Sentences with phrase «expression studies found»

Global gene expression studies found that the LPA - treated mice shared many similar molecular markers as those found in humans with schizophrenia.

Not exact matches

Our study in an animal model found that influenza infection leads to an increase in the expression of muscle - degrading genes and a decrease in expression of muscle - building genes in skeletal muscles in the legs.

Studies have found that introverts are actually pretty good at reading facial expressions.

Nor is it to deny that Whitehead could find his way to new ideas while developing or giving expression to old Ones.5 But there is no reason to expect the dramatic shifts in metaphysical outlook or doctrine so often posited by Ford's genetic studies.6

One study found that learning hand expression during pregnancy increased mothers» confidence and readiness for breastfeeding.4 Another study found that it increased not only breastfeeding confidence, but also how long they breastfed.5 Experimenting slowly with hand expression to figure out what it takes to get drops of milk can be empowering, especially during pregnancy before there's any pressure to express milk for the baby.

In fact, a past study called the «still face» experiment found that children notice their parents» blank expressions.

A new study in Biological Psychiatry found that heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression.

The idea to specifically study this group of patients was based on groundbreaking research Garon published in the New England Journal of Medicine last year, which found that among patients who received pembrolizumab, those with PD - L1 expression on at least 50 percent of their cancer cells showed the longest survival and disease control.

Whether you are studying the expression of thousands of genes simultaneously using DNA microarrays, or the interaction of multiple molecules to understand intercellular signalling, the skills that will help you understand your findings are statistics, computational techniques, and modelling — so all you really need is a mathematician.

Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in gene expression studies on lab - grown human breast cancer cells and found that they could mimic estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.

A new study finds that your use of facial expressions, such as smiles, is related to the migratory history of where you're from.

By examining gene expression patterns, the new study found that parrot brains are structured differently than the brains of songbirds and hummingbirds, which also exhibit vocal learning.

Underscoring the relevance to humans, the researchers studied nasal and bronchial cells from people who suffer from asthma or chronic rhinosinusitis (nasal congestion / sniffles) due to dust - mite sensitivity, and found that on average these cells had a markedly lower expression of the dectin - 1 gene.

A joint study by researchers at the University of California, San Diego and the University of Toronto has found that a computer system spots real or faked expressions of pain more accurately than people can.

Visel and his colleagues studied gene expression in a developing mouse embryo, and found 120 enhancers active in cells of the face.

Judith Zelikoff of NYU Langone Medical Center studied pre - and post-natal exposure to mice of commercially available e-cigarette vapors and aerosols with and without nicotine, finding changes to frontal cortex gene expression associated with mental health and activity issues, some of which are associated with schizophrenia, she said.

«As a result of the previous study, we reported that SUMO is probably important for controlling expression of active genes because we found it on every gene we looked at, but only when they were turned on,» notes Rosonina.

In prior studies, Desgrosellier and team found that αvβ3 expression acts as a switch during early pregnancy to activate normal mammary stem cells as the body remodels to prepare for a baby.

In previous studies, Chen - Yu Zhang's group has reported a striking finding that plant miRNAs are ingested from plant diets and pass through the gastrointestinal tract, enter into the blood, accumulate in tissues and regulate endogenous gene expression in animals.

«We found that expression of glucose transporters is completely shut down by bacteria, leaving insufficient fuel for the immune cells to fight off the infection,» said the study's first author, Subramanian Krishnan, PhD, of the Division of Infectious Diseases at CHLA.

The research draws from previous findings by molecular biology and genetics professor and study co-author Mariana Wolfner on how Drosophila females» gene expression, behavior and physiology are changed by mating.

That's the conclusion of a groundbreaking study into human expressions of emotion, which found that people are able to correctly identify other people's feelings up to 75 percent of the time — based solely on subtle shifts in blood flow color around the nose, eyebrows, cheeks or chin.

In the new study, the team genetically inactivated HIV - 1 in transgenic mice, reducing the RNA expression of viral genes by roughly 60 to 95 percent, confirming their earlier findings.

But the researchers found no significant changes in the expression of genes known to be involved in calcification from prior studies comparing strains with dramatically different calcification levels.

«Not only did we find that LIGHT expression promoted tumor regression, upon further study we also identified the specific type of T - cell — CD8 — that was responsible for shrinking the tumor,» Maker said.

The researchers in the Greenberg lab found that across all analyzed datasets, and in studies of different mouse brain regions, in the absence of MECP2 the expression of long genes is increased.

In a 2015 study of 46 people, Bearden found that people with 22q11.2 deletion syndrome who have autism show different patterns of gene expression than do those with the syndrome who have schizophrenia3.

«These findings raise the possibility that by determining the gene expression profile of a patient's tumor, physicians may be able to identify aggressive disease at the outset of diagnosis and start treatment earlier,» said Sungyong You, PhD, an instructor in the Cedars - Sinai Department of Surgery and the first author of the study.

The team used gene expression profiling and found that canine B - cell lymphoma expression profiles were similar in many ways to human B - cell lymphoma, thus paving the way for future studies, including therapeutic clinical trials in dogs and humans.

Another study, which Sasson and Pinkham published last year, found that when people with schizophrenia do take note of faces, they are more prone than people with autism or typical people to jump to the wrong conclusions if the expressions are hard to decipher.

Anguera's studies found that, in some cases, stem cells lose both Xist expression and the modifications that normally reside on the inactive X.

«It has taken us years to assemble the clinical outcome database and tissue samples, generate the immunohistochemical biomarkers, gene expression profiles and analyse the data for this study — and we were delighted to find a definite link between alpha beta crystallin and breast cancer progression, which we hope will ultimately improve clinical outcomes.

The teenagers with conduct disorder struggled to recognize anger, fear, happiness, sadness and surprise in facial expressions, in line with findings from previous studies.

The researchers went into this study expecting to find that the microbes signaled the host to open up areas of chromatin to activate gene expression in the gut.

He has been studying differences in gene expression in infected and uninfected plants and finds that the fungus seems to increase the activity of genes involved in seed production.

Recent studies have found elevated levels of this protein in post-mortem brain samples of patients with MS.. In this latest work, investigators compared the frequencies of «more active» and «less active» variants of the DNA sequences that control expression of the galanin gene between healthy controls and MS patients.

The study also analyzed tumors for expression of PD - L1, a cancer immunotherapy target, and found that sarcomatoid histology, a subtype of the mesothelioma, might be a good candidate for anti-PD-L1 therapy.

For the first time, it is now found by a study that various mechanisms of transcribing DNA into RNA exist during gene expression in the different development phases of zebrafish.

«These findings suggest that focusing on genes with conserved expression levels among primates may be helpful in identifying promising candidates for disease - association studies,» the researchers write.

Mao's study examined mitochondria - associated gene expression in the mouse eye tissue and found significant changes in several genes involved in oxidative stress response.

Humans have an ortholog of the murine Nrk gene, and considering that the gene expression pattern in breast tumor in Nrk mutant mice was similar to that in human luminal B breast cancer, the findings of this study may lead to further understanding of the mechanisms of human breast cancer suppression and to advances in its diagnosis and therapy.

Oncologists welcome gene expression profiling tests as an added tool in deciding whether women with early - stage breast cancer should have chemotherapy, a new study has found.

The finding wasn't surprising, Fallin explains — numerous studies have identified abnormal gene expression of immune genes in autism samples and environmental experiences such as prenatal infection or prenatal exposure to pollutants that can ramp up immune responses are risk factors for ASD.

Among the study findings, IR mutations alter expression of many genes both in fibroblasts and iPSCs compared to normal cells, «but the impact is very much dependent on the cell type,» says Kahn.

Using studies in both mice and humans, they found that exposure to farm dust increases expression of a protective protein that suppresses the inflammatory immune system by modifying the communication between the lining of the lungs and the immune system.

All microarray data supporting the findings of this study have been deposited in the National Center for Biotechnology Information Gene Expression Omnibus (GEO) and are accessible through the GEO Series accession number GSE86885.

The new study found significant hypermethylation in the most aggressive meningiomas, and showed that these DNA modifications specifically silenced genes that usually inhibit FOXM1 expression and Wnt signaling.

These findings for scoring expression were agreed with Gillet et al., 1996 [24], who stated in their study that, moderate / strong staining of Cyclin D1 had a longer relapse - free survival than patients whose tumors stained weakly or negatively for Cyclin D1 with a great significant difference (P = 0.007).

(14,15)-RRB- have found age - related satellite cell attrition consistent with the senescence of a subset thereof; moreover, one such study (15) reported that decreases in the number and quality of satellite cells with aging are reliably associated with elevated expression of p16Ink4a (contrary to (14)-RRB-, and with secretory and proteomic abnormalities consistent with a rising burden of senescent cells.

July 3, 2013 New mechanism for human gene expression discovered In a study that could change the way scientists view the process of protein production in humans, University of Chicago researchers have found a single gene that encodes two separate proteins from the same sequence of messenger RNA.