Sentences with word «ezetimibe»

This was the issue in last winter's congressional investigation into the nonstatin cholesterol - lowering drug ezetimibe, sold as Zetia and contained in Vytorin.

Efficacy and Tolerability of Evolocumab vs Ezetimibe in Patients With Muscle - Related Statin Intolerance.

Stein E. Results of phase I / II clinical trials with ezetimibe, a novel selective cholesterol absorption inhibitor.

Statins block cholesterol made in the liver, while ezetimibe blocks the absorption of cholesterol in the gut.

This approximately 10 percent reduction in LDL cholesterol is comparable to that seen in patients taking ezetimibe.

While ezetimibe is known for its cholesterol - lowering effect, there is debate over whether it also reduces risk of heart disease.

Whether ezetimibe specifically is the best way to target NPC1L1 remains an open question.»

«It's not possible to draw a direct conclusion about ezetimibe from this study,» Stitziel said.

Hearings in January revealed that the release of negative results of a clinical trial of ezetimibe had been delayed.

Davis HR, Compton DS, Hoos L, and Tetzloff G. Ezetimibe, a Potent Cholesterol Absorption Inhibitor, Inhibits the Development of Atherosclerosis in ApoE Knockout Mice.

(Ezetimibe on its own is sold under the name Zetia, which was first approved in 2002.)

Fluvastatin = Lescol, Lescol XL Lovastatin = Mevacor, Altocor Mevastatin Pitavastatin = Livalo, Pitava Pravastatin = Pravachol, Selektine Rosuvastatin = Crestor Simvastatin = Zocor, Lipex Simvastatin + Ezetimibe = Vytorin Lovastatin + Niacin extended - release = Advicor Atorvastatin + Amlodipine Besylate = Caduet How Do Statin Drugs Work?

Ezetimibe works in a different way from statins.

Inegy combines the widely - used statin drug simvastatin with a new medication called ezetimibe.

Vytorin is a related pill that combines Zetia (generically known as ezetimibe) with Zocor (simvastatin).

The gene, called NPC1L1, is of interest because it is the target of the drug ezetimibe, often prescribed to lower cholesterol.

Against a background therapy of statins (73 %), alone or with ezetimibe (31 %), the time averaged reductions in LDL cholesterol at one year with a single dose of 200, 300 or 500 mg inclisiran were -31.6 %, -38.1 % and -39.8 %, respectively.

Instead, ezetimibe blocks dietary cholesterol absorption in the gut by inhibiting the NPC1L1 protein, perhaps approximating the effect of having only one working copy of the NPC1L1 gene.

Taking ezetimibe (Zetia) before a PCSK9 inhibitor, a different class of cholesterol - busting drugs, bile acid sequestrants (BAS), or fibric acid medications can also lower LDL cholesterol; these drugs are not linked to adverse muscle complaints.

It's more effective than fellow cholesterol - lowering medications, ezetimibe and statin.

The trial was designed to compare outcomes — such as cardiovascular - related death and heart attack — in patients taking a statin plus ezetimibe versus patients taking a statin plus placebo.

Together, ezetimibe plus statins have been shown to lower LDL cholesterol more than statins alone.

ORLANDO, Fla. — Adding a pharmaceutical form of the B vitamin niacin — but not the drug ezetimibe — to a cholesterol - lowering statin drug appears to reduce artery plaque buildup in patients with coronary artery disease, according to much - anticipated results announced at a press conference November 15.

The results were from a study that was relatively small — only 208 patients — but provided a head - to - head comparison of niacin and ezetimibe, known by the brand name Zetia.

Among medications that lower cholesterol, ezetimibe is not in the widely prescribed class of drugs called statins, which stop the body from manufacturing its own cholesterol.

While manufacturers Merck and Schering - Plough delayed the negative study's release for more than 18 months, ezetimibe had turned into a blockbuster drug, even though it had never been shown to reduce heart attacks or deaths.

Ezetimibe: a selective inhibitor of cholesterol absorption.

The trial found that the drug — a combination of a relatively new medication, ezetimibe, and an older statin drug, simvastatin (Zocor)-- was no more effective than simvastatin alone for treating patients with high cholesterol.

According to Wikipedia, the standard of care drugs are Ezetimibe (prevents reabsorption of sterols in the intestines) and bile salts like Colestipol and Colestyramine (that's Questran — might be better for you than one of the other drugs).

Development and Validation of Chiral HPLC Method for Identification and Quantification of (R)- Enantiomer in Ezetimibe