Not exact matches
To investigate, Walker Jackson of the Whitehead Institute in Boston, Massachusetts, and his colleagues created mice with a mutation associated with the
human prion
disease Fatal Familial Insomnia and injected some of their
brain tissue into the
brains of mice without the mutation.
Several
fatal neurological
diseases — including Creutzfeldt - Jakob
disease (CJD) in
humans and scrapie in sheep — are marked by the accumulation of protein deposits in the
brain.
For nearly 30 years, researchers have gathered evidence that a group of bizarre,
fatal brain diseases — including mad cow and its
human equivalent, Creutzfeldt - Jakob
disease — are caused not by a virus or bacterium but by an abnormal form of a protein, called a prion.
Researchers are reporting what they say is the most compelling evidence, to date, that the infectious proteins called prions that cause bovine spongiform encephalopathy (BSE), or «mad cow»
disease, have infected
humans, causing
fatal brain degeneration.
Prion
diseases are a group of rare,
fatal brain diseases that affect animals and
humans.