Sentences with phrase «fat than normal mice»

Scientists found that mice with a faulty internal Clock (right) gained more body fat than normal mice (left).

Mice with a disrupted biological clock slept less, ate more, and gained more body fat than normal mice, indicating that, when it comes to understanding the molecular basis of obesity, timing may be key.

On the other hand, as they aged, these «knockout mice» grew fatter than the normal mice, especially when fed a high - fat diet.

Not exact matches

Three groups of middle - aged mice (about a year old) were studied: one group ate a normal diet, in which fewer than 30 percent of calories came from fat, while two others were fed high - calorie diets in which 60 percent of the calories came from fat.

Moreover, mice engineered to generate smaller than normal quantities of SIRT1 carried relatively little fat in their blood, indicating that their cells hung onto it.

As a result, they have less than half of the fat tissue found in normal, aged mice.

When they exposed these mice to the cold, the animals developed far fewer beige fat cells than did normal animals, suggesting that macrophages were key to browning of white fat.

To investigate, Akhtar deleted the gene for Rac1 in female mice; their first litter of pups survived, but they were smaller than normal — probably because the milk they received contained less fat and protein than normal.

Fat mice fed huge quantities of it lived longer and aged more slowly than normal.

That research showed that mice on a normal diet who were exposed to low doses of antibiotics throughout life, similar to what occurs in commercial livestock, packed on 10 to 15 percent more fat than untreated mice and had a markedly altered metabolism in their liver.

And, consistent with other studies, when these mice ate a high - fat diet, they gained weight faster than their normal counterparts.

During this period, the mice on the high - fat diet gained 30 to 50 percent more body mass than mice fed a normal diet, and they developed more intestinal tumors than mice on a normal diet.

First, they found that the mice on a high - fat diet had many more intestinal stem cells than mice on a normal diet.

Some studies have identified a number of regions of methylated DNA (one key way in which epigenetic changes occur) that are different in fat cells of mice fed high - fat diets than in cells of mice with normal diets.

Over an eight - week period, a control group of mice fed a high - fat diet predictably became obese, but the mice whose Hedgehog pathway had been activated didn't gain any more weight than another control group fed on a normal diet.

The reason for this response, Gordon says, was twofold: Firmicutes bacteria transplanted from the fat mice produced more of the enzymes that helped the animals extract more energy from their food, and the bacteria also manipulated the genes of the normal mice in ways that triggered the storage of fat rather than its breakdown for energy.