be understood, felt, or appreciated.

Aggression between approximately six months and three years after birth can be characterized by the use of physical force and expressions of anger directed at family members and peers (Hay, Perra et al., 2010).

Infantile aggression was assessed at 18 months of age using the Cardiff Infant Contentiousness Scale (CICS)(Hay, Perra et al., 2010), which is a measure of the use of physical force and expressions of anger toward family members and peers during infancy comprising 4 items.

A couple members suggested that the children could create gifts for their birth parents as an expression of care and to communicate that exchanging gifts is acceptable in the family dynamic, without creating pressure that could come of outright asking the birth parent to provide a gift.

From these ratings, researchers created two positive engagement variables: (a) one that reflected the overall expression of family positive engagement, and (b) the (adolescent) individual's own unique level of positive engagement with other family members.

There was a tendency for lower expression of both positive and negative emotional reactions towards family members in the Japanese sample (Nomura et al., 2005, p. 566).

Other data showed that there is a significant positive correlation between a high level of family intimacy as well as emotional expression and a high level of self - esteem and self achievement of adolescents (Li et al., 2006); the extent of closeness of family members and the parental expectations might affect the self - esteem and self - concept of the college freshmen (Wu and Ye, 2009).

Each author describes his or her own creative avenue of expression such as puppetry, psychodrama, and sandplay, which facilitate the family's communication, helping members to find new ways to hear each other.

Using new ways of ways expressions may help family members, couples, or individuals, see things from a whole new vantage point.

All family members participating in the therapy are coached in the identification and expression of attachment - related emotions linked to conflict within the family, acceptance and compassion toward the emotions of others, and healthy, positive expression of personal needs and desires.

This conference will explore how emotional process in the family can interact with the expression of certain genes in members of the family that affect our behaviour and our health.

The 27 items are divided among three subscales which assess the support and sense of togetherness between family members (e.g., «We put a lot of energy into what we do at home»); the extent to which family members express their thoughts and feelings (e.g., «Family members often feel like keeping their feelings to themselves») and; the expression of negative emotions towards members of the family unit (e.g., «Family members sometimes get so angry they throw things&rafamily members (e.g., «We put a lot of energy into what we do at home»); the extent to which family members express their thoughts and feelings (e.g., «Family members often feel like keeping their feelings to themselves») and; the expression of negative emotions towards members of the family unit (e.g., «Family members sometimes get so angry they throw things&rafamily members express their thoughts and feelings (e.g., «Family members often feel like keeping their feelings to themselves») and; the expression of negative emotions towards members of the family unit (e.g., «Family members sometimes get so angry they throw things&raFamily members often feel like keeping their feelings to themselves») and; the expression of negative emotions towards members of the family unit (e.g., «Family members sometimes get so angry they throw things&rafamily unit (e.g., «Family members sometimes get so angry they throw things&raFamily members sometimes get so angry they throw things»).

Christian family counseling can help both Christian families, and families with a blend of beliefs learn to better communicate their needs for religious expression, and develop a better understanding and respect for the faith of other family members.