Transcription -
factor genes code for proteins that regulate the activity of other genes and so affect an animal's ability to respond to its environment.
Not exact matches
The OAR proposal uses a variation of therapeutic cloning called altered nuclear transfer (ANT) in which the nucleus of a donor cell (a skin cell, for example), containing the 30,000
genes of the genetic
code, is altered in such a way that it produces an epigenetic
factor, a protein called nanog.
For nearly two decades,
gene therapy researchers have focused on delivering a
gene carrying the
code to produce the deficient clotting
factor in hemophilia.
One of the
genes most often associated with anorexia nervosa
codes for BDNF, a
factor involved in neuron survival and neuroplasticity.
Environmental
factors can modify DNA and lead to heritable changes in the way that
genes are expressed — even though the genetic
code itself is unchanged.
Another connects post-traumatic stress disorder to methylation of the
gene coding for neurotrophic
factor, a protein that regulates the growth of neurons in the brain.
Affected family members, the group found, had inherited one or two defective copies of ZIC3, a previously unknown
gene that appears to
code for a transcription
factor — a protein that switches other
genes on or off.
Working with cultures of respiratory tract cells, Elias's team found that the
gene that
codes for il - 6 is inactive unless a protein known as nf - kb (nuclear
factor - kappa beta) attaches to the
gene.
The
gene (E2A) that
codes for proteins with the properties of immunoglobulin enhancer binding
factors E12 / E47 was mapped to chromosome region 19p13.2 - p 13.3, a site associated with nonrandom translocations in acute lymphoblastic leukemias.
All of these
genes code for transcription
factors, which are proteins that control the expression of other
genes.
The
gene codes for a type of protein called a transcription
factor.
Naturally, every
gene is not regulated by its own distinct transcription
factor; otherwise, a codebook of as many as 30,000
genes would require 30,000 transcription
factors — and 30,000 more
genes to
code for them.
When the chimp and human genomes are compared, some of the clearest cases of nucleotide differences are found in
genes coding for transcription
factors.
In addition to looking at transcription
factors, researchers have studied the
genes that
code for the enzymes responsible for building up the plant's biomass.
The
genes for each transcription
factor were made from different bits of DNA that
code for the functional parts of proteins, such as a domain that can bind to DNA and another that provides the protein with access to the cell's nucleus.
The
gene - by - hormone interaction's effect on circuit function was found only with one of two versions of the
gene that
codes for BDNF (brain - derived neurotrophic
factor), a chemical messenger operating in the circuit.
Both
genes code for proteins that function as growth
factor receptors, meaning they sit on the surface of cells and, when activated, can spur the rapid cell growth that is a hallmark of cancer.
The team suspects the difference may be due to the expression of a
gene that
codes for a growth
factor called bone morphogenetic protein 2 (Bmp2); expression was 30 % higher in the developing forelimbs of bats than it was in mice.
The branch uniting the fungi and animals is well - supported based on a number of molecular phylogenetic datasets, including the nuclear small subunit ribosomal RNA
gene (Wainwright et al., 1993; Bruns et al. 1993), unique and shared sequence insertions in proteins such as elongation
factor 1α (Baldauf and Palmer, 1993), entire mitochondrial genomes (Lang et al., 2002), and concatenated protein -
coding genes (Steenkamp et al., 2006).
Other genetic diseases include Tay - Sachs disease (damage to the
gene for the enzyme hexosaminidase A leads to an accumulation of a chemical in the brain that destroys it), sickle cell anemia (improper
coding of the
gene that produces hemoglobin), hemophilia (lack of a
gene for a blood - clotting
factor) and muscular dystrophy (caused by a defective
gene on the X chromosome).