Sentences with phrase «factor gene promoter»

Early life adversity and serotonin transporter gene variation interact to affect DNA methylation of the corticotropin - releasing factor gene promoter region in the adult rat brain

Not exact matches

Experiments proved that Heat Shock Factor 1 (HSF1), a sort of protective switch against some types of cellular stress, could bind to the TTR gene's promoter (a segment of DNA near the TTR gene).

Hockemeyer says that it's unlikely to be another mutation, but rather an epigenetic change that affects expression of the telomerase gene, or a change in the expression of a transcription factor or other regulatory proteins that binds to the promoter upstream of the telomerase gene.

The protein, HSF - 1 (heat shock factor - 1), does this by binding to promoters upstream of the 350 - plus chaperone genes, upping the genes» activity and launching the army of chaperones, which originally were called «heat shock proteins.»

When a given gene needs to be transcribed to create new proteins, its promoter region must be unwrapped from the nucleosome so that it can be accessed by the factors involved in initiating the transcription process.

The researchers found that the AD risk factor ApoE4 bound to promoters of 1,700 genes that ApoE3 did not.

Sp1 binds to the GC - rich sequence on the proximal region of p21waf1 / cip1 promoter and acts as a mediator for the induction of p21waf1 / cip1 gene caused by transforming growth factor β (TGF - β; ref.

The researchers found that portions of the FTO gene were involved in switching on a promoter of IRX3, which encodes a transcription factor and is highly conserved in mice, zebrafish, and humans.

The group of promoters, whose H3K4me3 levels were affected by combined chidamide and decitabine treatment, but not by either chidamide or decitabine treatment alone, was enriched with binding site motifs for PU.1, a transcription factor that activates gene expression during myeloid and B - cell lymphoid cell development15, 16 (Figure 5C).

Research Interests: RNA synthesis; RNA polymerase; promoter; general transcription factors; gene expression; gene regulation; chromatin structure and gene regulation

Besides, some other potential cis - acting elements for transcription factors [such as CAAT / enhancer binding protein (C / EBP) and PU.1] have been also noted in the RIG - G gene promoter.

Peak finding and annotation to the nearest RefSeq gene promoter was performed using HOMER (findPeaks program using the «- style factor» option).