Sentences with phrase «extra-long huntingtin»

First off, all of this new research on the role of the helper complex and mTOR in making extra-long huntingtin protein was done in cells or mice.

During translation, however, the RNA instructions for extra-long huntingtin can also interact with a helper complex (the assistant chef from our analogy).

The more we understand about how the normal and extra-long huntingtin proteins are made and work in brain cells, the better equipped we'll be in the search for HD treatments.

Not exact matches

It's the extra-long copy of the huntingtin gene that makes neurons sick, because it causes them to produce an extra-long, harmful version of the huntingtin protein.

In HD, a repeated sequence of letters in this gene leads to an extra-long form of huntingtin protein that can wreak havoc in brain cells over long periods of time.

Since the helper complex mostly interacts with the extra-length huntingtin instructions, interfering with it should reduce translation of the extra-long variety.

Everyone has two copies of the huntingtin gene but Huntington's disease is caused by a copy that's extra-long.

If we could do it in people, it'd mean that extra-long or «mutant» huntingtin would never even have a chance to make neurons sick.

As expected, they found that the normal and extra-long genetic instructions were both translated into huntingtin proteins when they met up with a ribosome (the chef from our analogy above).