Sentences with phrase «extension of the lifespan»

«How much of our findings with regards to lifespan extension will spill over to mammals is anyone's guess, for example the extension of lifespan might not be as dramatic,» says Petrascheck.

«We have found that the restriction and redirection of NMD has a major influence on the extension of lifespan under conditions of DR,» Rogers explained.

Superoxide dismutases (SODs) promote a conversion of harmful reactive oxygen species (ROS) to relatively moderate forms, resulting in the extension of lifespan in the nematode Caenorhabditis elegans

Observed effects include increased insulin sensitivity, reversal of mitochondrial dysfunction, reduced stem cell senescence, and extension of lifespan (Bai et al., 2011; Gomes et al., 2013; Yoshino et al., 2011; Zhang et al., 2016).

Not exact matches

«He enables his clients to make radical breakthroughs in their immediate day - to - day health, cognitive functioning and physical performance — all of which increase their prospects for Optimal Health and significant Lifespan Extension.»

«In this study, we used the small roundworm C. elegans as a model to show that autophagy in the intestine is critical for lifespan extension,» said Malene Hansen, Ph.D., associate professor in SBP's Development, Aging, and Regeneration Program and senior author of the study.

Calorie restriction does not elicit a robust extension of replicative lifespan in Saccharomyces cerevisiae.

«However, lifespan extension accomplished through a deceleration of the aging process will lead to lower healthcare expenditures, higher productivity, and greater well - being.»

Scientists at the Buck Institute combined mutations in two pathways well - known for lifespan extension and report a synergistic five-fold extension of longevity in the nematode C. elegans.

Like this, the researchers from Jena, Berlin and Duisburg - Essen were able to conclude that lifespan extension in rodents can be attributed to changes in their defense against free radicals, iron homeostasis as well as cellular respiration and translation as central parts of the growth program.

These targets were chosen as they aren't closely related but, despite this, a lifespan extension of around 10 percent on average was seen across the experiments when Pol III activity was only modestly reduced in adult organisms.

In addition, it has been reported that median lifespan extension in CR heterozygote SIRT1 (±) mice was identical (51 %) to that observed in wild - type mice, but SIRT1 (±) mice displayed a higher frequency of certain pathologies 13 highlighting its important role in age - related diseases.

The mouse lifespan study is the important news here, as it demonstrates meaningful extension of median life span through removal of senescent cells, the first such study carried out in normal mice for this SENS - style rejuvenation technology.

Well, this study was able to delete certain lifespan - shortening calorie and inflammatory genes (creating a state of caloric restriction) with at best, a 60 % lifespan extension (living to 60 - 90 days, very good!

Genetic variations and environmental conditions that result in lifespan extension are also associated with delaying the onset of age - related diseases including diabetes, cancer, and neurodegeneration.

The biological mechanisms of lifespan extension through calorie restriction are not fully understood, but researchers say it may involve alterations in energy metabolism (as mentioned above), reduced oxidative damage, improvements in insulin sensitivity, reduction of glycation, modulation of protein metabolism, downregulation of pro-inflammatory genes and functional changes in both neuroendocrine and autonomic nervous systems.

The lesson consists of differentiated learning outcomes based on Bloom's taxonomy, extension tasks, timings, plenaries, homework tasks, case studies and opportunities for revision for unit 1 (human lifespan) as well as unit 2 exam questions and opportunities to develop exam technique.

The impressive graphics helped Donkey Kong Country become a massive success, which in turn lead to an extension of the SNES» lifespan and, ultimately, the console's «victory» over the Sega Genesis.

Marion Solomon, Ph.D., is Director of Training, Lifespan Learning Institute; Lecturer at the David Geffen School of Medicine, Department of Psychiatry at UCLA; and Senior Extension faculty at the Department of Humanities, Sciences and Social Sciences at UCLA.