Sentences with phrase «expression studies»
"Expression studies" refers to research or investigations that focus on examining how genes are turned on or off and how this affects the production of proteins or other molecules in a living organism. Full definition
The study suggests that methods based on variance may help get the most from existing and future global gene expression studies.
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We even did gene - expression studies in flies showing that genes in their brains change their level of activity in waking and in sleep.
Based on gene expression studies of fat tissue conducted at the USDA HNRCA, the Tufts University researchers initiated studies of the role of FAT10 in adipose tissue and metabolism.
Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in gene expression studies on lab - grown human breast cancer cells and found that they could mimic estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.
In addition, we support gene expression studies using Quant - seq (3» RNA - seq) and low input sequencing for most applications.
A total of 24 mice were included in the microarray expression study, four from each of the following groups: C57BL / 6J males, C57BL / 6J females, high fat — fed C57BL / 6J males, B6.Cg Ay / + females, B6.V Lepob / ob males, and B6.V Lepob / ob females.
Global gene expression studies found that the LPA - treated mice shared many similar molecular markers as those found in humans with schizophrenia.
Gene expression studies led researchers to find RNA fragments in the bees from viruses that are transmitted by Varroa mites, a long - time foe of honeybees that beekeepers were treating with a variety of pesticides.
Rachael Jack, a psychologist at the University of Glasgow in the United Kingdom, says that there is a fundamental flaw in the facial expression studies carried out since Darwin's time: Researchers have been using Darwin's six basic expressions as their starting point, and yet they were first identified by Western European scientists studying Western European subjects.
To begin to explore the cellular mechanisms that might be responsible for this response, histological analysis revealed less severe disruption of spermatogenesis and gene expression studies suggested that an interplay of ATP - binding cassette (ABC) efflux transporters and solute carrier (SLC) influx transporters in the testicular cells might be involved.
To study the effects of LRO - related gene mutations, Dr. Huizing is performing fluorescent protein expression studies using patients» cells in order to examine defective intracellular trafficking.
Additional platforms for targeted gene expression studies include the nanoString platform supporting all custom or commercially available applications.
Our findings are consistent with results of gene expression studies from non-vascular tissues in differing MPS subtypes.
Genes putatively related to calcification (e.g. calcium and inorganic carbon transport, H + transport and carbonic anhydrases) have been identified via gene expression studies comparing calcifying and non-calcifying E. huxleyi cells [25 — 29], or in short - term experiments where calcification was regulated by limitation of ions needed for calcification (i.e. Ca2 +, HCO3 − / CO32 − [26,30,31]-RRB-.
«Single - nucleus RNA sequencing, droplet by droplet: DroNc - Seq, technology that merges single - nucleus RNA sequencing with microfluidics, brings new scale to gene expression studies in complex tissues.»
Fishing for a cause, Harvard nephrologist Ananth Karumanchi and his colleagues carried out a gene - expression study on placenta samples, collected immediately after delivery, from 17 healthy women and 21 others with preeclampsia.
The team is now working on other conditional knockout and gene expression studies of Esrp1 and Esrp2's roles in the face, lungs, gut, kidney, and other organs.
In gene expression studies, investigators find those genes that are most commonly expressed in either healthy or diseased tissue.
The Netherlands Twin Register has followed twin pairs for over 25 years and in collaboration with the longitudinal Netherlands Study of Depression and Anxiety established a resource for genetic and expression studies.
Pettersson began to suspect a mind - microbe link 5 years ago when he and genomicist Shugui Wang of the Genome Institute of Singapore found through gene - expression studies that gut microbes regulated the activity of a gene important to the production of serotonin, a key brain chemical.
«Atlas of developing human brain launched by researchers: Gene expression study may provide insights into autism, other neurodevelopmental disorders.»
Asked to name the most important use of the samples so far, Beach thinks for a moment and then describes an ambitious gene - expression study, «the first thorough study of gene expression of individually selected nerve cells in several regions of the Alzheimer's brain.»
The list suggests some obvious candidates for gene - expression studies.
One reason is that researchers recently realized that tumor biopsies preserved in paraffin, the most common method, can be used for sequencing and gene expression studies.
DroNc - Seq — a technology that merges single - nucleus RNA sequencing with microfluidics — brings new scale to gene expression studies in complex tissues.
Bioinformatics has now firmly established itself as a discipline in molecular medicine, and encompasses a wide range of subject areas from structural biology, genomics to gene expression studies and personalised medicine.
Hematopoietic stem cells from various sources (bone marrow, cord blood and peripheral blood) are isolated and characterized by phenotyping and gene expression studies.
Here we suggest a novel yet conceptually simple approach for deriving «Functional Association (s) by Response Overlap» (FARO) between microarray gene expression studies.
Molecular Characterization of Mn - superoxide Dismutase and Gene Expression Studies in Dietary Restricted Brachionus plicatilis Rotifers
In 2017, it will be joined by Anipath, a platform devoted to the histological analysis of small animal models including phenotyping, diagnosis of morbidity cause, in situ gene expression studies.
For custom gene expression projects the Genomics Core has a platform that uses sets of human and mouse custom arrays whose probe content is aimed at gene expression studies in the areas of cancer, immunology and other complex diseases.
Multiple real - time PCR platforms are available for gene expression studies, including Agilent Mx3005p and Mx3000p instruments, a Roche LightCycler 480 II with interchangeable 96 - and 384 - well modules, and a Roche LightCycler 1536 with an associated Innovadyne Screenmaker 96 +8 liquid handling workstation.
We use large - scale gene expression studies and phenotypic analyses in defined sets of mouse strains (so - called genetic reference populations) as well as sophisticated biomathematical tools to learn about how high - dimensional gene - gene interactions respond to the activity - dependent stimulus and affect the stem cells and developing new neurons.
The presentation describes integration of family studies, genomic analysis and expression studies for gene discovery and characterization.