Subscales derived from
factor analysis include economic burden, family / social impact, personal strain, and mastery; however, only the Total scale score (internal consistency reliability =.88; Stein & Riessman, 1980) was used in the current study.
Not exact matches
The demographic data firm Sperling's BestPlaces based its predictions on
factors including cost of living, access to transportation, infrastructure, and education, updating its
analysis as the e-commerce giant continues to tease new information about the massive project called HQ2.
In each
analysis, we controlled for other risk
factors for the outcome,
including smoking, obesity, and comorbid conditions.
According to an
analysis of 2010 data by the Urban Institute, a nonpartisan think tank, the price tag was $ 669 million in direct hospital costs for just that year and $ 174 billion in larger societal costs, which
includes disability, effects on employment, and other longer - term
factors.
It doesn't
include security related to air travel, so if a CEO is required to fly on the corporate jet for safety reasons — even for personal travel — that cost is not
factored into Equilar's
analysis of a company's overall CEO security spending.
More information regarding potential risks and other
factors that could affect Apple's financial results is included in Apple's filings with the SEC, including in the «Risk Factors» and «Management's Discussion and Analysis of Financial Condition and Results of Operations» sections of Apple's most recently filed periodic reports on Form 10 - K and Form 10 - Q and subsequent f
factors that could affect Apple's financial results is
included in Apple's filings with the SEC,
including in the «Risk
Factors» and «Management's Discussion and Analysis of Financial Condition and Results of Operations» sections of Apple's most recently filed periodic reports on Form 10 - K and Form 10 - Q and subsequent f
Factors» and «Management's Discussion and
Analysis of Financial Condition and Results of Operations» sections of Apple's most recently filed periodic reports on Form 10 - K and Form 10 - Q and subsequent filings.
Important
factors that could cause our actual results and financial condition to differ materially from those indicated in the forward - looking statements include, among others, the following: our ability to successfully and profitably market our products and services; the acceptance of our products and services by patients and healthcare providers; our ability to meet demand for our products and services; the willingness of health insurance companies and other payers to cover Cologuard and adequately reimburse us for our performance of the Cologuard test; the amount and nature of competition from other cancer screening and diagnostic products and services; the effects of the adoption, modification or repeal of any healthcare reform law, rule, order, interpretation or policy; the effects of changes in pricing, coverage and reimbursement for our products and services, including without limitation as a result of the Protecting Access to Medicare Act of 2014; recommendations, guidelines and quality metrics issued by various organizations such as the U.S. Preventive Services Task Force, the American Cancer Society, and the National Committee for Quality Assurance regarding cancer screening or our products and services; our ability to successfully develop new products and services; our success establishing and maintaining collaborative, licensing and supplier arrangements; our ability to maintain regulatory approvals and comply with applicable regulations; and the other risks and uncertainties described in the Risk Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10 - K and our subsequently filed Quarterly Reports on Form
factors that could cause our actual results and financial condition to differ materially from those indicated in the forward - looking statements
include, among others, the following: our ability to successfully and profitably market our products and services; the acceptance of our products and services by patients and healthcare providers; our ability to meet demand for our products and services; the willingness of health insurance companies and other payers to cover Cologuard and adequately reimburse us for our performance of the Cologuard test; the amount and nature of competition from other cancer screening and diagnostic products and services; the effects of the adoption, modification or repeal of any healthcare reform law, rule, order, interpretation or policy; the effects of changes in pricing, coverage and reimbursement for our products and services,
including without limitation as a result of the Protecting Access to Medicare Act of 2014; recommendations, guidelines and quality metrics issued by various organizations such as the U.S. Preventive Services Task Force, the American Cancer Society, and the National Committee for Quality Assurance regarding cancer screening or our products and services; our ability to successfully develop new products and services; our success establishing and maintaining collaborative, licensing and supplier arrangements; our ability to maintain regulatory approvals and comply with applicable regulations; and the other risks and uncertainties described in the Risk
Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10 - K and our subsequently filed Quarterly Reports on Form
Factors and in Management's Discussion and
Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10 - K and our subsequently filed Quarterly Reports on Form 10 - Q.
So today what is needed is an extension of the old mosaic to
include, in addition to all the financial
analysis which is still valid, material non-financial
factors, and shared value.
To date, results from several longitudinal studies indicate that e-cigarette use among nonsmoking youth increases the likelihood of future use of conventional cigarettes.5 — 10 Specifically, the pooled odds ratio (OR) in a recent meta -
analysis of studies of adolescents and young adults (aged 14 — 30) indicates that those who had ever used e-cigarettes were 3.62 times more likely to report using cigarettes at follow - up compared with those who had not used e - cigarettes.11 This finding was robust and remained significant when adjusting for known risk
factors associated with cigarette smoking,
including demographic, psychosocial, and behavioral variables such as cigarette susceptibility.
You should read the following summary together with the more detailed information appearing in this prospectus,
including «Selected Consolidated Financial Data,» «Management's Discussion and
Analysis of Financial Condition and Results of Operations,» «Risk
Factors,» «Business» and our consolidated financial statements and related notes before deciding whether to purchase shares of our capital stock.
You should read the following summary together with the more detailed information appearing in this prospectus,
including «Risk
Factors,» «Selected Consolidated Financial Data,» «Management's Discussion and
Analysis of Financial Condition and Results of Operations,» «Business» and our consolidated financial statements and related notes before deciding whether to purchase shares of our Class A common stock.
As described, a request for payment would be sent to the blockchain - based system, which would either be approved or rejected based on various
factors,
including a risk
analysis.
The global political environment is an important
factor for Canadians» attitudes to a Canada - China FTA.Three variables pertaining to the global political environment were
included for
analysis:
In our statistical
analysis, we
include all of the confounding
factors discussed above, and control for demographic and regional differences in order to tease out the effects of different
factors on whether Canadians support, oppose, or have no opinion about an FTA with China.
More information on these risks and other potential
factors that could affect the Company's financial results is included in the Company's filings with the SEC, including in the «Risk Factors» and «Management's Discussion and Analysis of Financial Condition and Results of Operations» sections of the Company's most recently filed periodic reports on Form 10 - K and Form 10 - Q and subsequent f
factors that could affect the Company's financial results is
included in the Company's filings with the SEC,
including in the «Risk
Factors» and «Management's Discussion and Analysis of Financial Condition and Results of Operations» sections of the Company's most recently filed periodic reports on Form 10 - K and Form 10 - Q and subsequent f
Factors» and «Management's Discussion and
Analysis of Financial Condition and Results of Operations» sections of the Company's most recently filed periodic reports on Form 10 - K and Form 10 - Q and subsequent filings.
Measures of financial stability
include the ability to sustain current dividend payments from earned net income, adequacy of working capital, ability to service debt from earned cash flows, stability of profit margins,
analysis of price behavior, and other
factors.
Looking at the varied interplay of these
factors makes for a powerful and very successful sociological
analysis that can be applied to many situations — businesses, churches, (
including dioceses and parishes) as well as clubs, movements and whole nation states.
Higher criticism
includes an
analysis of the literary genre of the text, its historical background, the history of the oral tradition behind the text, and the cultural and psychological
factors at work on the author and editor (or editors) of the text.
The
analysis controlled for other
factors that typically influence levels of religiosity,
including age, gender, race and ethnicity, region, state, socioeconomic status, marital status and child - bearing status.
For the recent competition, submissions were evaluated blind and through organoleptic
analysis of characteristics,
including flavor, body, color, clarity and balance (leaf appearance was not a
factor).
In an
analysis of SIDS deaths in Chicago, researchers controlled for various SIDS risk
factors,
including maternal smoking, soft sleep surface, pillow use, prone sleep position, and pacifier use.
* Pregnancy risk status was
included in the multivariable
analysis via the inclusion of a number of individual risk
factors as model covariates (see «Definitions» section and Table 3).
Although the «best interest» standard does vary from state to state, some
factors are common in the best interest
analysis used by the individual states,
including:
Ideally, a good answer would
include some sort of regression
analysis to show which of the grouping
factors correlate and / or predict net worth best.
Some methodological issues addressed by this project
include: data provenance; quality control in data collection and
analysis; representativeness of the collected data; and potential data gaps due to
factors such as gender and access to technology.
This article uses GIS and
factor analysis of land resources to explore the success of resettlement programs for economically disadvantaged mountain dwelling populations in China,
including the selection of suitable resettlement sites.
Various confounding
factors including diet quality and sleep length were controlled for in the
analyses.
In addition to environmental variability and lack of treaties, other
factors leading to conflict
include political and economic instability, and armed conflict, the
analysis shows.
This difference was independent of other heart disease risk
factors including age, gender, family history, education level, body mass index, smoking habits, hypertension, diabetes and high cholesterol, all of which the researchers adjusted for in their
analysis.
«During brushing with these toothpastes mixed with artificial saliva, we found that the properties of the toothpastes were different, so we decided to broaden the scope of the
analysis to
include chemical and physical
factors.
And further
analyses revealed that the classroom improvement effect was not influenced by various individual - and classroom - level
factors,
including student race, student intervention condition, and teacher team, in either study.
Women's heart disease risk was more than doubled with one cigarette per day, when only studies that controlled for several
factors were
included in the
analysis.
«Our
analysis of three large U.S. cohorts
including persons in whom diabetes has been diagnosed shows those who were at target levels for HbA1c, blood pressure and LDL to have substantially lower risks for cardiovascular disease than persons with diabetes who were not at target levels for such
factors,» Wong said.
Venkateswaran agrees that they need to do more work to assess whether any dangerous pathogens are lingering in the ISS, which they hope to do by isolating intact bacteria and looking for virulence
factors, increasing the length of the DNA chains they can sequence, and expanding their
analyses to
include viruses.
Several possible
factors that could influence the statistical
analysis were taken into account
including age, birth weight and sex of the baby.
A multivariable
analysis that
included factors such as age, sex, stage, disease burden, certain mutations and prior treatment showed that obesity still improved PFS and OS compared to normal BMI patients.
In
analyses adjusting for known risk
factors for diabetes,
including age, sex, body mass index, neck circumference, smoking, income status and comorbidities at baseline, patients with an AHI > 30 had a 30 % higher risk of developing diabetes than those with an AHI < 5.
The statistical
analysis took into consideration
factors including maternal age and race, smoking history, and body mass index (BMI).
Various confounding
factors including diet quality, body fat percentage and sleep length were controlled for in the
analyses.
Detailed
analyses of this information may lead to a better understanding of the nonstorm - related
factors that influence surges,
including the slope of the seafloor immediately offshore, says Katie McDowell Peek, a member of the Western Carolina team.
Dr Larkin said: «Results from our large
analysis of pre-defined sub-groups of patients with advanced melanoma provide evidence that suggests the combination of the two drugs consistently improves progression - free survival across a range of sub-groups,
including patients with poor prognostic
factors, when compared with either nivolumab or ipilimumab alone.»
Many functional categories of genes were represented in these
analyses,
including calcium signaling, cytokines, and growth
factor pathways.
Future
analyses of these databases
include assessing the postoperative revisit rates of patients undergoing septorhinoplasty, as well as the risk
factors and primary diagnosis associated with these revisits.
In multivariate
analyses that
included clinical
factors, BRCA2 / ATM, TP53, and PI3K pathway alterations remained significantly associated with shorter time to progression.
Diabetes as a risk
factor for stroke in women compared with men: a systematic review and meta -
analysis of 64 cohorts,
including 775,385 individuals and 12,539 strokes
Subgroup
analyses showed trends or significant overall survival improvements for all subgroups measured,
including by disease stage, ECOG score, age, and other
factors.
We used a bioninformatics
analysis to identify that miR - 181a targets components of the bone morphogenetic protein (BMP) signalling pathway,
including the transcription
factors Smad1 and Smad5, which we find are expressed by rat mDA neurons and are required for BMP - induced neurite growth.
Comparative
analysis enabled by the sequencing of the sponge genome reveals genomic events linked to the origin and early evolution of animals,
including the appearance, expansion and diversification of pan-metazoan transcription
factor, signalling pathway and structural genes.
Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional
analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting
Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants
including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs
including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters
Furthermore, we discuss key experimental design considerations,
including the choice of the method used to determine metastatic burden and statistical
analysis of the results, as well as provide troubleshooting tips and identification of
factors that contribute to experimental variability.