This study provides experimental evidence which shows the important role of RNA levels in the controlling
the fate of embryonic stem cells, and shows an understanding of RNA's ability to differentiate stem cells at the molecular level.
Not exact matches
Because the precise activation
of Hox genes is essential for a
cell's
fate, «the research should prove extremely useful in developing novel
embryonic stem cell - based therapies, Mazzoni adds.
In their experiments, about 20 percent
of embryonic stem cells lacking the microRNA exhibited expanded
fate potential.
«Finally, to assess the potential
fate of mtDNA under condition when the
cells can replicate extensively (longer than allowed by UK law), they derived human
embryonic stem cell (hESC) lines from five ePNT blastocysts.
Critical issues include: (i) heterogeneity in
stem cell populations (ii) regulation of cell fate choices; (iii) declining tissue performance with age and exposure to environmental injuries; (iv) the use of iPS and Embryonic Stem (ES) cells, and reprogramming methods for phenotyping disease states and potential use of these stem cells in the cli
stem cell populations (ii) regulation
of cell fate choices; (iii) declining tissue performance with age and exposure to environmental injuries; (iv) the use
of iPS and
Embryonic Stem (ES) cells, and reprogramming methods for phenotyping disease states and potential use of these stem cells in the cli
Stem (ES)
cells, and reprogramming methods for phenotyping disease states and potential use
of these
stem cells in the cli
stem cells in the clinic.
Lineage commitment in the mammalian embryo is most often depicted as a series
of binary choices between alternate
cell states, and increasing evidence supports the hypothesis that
fate decisions in
embryonic stem (ES)
cell cultures reflect these developmental processes [1].