Sentences with phrase «familial forms»

This «missing heritability» component has led to the conclusion that some forms of IBD — especially the familial forms — could be due to the profound effect of rare variants whose causes are yet to be discovered.

Presenilins 1 and 2 (PS1 and PS2) are the catalytic subunits of the γ - secretase complex, and genes encoding mutant PS1 and PS2 variants cause familial forms of Alzheimer's disease.

«Because we have shown that mutated forms of alpha - synuclein, which are associated with early onset familial forms of Parkinson's Disease, affect this process, we also now know that this is a function that may be impaired in people who carry these mutations.»

Because scientists have had difficulty analyzing these interactions, most research has focused on rare familial forms of the disease.

When compared to the enhanced alpha - synuclein production in the familial form of the disease, the modest effect created by the A to G mutation would be sufficient over a lifetime to increase the risk of PD, according to Soldner.

Ten percent of ALS patients suffer from a familial form of the disease, while FTD is caused in 40 % of patients by a genetic defect.

Not exact matches

Less obvious, but perhaps, arguable would be older and younger siblings where the older sibling has more perceived power, however it could take many forms, and might be argued that any close familial relationship is likely to develop a hierarchy of power, or pecking order, that invalidates any equal position in which to make a valid consent.

Part of the shocking revelation that Jesus brought us is that God doesn't just want us to go to a happy, peaceful place, but that he's inviting us to enter into a familial relationship with Him and as His children we will live with Him, do things with Him and and work with Him (and consequentially each other, forming a body that is One).

Folk culture stems from the people of a particular region and the familial and religious bonds that form the central threads of that region.

Somehow they tend to serve as «tribes,» forms of more - than - familial life that keep people from being overwhelmed by the blur of generalized religion yet challenge them to look at more than their own backyards and neighborhoods.

In fact, there may be such a word: C.S. Lewis in The Four Loves argues that on a level below genuine friendship — philia, which in Greek tradition is truly a form of love, just as much as eros (sexual love) or storge (familial affection)-- lies companionship.

Early onset or familial Alzheimer's, which can begin to manifest in a person's 30s, 40s, and 50s, is the less common form.

The symptoms of the familial and the sporadic forms of ALS are so similar, he added, that they probably share many common mechanisms.

Vallabh tested positive for the mutation that causes familial fatal insomnia (a form of prion disease) in 2011, soon after she and Minikel married.

Though a substantial portion of risk of this common disease is clearly familial, it has proven difficult to find genetic variants predisposing to its common forms.

An international research group has discovered that the mutated form of a gene called Palladin causes familial pancreatic cancer.

Finally, an inactivating mutation of LARP7 has been linked to a novel form of familial Primordial Dwarfism characterized by facial dysmorphism and intellectual disability (Alazami et al., 2012).

Advertising drama No amazes with not only its imaginative execution but its historical authenticity, fragile familial effort Sister is delicate, devastating and elegantly disarming, War Witch weaves astute portrayals into its ambitious African storyline, and the typically disorienting Like Someone in Love marks a return to form for Iranian auteur Abbas Kiarostami.

True to form, this beautifully made portrait of a teenage boy is exquisite in its embrace of neo-realism and true familial relationships in all their glory and complexities.

They are soon joined by blind boarder Will (John Malkovich) and, despite their drastically different lives, they begin to form an almost familial bond.

The director of the Cannes hits «Dogtooth» and «The Lobster» brings a new movie, «The Killing of a Sacred Deer,» with a plot described as «a surgeon forms a familial bond with a sinister teenage boy with disastrous results.»

«The Journey to Forming a Family» (4:34) gathers comments on the film's familial themes and why they are important to director / co-writer Lisa Cholodenko.

Like Lean on Pete, Arnold's film follows a rootless teenager in search of some form of familial belonging — in her case, with a gang of likewise aimless youths hawking magazine subscriptions across the midwest — but is supersized and expressively unruly where Haigh's is contained and watchful.

Not only was it an honor and privilege to be able to learn from Professor Lawrence - Lightfoot's ever - insightful commentaries on life phenomena, but the members of our seminar formed a learning community that was both rigorous and familial.

Love in many forms powers the book: familial, platonic and also romantic.

This is a story about connections and love in all forms — romantic, platonic, familial, obligatory, even of vocation.

Familial Shar - Pei Fever Chinese Shar - Pei dogs suffer from a strange form of arthritis.

A familial and heritable form has been identified in Maine Coons and Ragdolls and a genetic test is presently available in these breeds through the veterinary cardiac genetics lab at North Carolina State.

In humans only 3 genes have been identified, in some rare forms of familial idiopathic epilepsy.

Mutations in human PARK2 cause the most common form of familial Parkinson's disease, autosomal recessive juvenile parkinsonism, which has clinical and pathological similarities to canine multiple system degeneration.

In his newest creative works in oil paint, by means of once again observing carefully and realizing the intimate relations between family members, Zhang takes the complexity and concretization from the bloodline theme to form the main character's mutual and interweaving vision, as well as each family member's individual psychological projection and ego cognition that accompanies their familial role.

In this way, the digital montages work as an uncanny doubling of mother and daughter across multiple temporalities, highlighting their familial connection beyond material form.

«It not only expands the roster of artists working abstractly but also bravely tackles the quandary of black women artists who often have had to overcome familial uncertainty with their chosen careers, and have had to harness color, line, and form to address the inevitable and unavoidable political and personal challenges they have faced in the world.»

Her work weaves sonic and familial archives with landscape, technicolor, rhythm, form, and spirit.

Featuring: Amna Asghar, Dana Davenport, Umber Majeed, Tammy Nguyen, Ke Peng, Sahana Ramakrishnan, Sheida Soleimani Amna Asghar speaks on the construction and translation of disparate references, cultures, geographies, and generations from Pakistan and America; Dana Davenport addresses the complexity of interminority racism within her own community and institutions from her experiences as a Black Korean American; Umber Majeed's practice attempts to unpack the temporalities within South Asia as site, familial archival material, popular culture, and modern national state narratives; Tammy Nguyen interrogates natural sciences and non-human forms to explore racial intimacies and US military involvement in the Pacific Rim; Ke Peng documents the feeling of alienation and disorientation from urbanization and immigration by taking a journey into an imagined childhood in China, Hunan, where she was born and Shenzhen, a modern city where her family relocates to; Sahana Ramakrishan explores myths and religion from Buddhist and Hindu tales to speak upon the magic of childhood and the power dynamics of sexuality, race, and violence; Sheida Soleimani is an Iranian - American artist and a daughter of political refugees, making work to highlight her critical perspective on the historical and contemporary socio - political occurrences in Iran.

All around us we see relationships forming and breaking, familial bonds, obsessive social networking, and the compulsive building of alliances....

The book describes different familial patterns of parental alienation, compares alienation to a cult, explains how it is a form of emotional abuse, details the different catalysts to having the realization that one is an adult child of PAS, and describes the painful long - term consequences.

«Through the close friendships and familial relationships that form within the teams (of Holocaust survivors and Palm Beach County teens), the program is easing the isolation of some of the elderly survivors,» said Debbie Lipson, Ruth and Norman Rales Jewish Family Services Holocaust case manager.

Using EFT as a powerful vehicle for change, Annmarie works for transformation in all forms of human connection including individual, dyadic, familial, communal and faith relationships.

Some researchers have suggested that the familial continuity of certain forms of psychopathology is perhaps more distinct in girls than in boys.

The serendipitous approach to custody reflected in the District's presumption does not account for the real harm done to relationships when marriages or other familial unions dissolve, or when they never formed.

The authors propose that these results suggest that there are two forms of aggression in children and only aggression that has its basis in familial biology is associated with diminished serotonin function.

[74] I argue that this is a perceived issue because the imposition of non-Indigenous forms of governance has distorted our own understanding of familial and community relationships and responsibilities, and our ways of governing.

While sources of social influence outside of the familial circle begin to emerge in the form of peers and intimate partners [37], relationships with parents remain, for better or worse, socially relevant in the lives of individuals [10].

The profile form asks for information such as gender, race, and familial status and allows visitors to search by those criteria.