For example, 2013 saw studies showing that transplanting human
fecal microbiota into mice could induce obesity and its associated metabolic phenotypes, and human data from a controlled study suggesting the procedure could treat recurrent C. difficileinfection.
Not exact matches
In the first study, scientists transplanted
fecal material from exercised and sedentary mice
into the colons of sedentary germ - free mice, which had been raised in a sterile facility and had no
microbiota of their own.
Ridaura et al. (1241214; see the Perspective by Walker and Parkhill) obtained uncultured
fecal microbiota from twin pairs discordant for body mass and transplanted them
into adult germ - free mice.
We transplanted
fecal microbiota from adult female twin pairs discordant for obesity
into germ - free mice fed low - fat mouse chow, as well as diets representing different levels of saturated fat and fruit and vegetable consumption typical of the U.S. diet.
Using
fecal transplants, researchers transferred
microbiota from IBS patients with or without anxiety
into germ - free mice.
Scientists are excited by recent success with
fecal microbiota transplants (FMT), transfer of healthy
fecal matter
into ailing patients, notably those with clostridium difficile (C. diff), a bacterial infection acquired after antibiotics, often in hospitals, that kills more than 15,000 people a year.