Sentences with phrase «expression studies led»

Not exact matches

Our study in an animal model found that influenza infection leads to an increase in the expression of muscle - degrading genes and a decrease in expression of muscle - building genes in skeletal muscles in the legs.

The study could then lead participants to explore feminine expressions for humankind.

An additional study, currently available at bioRxiv, led by the researchers from the CRG and Cold Spring Harbour Laboratory, highlights the fact that a substantial part of human and mice genes have maintained an essentially constant expression throughout evolution, in tissues and various organs.

«The computer system managed to detect distinctive dynamic features of facial expressions that people missed,» said Marian Bartlett, research professor at UC San Diego's Institute for Neural Computation and lead author of the study.

In this study, a team led by Panos N. Papapanou, DDS, PhD, professor and chair of oral, diagnostic and rehabilitation sciences at the College of Dental Medicine at CUMC, «reverse - engineered» the gene expression data to build a map of the genetic interactions that lead to periodontitis and identify individual genes that appear to have the most influence on the disease.

Using an innovative crystallization technique for studying three - dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the «magic spot» — a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

While the muscles for making basic facial expressions are standard issue, some people have extra equipment, according to a study led by psychologist Bridget Waller of the Centre for the Study of Emotion at the University of Portsmouth in Engstudy led by psychologist Bridget Waller of the Centre for the Study of Emotion at the University of Portsmouth in EngStudy of Emotion at the University of Portsmouth in England.

While previous investigations into the protein's effects have used either mice in which gene expression was knocked out or transgenic animals that expressed human gene variants throughout their lifetimes, the MGH - MIND - led study used a different approach to investigate the effects of introducing the variant forms of the protein into brains in which plaque formation had already begun.

Lead author Johan den Boon, associate scientist with the Morgridge Institute for Research at the University of Wisconsin - Madison, says the research team used gene expression profiling on 128 specimens from the Study to Understand Cervical Cancer Early Endpoints and Determinants, or SUCCEED.

«TIA - 1 is known for its ability to regulate gene expression during cellular stress,» says Hewett, who studies the processes that suppress the severe electrical storms in the brain, leading to seizures.

Emotion usually leads to an expression, but studies have shown that the process can also work in reverse: If you force your face to look sad or angry, the rest of your body will react as well, and you may involuntarily begin to feel those emotions.

The study, led by Michael Greenberg, Ph.D., Chairman of the Department of Neurobiology at Harvard University, shows that MECP2 dampens the expression of long genes.

In the new study, a team led by Vanessa Dumeaux during her time at McGill University examined links between gene expression in breast cancer tumors and in the bloodstream.

Humans have an ortholog of the murine Nrk gene, and considering that the gene expression pattern in breast tumor in Nrk mutant mice was similar to that in human luminal B breast cancer, the findings of this study may lead to further understanding of the mechanisms of human breast cancer suppression and to advances in its diagnosis and therapy.

Expanding from their previous studies with mice, the researchers first established that under specific conditions, culturing human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers for the cerebellar plate neuroepithelium — the part of the developing nervous system specific for the cerebellum — within five.

Previous studies have shown a physiologic role for vitamin D in liver function, but «it was our discovery of high levels of vitamin D receptor (VDR) in the stellate cell that led us to consider it as a possible off switch for liver fibrosis,» says lead author Ning Ding, a research associate in the Gene Expression Laboratory.

«We observed small but significant changes in the gene expressions between normal and diabetic corneas,» said Mehrnoosh Saghizadeh Ghiam, PhD, assistant professor of biomedical sciences and neurosurgery, a researcher in the Regenerative Medicine Institute Eye Program and the lead author of the study published in the journal PLOS ONE.

Increased expression of a gene linked to autism spectrum disorders (ASDs) leads to a remodeling of dendrites during brain development, according to a new study conducted in cultured neurons and an ASD mouse model published in JNeurosci.

Nishikura studies the process of RNA editing and has made pioneering strides in the understanding of how our cells utilize RNA to control gene expression and protein synthesis and how the malfunction of this process can lead to disease.

In the first study to run a genome - wide analysis of Short Tandem Repeats (STRs) in gene expression, a large team of computational geneticists led...

In 2005, a team of researchers at the Spanish National Cancer Research Centre led a study that analyzed DNA methylation patterns to see how they affected gene expression in identical twins ranging in age from 3 to 74.

Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia (ALL), according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.

Clostridium botulinum produces a transcription factor that can aggregate and self - propagate a prion - like form, leading to genome - wide changes in gene expression in E. coli, according to a study.

To investigate the underlying mechanisms, we undertook (1) bioinformatic, functional genomic annotation and human osteoblast expression studies; (2) gene - function prediction; (3) skeletal phenotyping of 120 knockout mice with deletions of genes adjacent to lead independent SNPs; and (4) analysis of gene expression in mouse osteoblasts, osteocytes and osteoclasts.

The authors of the in vitro study state, «Based on our results, we concluded that gliadin activates zonulin signaling irrespective of the genetic expression of autoimmunity, leading to increased intestinal permeability to macromolecules» (Drago et al., 2006, p. 408).

In fact, a recent study by Arakawa and colleagues of thyroid patients with Hashimoto's and Graves» found that polymorphisms — that is, gene variations that may lead to the abnormal expressions — were as common in autoimmune thyroid disease as they were in the normal population.

Top industry professionals lead a focused and comprehensive study of key typeface design principles: technique, aesthetics, expression, history, and theory.

In high school I'd been led to believe that the study of traditional painting techniques was a common jumping off point to more personal types of expression (think Picasso and Duchamp), but for some reason, probably my punk hair and clothes, the in - crowd at school considered my type of tight, facile realism to be threatening.

«I believe that the expression «case study» understates the point of your first comment of this subthread: -LSB-...]» -LSB-...] «Instead of a case study, I am tempted to see character assassination, scapegoating, or a process by which led to the practice of pittura infamante: -LSB-...]»

Other studies (e.g., Anderson et al., 2008) have shown that high levels of stress (such as that induced by exposure to ACEs) lead to dysregulation of the limbic system, resulting in a rewiring of the brain which causes children to be more anxious and hyper - responsive to negative social cues, such as angry facial expressions from others.

In Study 2 (inner city), compared to the established prevention program I Can Problem Solve, EBP led to greater increases in emotion knowledge, emotion regulation, positive emotion expression, and social competence.