Not exact matches
That's not just because of Opdivo's
failure — last month, Keytruda was shown to be better
than standard chemotherapy in untreated advanced lung cancer
patients with high levels of the PD - L1 protein, both stopping cancer progression and extending
patients» lives.
A study in 2011 looking at more
than 645 ACL surgeries found that in
patients between the ages of 10 ««19, allograft tissue had a four times higher
failure rate
than using your own tissue.
Twenty
patients with kidney
failure, for example, showed levels of ammonia and acetone more
than 10 times that of healthy controls, and the researchers could watch those levels fall back to normal as the
patients received dialysis treatment.
Studies have shown that when doxorubicin is administered slowly, rather
than all at once,
patients may have a lower risk of heart
failure.
«Heart
failure patients fare better with catheter ablation
than Amiodarone.»
Among black kidney
failure patients undergoing dialysis, women are much less likely
than men to want to receive kidney transplants from living donors, despite more offers from family and friends.
Amit Patel, a cardiac surgeon and researcher at the University of Pittsburgh, has completed three clinical trials in Asia and South America that included more
than 100 heart -
failure patients.
They found that
patients from this group who required admission to intensive or critical care units after surgery were more likely to have a history of chronic obstructive pulmonary disease, congestive heart
failure, coronary artery disease, chronic kidney disease, or suffering blood loss of more
than 1,000 milliliters during surgery or requiring vasopressors (medications that raise low blood pressure) during surgery.
Researchers found moderate sedation was primarily used to calm anxiety in more
than half of the
patients (54 percent), followed by fear of needles (15 percent), local anesthesia
failures (15 percent) and severe gag reflex and claustrophobia from the rubber dam (both 8 percent).
However, the results suggest that personal factors for each
patient appear to influence their chance of filling
failure, rather
than the filling material their dentist used.
«Dental filling
failure linked to smoking, drinking and genetics: A new study suggests that personal
patient factors influence the chance of dental filling
failure, rather
than the choice of filling material.»
Hospitalized heart
failure patients in all age groups within the study and with all levels of ejection fraction had significantly lower rates of survival after five years and a higher risk of re-hospitalization
than people in the United States without heart
failure.
Tests in mice and nonhuman primates had shown TGN1412 to be safe, but when it was injected into humans — in a dose less
than 1/500 of what was given to monkeys — it caused a massive release of infection - fighting T cells that overstimulated the
patients» immune systems, resulting in multiple organ
failure.
To investigate, Csaba Kovesdy, MD (Memphis VA Medical Center and the University of Tennessee Health Science Center) and his colleagues examined information from the national VA research database and looked for associations between blood pressure and various clinical outcomes — coronary heart disease, stroke, kidney
failure, and death — in more
than 300,000
patients with CKD.
At the convention Nitromed officials discussed the results of a new BiDil trial, entailing more
than 1,000 African American
patients with heart
failure.
Borja Ibáñez — joint lead investigator on the study with Valentín Fuster — explains that «the possibility to reduce so dramatically the number of cases of chronic heart
failure (with all the associated treatments and hospital readmissions) with such a cheap procedure (the metoprolol treatment costs less
than two euros per
patient) could generate enormous savings for health services across Europe.»
The results showed that a significantly lower proportion of different bacteria are found in the gut in
patients with heart
failure than in healthy controls.
The researchers also analyzed the effects of methylnaltrexone on another 135
patients from the same trials who had advanced illnesses other
than cancer, such as congestive heart
failure, advanced chronic obstructive pulmonary disease or neurologic diseases.
Patients with a history of breast cancer or lymphoma were more than three times as likely to develop heart failure — a condition in which the heart can't pump enough blood to meet the body's needs — compared with a similar group of patients who did not have cancer, according to data being presented at the American College of Cardiology's 67th Annual Scientific
Patients with a history of breast cancer or lymphoma were more
than three times as likely to develop heart
failure — a condition in which the heart can't pump enough blood to meet the body's needs — compared with a similar group of
patients who did not have cancer, according to data being presented at the American College of Cardiology's 67th Annual Scientific
patients who did not have cancer, according to data being presented at the American College of Cardiology's 67th Annual Scientific Session.
Instead, the study showed that Medicaid
patients and individuals with comorbid illnesses had longer stays
than other heart -
failure patients.
More
than 1 million hospitalizations for heart
failure (HF) occur annually in the United States alone, and more
than 80 percent of these hospitalized
patients have worsening chronic HF.
For example,
failure to intensify therapy in hypertensive
patients with blood pressure greater
than 140/90 has been reported to be as high as 86.9 % of visits.
Using data from a United Kingdom database known as The Health Improvement Network (THIN), researchers extracted health records of more
than 12,000
patients ages 55 and older who had Type 2 diabetes and heart
failure but no prior history of heart attack, stroke, peripheral artery disease or atrial fibrillation.
Results of one of the largest studies of heart
failure to date show that warfarin is no better
than aspirin in reducing the combined risks of brain hemorrhage, stroke and death in most heart
failure patients.
Bone marrow
failure disease
patients are at risk for developing iron overload if they have had more
than 20 units of packed red blood cells.
The use of minimal residual disease (MRD) provided a more objective measure of induction
failure in
patients with pediatric acute lymphoblastic leukemia (ALL)
than did morphology, according to the results of a study published recently in the Journal of Clinical Oncology.
«Using the tip of an atomic force microscope (AFM), we have found that the mechanical force required to break the bond between fibrinogen and erythrocytes is higher in
patients with chronic heart
failure than in healthy subjects,» explains team leader Nuno C Santos from iMM and the Faculty of Medicine at the University of Lisbon.
A large - scale metaanalysis on heart
failure, using a huge individual
patient dataset, found that diabetes was more frequent in women
than men, including
patients with both reduced and preserved ejection fraction (307).
But the damage caused by a heart attack can result in heart
failure — and
patients diagnosed with heart
failure have an average life expectancy of less
than five years, according to Dr. Chuck Murry, director of the Center for Cardiovascular Biology at the University of Washington in Seattle.
For example, more
than 20 million
patients have chronic heart
failure with at least 4 million admissions to hospital each year in the USA and Europe, and the size of this
patient population is actively growing.
In addition,
patients who received Rydapt in combination with chemotherapy in the trial went longer (median 8.2 months) without certain complications (
failure to achieve complete remission within 60 days of starting treatment, progression of leukemia or death)
than patients who received chemotherapy alone (median three months).
Enthusiasm for intralesional BCG therapy waned following reports of anaphylactic reactions; disseminated BCG mortality [7]; and, in our own research, the occurrence of punctate abscesses in more
than two - thirds of treated
patients, as well as
failure to impact outcomes.
At the other end of the spectrum, heart
patients who consumed very little sodium were also more likely
than those with average intake to die of heart disease or be hospitalized for heart
failure.
Another recent study found that more
than 7 % of all bypass
patients experience acute kidney
failure.
The images of the walls and valves of the heart produced by MUGA scans are more accurate and detailed
than the ultrasound images generated by an echocardiogram, especially in obese
patients, and are helpful in diagnosing heart
failure or heart valve disease.
These
patients suffer a worse quality of life
than those with most other chronic illnesses, including congestive heart
failure, diabetes, multiple sclerosis and arthritis.
Past research has shown that
patients with congestive heart
failure tend to have lower magnesium levels
than the general population.
For example, water drinking increases systolic blood pressure more
than 30 mm Hg in
patients with severe autonomic
failure.
In a 2012 report reviewing the effects of HIIT in
patients with coronary artery disease and heart
failure, researchers in Canada, France and Switzerland wrote that «HIIT appears safe and better tolerated by
patients than moderate - intensity continuous exercise» and more effective at increasing
patients» peak oxygen uptake, blood vessel flexibility and pumping ability of the heart.
Heart
failure patients tend to clear theophylline from their bodies more slowly
than normal
patients.
This could be a problem in
patients with congestive heart
failure or other
patients who require sodium restriction May stunt growth if used in young, growing animals May lower seizure threshold and alter mood and behavior At high doses, this medication can cause birth defects early in pregnancy, be irritating to the stomach or cause higher
than normal blood sugar levels If your pet has received high doses, it should not be vaccinated without your veterinarian's advice as the vaccine may not work or it may actually give your pet the disease you are trying to prevent Less common side effects include weight gain, insomnia, panting, diarrhea, vomiting, elevated liver enzymes, pancreatitis and behavior changes Serious side effects are not expected with routine use.
Patients that present in congestive heart
failure generally have a worse prognosis
than those that are not in congestive heart
failure at presentation.
Moreover, it is very important to remember
than the vast majority of
patients with cardiac disease will not develop heart
failure.
The biggest thing is making sure you can qualify for life insurance with SBLI, so lets cover (in general) what SBLI will and won't insure: SBLI Underwriting Uninsurable medical scenarios with SBLI: • Aids / HIV + status • ALS (Amyotrophic Lateral Sclerosis) • Alzheimer's disease or dementia or significant cognitive impairments related to functionality • Cancer diagnosis within last 2 years • Chronic pain treatment, severe, receiving disability, narcotic use • Cirrhosis of the Liver • Congestive heart
Failure • COPD / Emphysema or chronic bronchitis - Severe or with current nicotine use • Cystic Fibrosis • Defibrillator use • Depression, severe, recurrent or with multiple in - patient hospitalization history • Diabetes with co-morbidities that include significant cardiac disease, or impairment of renal function or mobility • Heart / Cardiac Disease - multiple vessels diagnosed within 2 years or any past history with current nicotine use • Muscular Dystrophy • Multiple Sclerosis, if symptoms progressing • Organ Transplants, in most scenarios • Quadriplegia • Pulmonary hypertension • Renal failure, Renal insufficiency - severe • Stroke within 1 year • Suicide attempt within 5 years • Surgical repair of heart valves, aneurysms, intracranial tumors, major organs within six months, including gastric bypass Uninsurable non-medical scenarios: • Marijuana use, 4 or more times weekly • Substance abuse / misuse within last 5 years • Criminal activity - any history within the last 10 years • DUI, more than 2 or under age 25 if within 1 year • Unemployed (other than homemakers or retired) with minimal household income or dependent on SSI / disability benefits • Bankruptcy filing within 2 years • Liens / Judgements - outstanding activity that exceed
Failure • COPD / Emphysema or chronic bronchitis - Severe or with current nicotine use • Cystic Fibrosis • Defibrillator use • Depression, severe, recurrent or with multiple in -
patient hospitalization history • Diabetes with co-morbidities that include significant cardiac disease, or impairment of renal function or mobility • Heart / Cardiac Disease - multiple vessels diagnosed within 2 years or any past history with current nicotine use • Muscular Dystrophy • Multiple Sclerosis, if symptoms progressing • Organ Transplants, in most scenarios • Quadriplegia • Pulmonary hypertension • Renal
failure, Renal insufficiency - severe • Stroke within 1 year • Suicide attempt within 5 years • Surgical repair of heart valves, aneurysms, intracranial tumors, major organs within six months, including gastric bypass Uninsurable non-medical scenarios: • Marijuana use, 4 or more times weekly • Substance abuse / misuse within last 5 years • Criminal activity - any history within the last 10 years • DUI, more than 2 or under age 25 if within 1 year • Unemployed (other than homemakers or retired) with minimal household income or dependent on SSI / disability benefits • Bankruptcy filing within 2 years • Liens / Judgements - outstanding activity that exceed
failure, Renal insufficiency - severe • Stroke within 1 year • Suicide attempt within 5 years • Surgical repair of heart valves, aneurysms, intracranial tumors, major organs within six months, including gastric bypass Uninsurable non-medical scenarios: • Marijuana use, 4 or more times weekly • Substance abuse / misuse within last 5 years • Criminal activity - any history within the last 10 years • DUI, more
than 2 or under age 25 if within 1 year • Unemployed (other
than homemakers or retired) with minimal household income or dependent on SSI / disability benefits • Bankruptcy filing within 2 years • Liens / Judgements - outstanding activity that exceeds $ 50K
Borderline personality disorder (BPD) is 1 of only 2 DSM - IV diagnoses for which suicidal behavior is a criterion.1 Borderline personality disorder is a severe and persistent mental disorder experience of severe emotional distress and behavioral dyscontrol.1 - 3 Among
patients with BPD, 69 % to 80 % engage in suicidal behavior,4 - 9 with a suicide rate of up to 9 %.10 Forty percent of the highest users of inpatient psychiatric services receive a diagnosis of BPD.11, 12 Patients with BPD use more services than those with major depression13 and other personality disorders.14 Among patients with BPD seen for treatment, 72 % have had at least 1 psychiatric hospitalization and 97 % have received outpatient treatment from a mean of 6.1 previous therapists.15, 16 Despite this high - use pattern, patients with BPD have high rates of treatment failur
patients with BPD, 69 % to 80 % engage in suicidal behavior,4 - 9 with a suicide rate of up to 9 %.10 Forty percent of the highest users of inpatient psychiatric services receive a diagnosis of BPD.11, 12
Patients with BPD use more services than those with major depression13 and other personality disorders.14 Among patients with BPD seen for treatment, 72 % have had at least 1 psychiatric hospitalization and 97 % have received outpatient treatment from a mean of 6.1 previous therapists.15, 16 Despite this high - use pattern, patients with BPD have high rates of treatment failur
Patients with BPD use more services
than those with major depression13 and other personality disorders.14 Among
patients with BPD seen for treatment, 72 % have had at least 1 psychiatric hospitalization and 97 % have received outpatient treatment from a mean of 6.1 previous therapists.15, 16 Despite this high - use pattern, patients with BPD have high rates of treatment failur
patients with BPD seen for treatment, 72 % have had at least 1 psychiatric hospitalization and 97 % have received outpatient treatment from a mean of 6.1 previous therapists.15, 16 Despite this high - use pattern,
patients with BPD have high rates of treatment failur
patients with BPD have high rates of treatment
failure.17, 18
«Staff splitting,» as mentioned earlier, is a much - discussed phenomenon in which professionals treating borderline
patients begin arguing and fighting about a
patient, the treatment plan, or the behavior of the other professionals with the
patient... arguments among staff members and differences in points of view, traditionally associated with staff splitting, are seen as
failures in synthesis and interpersonal process among the staff rather
than as a
patient's problem... Therapist disagreements over a
patient are treated as potentially equally valid poles of a dialectic.