Sentences with phrase «fat cell models»

Researchers at the University of Memphis and University of Pennsylvania report the development of robust new liver and fat cell models that report circadian clock function.

Not exact matches

The researchers collected samples of indoor dust from 11 homes in North Carolina and tested extracts from the samples in a mouse pre-adipocyte cell model, 3T3 - L1 cells, often used to test compounds for potential effects on the accumulation of triglycerides, a type of fat.

Using human - derived glioblastoma cells in a mouse models, researchers found that the modified high - fat, low - carbohydrate diet increased life expectancy by 50 percent while also reducing tumor progression by a similar amount.

«We have identified a number of pharmaceutical compounds that selectively inhibit — in different experimental models — the mitochondrial enzyme responsible for the tumour growth, thus limiting fat synthesis and without harming normal cells.»

The researchers began with a mouse model that was genetically modified so that its fat cells could not create microRNAs.

«Natural killer cells help to drive inflammation, insulin resistance: Study in mouse models of diabetes identifies key immune mechanisms in abdominal fat.»

«Our next phase of research is to make these iPSCs into liver, muscle and fat cells, and then see if we can use them to model those tissues in people,» he says.

We have recently identified which cells are uniquely responsible for the metastasis formation in OSCC, and they exhibit the following characteristics: i) they are exclusive in their ability to generate metastases; ii) they express the fatty acid translocase CD36, and express a unique lipid metabolic signature; iii) they directly link metastasis predisposition to dietary fat content; iv) they increase their metastatic initiation potency when treated with palmitic acid; v) they are highly sensitive to CD36 inhibition, which almost completely abolishes their metastatic potential in preclinical models (Pascual et al., Nature 2016).

December 21, 2016 — Noteworthy NIH advances in basic research include an expanded map of the human brain, nanoparticles that convert white fat to calorie - burning brown fat, and a 3 - D cell culture model of the placenta.

But in the overflow model, the DNL would be enhanced because the cell is trying to rid itself of the excess glucose by producing extra fat.

Furthermore, CBD and another component of marijuana, tetrahydrocannabivarin (THCV), may reduce body weight, as animal models of obesity using overweight mice have shown THCV to increase metabolism of fat cells.