Panel (a) shows the PCoA of coprolites and
the fecal microbiota from extant indigenous cultures plotting PC1 vs. PC2.
To define a relationship between gut bacteria and the efficacy of ACT, the researchers transplanted
fecal microbiota from Jackson mice to Harlan mice.
The goal of the study was to explore whether
fecal microbiota from human IBS patients with diarrhea has the ability to influence gut and brain function in recipient mice.
We transplanted
fecal microbiota from adult female twin pairs discordant for obesity into germ - free mice fed low - fat mouse chow, as well as diets representing different levels of saturated fat and fruit and vegetable consumption typical of the U.S. diet.
Separate groups of germfree mice were colonized with uncultured
fecal microbiota from each member of four twin pairs discordant for obesity or with culture collections from an obese (Ob) or lean (Ln) co-twin.
Ridaura et al. (1241214; see the Perspective by Walker and Parkhill) obtained uncultured
fecal microbiota from twin pairs discordant for body mass and transplanted them into adult germ - free mice.
Not exact matches
After transferring
fecal matter
from one group of rodents to another, they observed similar changes in the gut
microbiota, acetate levels, and insulin.
Prof. Severine Vermeire (KU Leuven / UZ Leuven): «In the future, gut bacteria may be used to help identify PSC patients with a more or less aggressive disease, or patients that may benefit
from microbiota - based therapies, such as
fecal microbiota transplantation or targeted pre - and probiotics.»
«So far, it has not been sufficiently tested whether and how successful
fecal transplantation is for the permanent settlement of
microbiota from a healthy donor to a patient,» said Alexander Loy of the Department of Microbiology and Ecosystem Research, University of Vienna.
In the first study, scientists transplanted
fecal material
from exercised and sedentary mice into the colons of sedentary germ - free mice, which had been raised in a sterile facility and had no
microbiota of their own.
Using
fecal transplants, researchers transferred
microbiota from IBS patients with or without anxiety into germ - free mice.
Young and colleagues used DNA sequencing to study the composition and structure of
fecal microbiota (bacteria) in stool samples
from 14 patients before and two to four weeks after
fecal transplant.
Fecal microbiota transplant
from a rational stool donor improves hepatic encephalopathy: a randomized clinical trial.
Two new gene clusters involved in the degradation of plant cell wall
from the
fecal microbiota of Tunisian dromedary
Two new gene clusters involved in the degradation of plant cell wall
from the
fecal microbiota of Tunisian dromedary — Rihab Ameri — PLoS One
For example, 2013 saw studies showing that transplanting human
fecal microbiota into mice could induce obesity and its associated metabolic phenotypes, and human data
from a controlled study suggesting the procedure could treat recurrent C. difficileinfection.
Correspondence:
Fecal Microbiota Transplant
from a Rational Stool Donor Improves Hepatic Encephalopathy: A Randomized Clinical Trial — Benjamin H Mullish — Hepatology
Then you will learn more about it at the Corner
from OpenBiome, a non-profit organization that helps collect stool samples
from healthy donors to support physicians in
fecal microbiota transplants.