For a long time, we have known that regularly monitoring eye health is critical for identifying
eye disease at an early stage.
Ann Arbor, MI — Scientists at the University of Michigan have shown that their new metabolic imaging instrument can accurately detect
eye disease at a very early stage.
Not exact matches
Through his efforts
at General Hospital the
eye clinic was modernized and an
eye disease diagnosis service established.
We were given a list of possible donors, which gave us information on heritage, height,
eye color, occupation
at time of donation, blood type, and if the donor had a history of sexually transmitted
diseases.
Ophthalmology (New England
Eye Center)
at Floating Hospital for Children
at Tufts Medical Center specializes in the testing and treatment of all types of
eye diseases and visual problems.
People with Type 2 diabetes who have trouble sleeping are more
at risk of
eye disease, foot problems and amputation according to two new studies.
More than half a million ¹ people with diabetes in England are
at increased risk of blindness because they have not received retinal screening2, an essential annual check which tests for
eye disease (diabetic retinopathy).
Researchers performed liquid biopsies: A small amount of intraocular fluid was extracted from eight
eyes of members of the same family
at various stages of NIV and, as a control, four
eyes with a noninflammatory
eye disease.
Demonstrating the potential of precision health, a team led by a researcher
at the Stanford University School of Medicine has matched existing drugs to errant proteins expressed by patients with a rare
eye disease.
Mice with this
eye disease, which damages the optic nerve and causes vision loss, have higher levels of the immune molecule, which accumulates
at retinal synapses before the neurons die.
«While we do not know the exact role of sunlight in several
eye diseases, we now have a biomarker (iris freckles) indicating high amounts of chronic sunlight exposure,» says author Christoph Schwab, MD, ophthalmologist
at the Medical University of Graz, Austria.
Too few patients with retinal infarction, or loss of blood flow in the
eye, are evaluated for stroke risk or seen by a neurologist, putting them
at increased risk for another stroke, according to preliminary research presented
at the American Stroke Association's International Stroke Conference 2018, a world premier meeting dedicated to the science and treatment of cerebrovascular
disease for researchers and clinicians.
This synthetic
eye could be used to study and test treatments for
eye diseases, researchers reported February 16 in a news conference
at the annual meeting of the American Association for the Advancement of Science.
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that age (or age
at diagnosis) and duration of diabetes
disease are linked to the risk of death and marcovascular complications (those in larger blood vessels), whereas only diabetes duration is linked to the risk of microvascular complications (in smaller blood vessels such as those in the
eyes).
To work out how this might cause AMD, Paul Bishop
at the University of Manchester, UK, and colleagues applied normal and
diseased forms of CFH to macula obtained from donated
eyes.
LCA is a rare inherited
eye disease that destroys vision by killing photoreceptors — light - sensitive cells in the retina
at the back of the
eye.
After all, screening people
at high risk of developing the chronic
eye disease had been common practice for decades.
Dr Schneck and coauthors add, «The most common age - related
eye diseases (glaucoma, age - related macular degeneration, and diabetic
eye disease) all produce blue - yellow color vision anomalies,
at least in the preclinical or early stages.»
They look
at this «H+E stained» sample under a microscope and then judge the severity of the
disease by
eye alone.
Mutations in
at least 60 genes are known to cause the
disease, and many people are not diagnosed until after a a substantial proportion of photoreceptor cells, the
eye's rods and cones, have already degenerated and died.
«This provides strong evidence that Müller glia are important therapeutic targets for treating degenerative
eye diseases,» said Sehwon Koh, Ph.D., who is the lead author of this paper and a postdoctoral fellow in the laboratory of Cagla Eroglu, Ph.D., an associate professor of cell biology and neurobiology
at the Duke University Medical Center.
Dr Tariq Aslam, Senior Lecturer in Ophthalmology
at The University of Manchester, Consultant Ophthalmologist,
at Central Manchester University Hospitals NHS Foundation Trust (CMFT), and lead author of the study, said: «There have been amazing scientific achievements in diagnosing and treating serious
eye diseases, such as wAMD, which have revolutionised our ability to reverse life - changing vision loss.
Mary Elizabeth Hartnett, MD, and colleagues
at the John A. Moran Center and Department of Pediatrics
at the University of Utah and Children's Hospital of Wisconsin, were looking for a way to tease apart the effects of preeclampsia on the risk of developing retinopathy of prematurity (ROP), an
eye disease found in premature infants.
At least 50 % of patients with Graves»
disease, an autoimmune
disease that primarily attacks the thyroid gland, develop
eye problems including inflammation, discomfort, scarring, and bulging
eyes.
Early in the
disease, people can manage their symptoms by pointing a hairdryer
at their
eyes at arm's length to accelerate drying the corneal surface.
Participants included 10 people with post-treatment Lyme
disease syndrome (PTLDS); 10 who had high levels of an antibody against B. burgdorferi after antibiotic treatment; five who had erythema migrans (a bull's -
eye rash) and had received antibiotic treatment in the past; one person with erythema migrans who began antibiotic therapy
at the time of tick placement; and 10 healthy volunteers.
One in 10 Americans have diabetes, putting them
at heightened risk for visual impairment due to the
eye disease diabetic retinopathy.
Those tests don't give us the details we need to understand the nature of the pathology
at the cellular level, so we modeled the
disease to perform a systematic analysis of the optic nerve, from its origin in the
eyes to termination in the brain.»
Eye injections of the drug Avastin, used to treat retinal
diseases, bring no greater risk of endophthalmitis, a potentially blinding
eye infection, than injections with the much more expensive drug Lucentis made by the same company, according to new research from the Perelman School of Medicine
at the University of Pennsylvania.
«The PHPN offers a bird's
eye view of the
diseases and phenotype's relationships
at the systems level,» said Christian Darabos, PhD, post-doctoral fellow, Institute for Quantitative Biomedical Sciences (iQBS), Dartmouth College.
Nathans is a neuroscientist who studies how cells in the retina — the light - absorbing structure
at the back of the
eye, which is considered part of the brain — assume their correct identities, and how those cells respond to injury and
disease.
Researchers led by investigators Jerry Workman, Ph.D. and Susan Abmayr, Ph.D.
at the Stowers Institute for Medical Research found that fruit flies that lack Ataxin - 7 experience neurodegeneration in the brain and the
eye — paralleling the effects of the human
disease.
The study, from researchers involved with the nationwide SEARCH for Diabetes in Youth Study, looked
at five health complications and co-morbidities of diabetes, including: retinopathy (
eye disease), diabetic kidney
disease, peripheral neuropathy (altered sensation in the feet), arterial stiffness and high blood pressure.
It's also crucial that physicians remind patients that,
at this time, vitamins have yet to be proven clinically effective in preventing the onset of
eye diseases such as cataracts and AMD.»
Early signs of Lyme
disease include a distinctive circular «bulls -
eye» rash
at the site of the tick bite around three to 30 days after being bitten, although only one in three people develop this rash.
A link between cholesterol and an
eye disease might sound strange, but scientists have known for years that cholesterol can accumulate
at the back of the
eye as part of aging.
During his career, Dr. Aiello has received numerous awards, including sharing the 2014 Antonio Champalimaud Vision Award with Dr. George L. King
at Joslin for their contributions toward the discovery of treatments inhibiting vascular endothelial growth factor (VEGF) for diabetic
eye disease.
Thus, the proposed work directly tackles the mechanosensitive
disease mechanism in the posterior
eye but also aims
at developing new neuroprotective strategies.
If these results are confirmed in a larger trial, they will help to change how diabetic
eye disease is evaluated and treated, says Paolo Silva, M.D., staff ophthalmologist and assistant chief of telemedicine
at Joslin's Beetham
Eye Institute.
Research in the lab of Edward P. Feener, Ph.D., Investigator in the Section on Vascular Cell Biology and Director of the Proteomics Core
at Joslin Diabetes Center and an Associate Professor of Medicine
at Harvard Medical School, now has shown that a substantial percentage of patients with DME do not have high levels of VEGF in the fluid inside their
eyes but do have high levels of a protein called PKal (plasma kallikrein) and associated molecules that are key players in an inflammatory molecular pathway involved in the
disease.
Following graduation, Bakina will be pursuing a Ph.D.
at Helmholtz Zentrum in Munich, Germany, working alongside professor Joachim Graw, Ph.D., investigating molecular
eye disease within the Institute of Developmental Genetics.
Back when stem cells were first extracted from human embryos 20 years ago, scientists were fascinated
at their ability to change into any type of cell in the body and thought they would soon be used to treat all types of
diseases, from
eye disorders to diabetes.
Virginia Tech researchers successfully used a gene disruption technique to change the
eye color of a mosquito — a critical step toward new genetic strategies aimed
at disrupting the transmission of
diseases such as dengue fever.
Scientists
at the Hopkins School of Medicine's Center for Sensory Biology now have a greater understanding of the workings of the fruit fly's
eye, an understanding that may one day help human patients suffering from degenerative
diseases of the retina.
«In a report published in the journal Lancet, scientists led by Dr. Robert Lanza, chief scientific officer
at Advanced Cell Technology, provide the first evidence that stem cells from human embryos can be a safe and effective source of therapies for two types of
eye diseases»
Inclusion Criteria: • Availability of tumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic
disease (tumour type specific inclusion criteria) •
At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any
eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion criteria
May 31, 2000 $ 250,000 gift supports children's
eye care
at University of Chicago Hospitals A generous gift of $ 250,000 from Chicago real estate developer Dempsey J. Travis will support the opening of the Dempsey and Moselynne Travis Pediatric
Eye Clinic, a specialty center devoted to prevention, diagnosis and treatment of children's
eye disease.
They are seeking ways to target the
disease at its earliest stages, so that innovative treatments might be developed to significantly delay
disease progression even in patients who do not respond to current medical and surgical treatments that only lower pressure in the
eye.
2018 video research update from the Dubra Laboratory
at Stanford University School of Medicine; the main goal of the Dubra lab is to develop non-invasive optical imaging methods for early detection and monitoring of
eye disease.
«Given the high prevalence and progressive nature of neovascular
eye disease, the ability to stabilize bioactive lipids that mitigate or halt
disease is of great and increasingly therapeutic significance,» said corresponding author and RPB grantee Kip Connor, PhD, a vision scientist
at Mass..