Sentences with phrase «female lymphocytes»
They found that about 3 to 5 percent of female lymphocytes expressed two copies of these genes, as well as two copies of a gene unrelated to immunity.
https://www.sciencedaily.com/
Because Xist in the female lymphocytes was present but simply wasn't localizing to the proper place on the inactive X, the research team took a closer look at two proteins, YY1 and hnRNPU, that are known to bind with Xist and possibly play a role in moving it back to the inactive X after lymphocytes are stimulated.
Not exact matches
To address this question, the Penn researchers examined lymphocytes donated by healthy human females as well as «naïve,» or unstimulated T and B cells from female mice.
The findings that even healthy females had such unusual maintenance of the inactive X in their lymphocytes was entirely unexpected.
«So it was really shocking to us that lymphocytes in normal females lacked these markers of X inactivation as well.»
The elevated incidence of glomerulonephritis in p21 - deficient mice, with increased severity among females, has been reported previously (35) and is attributable to an autoimmune process produced by abnormal proliferation of memory T - cell lymphocytes.