Furthermore, it becomes increasingly evident that genome architecture varies significantly in individual cells and that many known
features of genome folding, such as partitioning of chromosomes into topologically - associating domains, represent a population average.
This will include a summary detailing the data that have been generated and key
features of the genome identified from genomic assembly and clone mapping / sequencing.
Not exact matches
A few that pop to mind are the Coconino Sandstone, the meandering / lateral channels in the Grand Canyon, the progressive order
of the fossil record (complete with a pre-hominid through hominid progression), forms which bear
features bridging the specially - created kinds (i.e. fish with tetrapod
features, reptiles with mammalian
features, reptiles with avian
features, etc), the presence
of anomalous morphological / genetic
features (e.g. the recurrent laryngeal nerve, male nip - ples, the presence
of a defunct gene for egg - yolk production in our own placental mammal
genomes), etc, etc..
Perhaps the most significant distinction between evolution and ID / creationism is evolution's ability to explain poor design
features, e.g. male nip - ples, the recurrent laryngeal nerve, the presence / location
of endogenous retroviruses, and (one
of my personal favorites) the presence
of a defunct gene for egg yolk protein in our placental mammal
genomes.
So as kids explore the interactive
features of the exhibit, like building their own dinosaur or exploring computerized
genome projects, they'll pick up some knowledge about DNA, species extinction and more.
Through detailed
genome comparisons, sequence - alignment algorithms and other bioinformatics tools run on Los Alamos computers, the Los Alamos team identified
features that differentiate among F. tularensis and other novel clinical and environmental Francisella isolates, providing a knowledge base for comparison
of new sequences from clinical or environmental surveys.
In Lausanne, the researchers carried out a detailed study
of the
genome and the «phenome» (the set
of all phenotypes or clinical
features)
of a family
of mice composed by 183 members.
Analysis
of the 1,042,519 — base pair Chlamydia trachomatis
genome revealed unexpected
features related to the complex biology
of chlamydiae.
Also online, an interactive
feature including informational graphics, video clips, and more, as well as accompanying Web resources, explore how plant
genome research is contributing to our understanding
of plant biology and evolution and leading to tangible benefits for society.
To identify signs
of a self - domestication process in humans, researchers made a list
of genes associated with domestication
features in humans, out
of the comparison with the
genome in Neanderthals and Denisovans, extinct human species.
They live inside their host's cells and have highly specialized
features: They are only able to reproduce inside the host's cells, they have the smallest known
genome of all organisms with a cell nucleus (eukaryotes) and they posses no mitochondria
of their own (the cell's power plant).
The observational study published in
Genome Biology utilized publicly available and unpublished data sets to find 2,147 vlincRNAs that cover 10 percent of the human genome, suggesting that their production is a common, yet undiscovered, feature of huma
Genome Biology utilized publicly available and unpublished data sets to find 2,147 vlincRNAs that cover 10 percent
of the human
genome, suggesting that their production is a common, yet undiscovered, feature of huma
genome, suggesting that their production is a common, yet undiscovered,
feature of human DNA.
Epiviz implements multiple visualization methods for location - based data (such as genomic regions
of interest) and
feature - based data (such as gene expression), using interactive data visualization techniques not available in web - based
genome browsers.
«A striking
feature of the phylogenetic tree based on S. aureus whole
genome sequencing was the presence
of multiple distinct clades,» said senior author Sharon Peacock from the University
of Cambridge and Wellcome Trust Sanger Institute.
A closer look at the transcriptome — all the parts
of the
genome that are actively expressed at a given time — confirmed that NFAT, when acting on its own, induces a second transcriptional program that has many
of the characteristic
features of CD8 T cell exhaustion.
Early comparative studies threw conserved regulatory regions, RNA genes, and other
features into relief, bringing meaning to much
of our
genome, including the 98 % that lies outside protein - coding regions.
«ID «ing
features of flu virus
genome may help target surveillance for pandemic flu: Findings may help health experts know which strains to watch.»
«It's essential to have all
of the great ape
genomes in order to understand the
features of our own
genome that make humans unique,» says Gregory Wray, an evolutionary biologist at Duke University in Durham, North Carolina, who was not involved in the study.
«It has long been speculated that hair
features could have been influenced by some form
of selection, such as natural or sexual selection, and we found statistical evidence in the
genome supporting that view,» added Dr Adhikari.
With colleagues, he used common
features in the
genomes of 36 modern mammals to sketch out the
genome of the creature from which they descended.
Using this method,
features of genomic organization including compartments, topologically associating domains (TADs) and chromatin loops were detected in single cells when averaged over the
genome.
Now, researchers writing in the Cell Press journal Cell Reports on February 12th have sequenced the complete
genome of one wild - caught individual, and they say that it has already told them more than they had anticipated about the butterflies and some
of their most intriguing
features.
Indeed, in an exhaustive search, they identified parallel
features in the
genomes of a more mysterious subterranean group
of archaea known as nanoarchaea.
While the octopus
genome resembles those
of other marine invertebrates in many respects, it also revealed unexpected
features that are key to understanding the origin and function
of its unique nervous system.
This snippet
of the human
genome, color coded for major
features, comes from a beach - towel - sized poster that represents all 2.9 billion bases.
A team
of scientists announced that they have sequenced the
genome of the common soil bacterium Streptomyces coelicolor — the largest microbial
genome to date — unearthing both promising and surprising genomic
features.
Zhao and colleagues examined the ability
of the CRISPR - Cas system, a set
of molecules borrowed from a form
of immune system in bacteria (CRISPR stands for clustered regularly interspaced short palindromic repeats, describing a
feature of this system in bacterial
genomes).
This «chromosomal disorder» is a key
feature of the gibbon
genome and has probably occurred after their secession from the ancestral line
of the apes and humans.
New work published in Proceedings
of the National Academy
of Sciences by lead authors Michael Raissig and Emily Abrash
features a collaboration born at Carnegie's Department
of Plant Biology between Bergmann and John Vogel (now at the Department
of Energy's Joint
Genome Institute) who met as postdocs at Carnegie.
From this we compared the genomic distributions
of our hotspots to the genomic distribution
of various
features associated with
genome evolution and genes that participate in particular biological processes.
The researchers uncovered a variety
of features in the cichlid
genome that enabled the fishes to thrive in new habitats and ecological niches within the Great Lakes
of East Africa.
After the sections
of DNA sequence have been assembled into a complete
genome sequence we need to identify where the genes and key
features are, but how do we do this?
«It shares the structure and many
features of the human
genome; many human proteins function just as well in fruit flies.
Another interesting
feature in their
genomes is the abundance
of transposable elements, «jumping genes» that can move to different parts
of the
genome to cause mutations or supply new elements to protein - coding genes.
Compared with the ancestral lineage, the East African cichlid
genomes possess: an excess
of gene duplications; alterations in regulatory, non-protein-coding elements in the
genome; accelerated evolution
of protein - coding elements, especially in genes for pigmentation; and other distinct
features that affect gene expression, such as insertions
of transposable elements and regulation by novel microRNAs.
Comparing humans and mice has the potential to reveal key
features of mammalian biology, and more insights will emerge as more
genomes are completed.
Henk Stunnenberg, leader
of one
of the research groups that carried out the study and coordinator
of both Heroic and the recently started High Impact Project BLUEPRINT, said: «The epigenetic make - up - a layer
of regulatory instructions on top
of the
genome -
of the pure embryonic stem cells shows remarkable and unexpected
features, in particular with respect to developmental genes.
Genome mining
of Streptomyces scabrisporus NF3 reveals symbiotic
features including genes related to plant interactions.
Additional
genome features include an abundance
of tandemly repeated transfer - RNA - containing arrays, which may have a structural function in the
genome.
Thus, we've established the toolbox
of a
genome sequence and a methodology to transform Sciara, so the time is now ripe for the scientific community to study all the unique
features of Sciara.
One aim
of the sequencing project was to learn from the
genome's current
features how bread wheat has evolved since its domestication.
Another distinctive genetic
feature of mucosal melanoma is its high rate
of copy number and structural variants, demonstrated both by array - based comparative genomic hybridization and whole -
genome sequencing.
In addition to finding vaccine candidates, «the most striking
feature of N. meningitidis from a
genome perspective is that there are more contingency genes than any other bacterium or organism studied so far,» says Hervé Tettelin, leader
of the N. meningitidis sequencing project at TIGR.
To mark this historic accomplishment, the National Human
Genome Research Institute (NHGRI) and the Department
of Energy (DOE) are holding a landmark scientific symposium on April 14 - 15 that will
feature some
of the biggest names in genetics
of the past 50 years including: James Watson, Francis Collins, Marshall Nirenberg and Stanley Cohen.
Taxonomically - restricted genes, especially those that seem to have arisen de novo from non-coding sequence [50]--[55], are likely more crucial to organismal fitness than previously recognized [56], and it is becoming clear that these genes may be a common
feature of many
genomes [38], [57], [58].
The short generation time and relatively compact
genome of Arabidopsis make it an ideal model system for understanding numerous
features of plant biology, including ones that are
of great pharmaceutical or agricultural value.
When turned on, this
feature of the Unlocking Life's Code website will highlight words on the page that are found in the National Human
Genome Research Institute's Talking Glossary
of Genetic Terms.
The archive sites will allow researchers to access data from old releases via our web - based tools, and additionally will be able to display track hubs containing alignments and
features located on older versions
of genome assemblies that have since been upgraded in the live site.
The designer
features of Sc2.0 plus the international consortium
of research scientists now working together to build the Sc2.0
genome will be described.
Perhaps the most striking
feature is the extent to which individual genes and entire blocks
of chromosomal regions have been duplicated in the Arabidopsis
genome.