Not exact matches
Defects in mitochondrial DNA lead to devastating genetic diseases, with such symptoms as brain abnormalities, severe fatigue, blindness or defective
heart function — and can be
fatal.
«Once we identify that disruption, we can begin exploring ways to restore normal gene function during early
heart formation — and reduce the number of babies born with debilitating, and sometimes
fatal, congenital
heart defects.»
At one end of the severity spectrum, early chronic valvular disease, some forms of hypertrophic cardiomyopathy and some mild congenital
heart defects may have little effect on an animal's lifestyle or life expectancy; at the other end, severe
heart failure can interfere with even simple activities and prove rapidly
fatal.
Joshua A. Stern, Washington State University, D09CA - 909 With his Pfizer Animal Health — MAF Fellowship, Joshua A. Stern, DVM, joins a team at Washington State University that may discover the genetic mutation that causes a
fatal, congenital
heart defect called subvalvular aortic stenosis in golden retrievers, one of America's most beloved breeds.