In other labs, some intriguing differences between male and
female mice test subjects have already begun to emerge.
Not exact matches
Fertility
tests of the
mice in adulthood showed that those whose mothers had been fed a high - fat diet while breastfeeding had decreased litter size, longer duration from mating to date of birth and impaired pregnancy rate in both
female and male
mice.
To
test a nonpermanent approach, the team gave normal
female mice the MIS protein as a twice - daily shot.
To
test whether such effects could be transmitted to the next generation, Nestler took another group of bullied
mice and bred them with
females, but kept them from ever meeting their offspring.
Further, two
female offspring from each of these litters were mated with unexposed male
mice and
tested for maternal behavior using the same assays used to
test their mothers.
Both male and
female mice whose mPOA neurotensin neurons were artificially driven this way showed a preference in standard
tests for moving closer to
mice of the opposite sex.
To
test whether these changes could lead to pre-term birth, the researchers carefully monitored
females whose amniotic sacs had been injected with MVs at day 14.5 of pregnancy (a full - term
mouse pregnancy lasts 19 days).
Fertility
tests of the
mice in adulthood showed that those whose mothers had been fed a high - fat diet while breastfeeding had decreased litter size, longer duration from mating to date of birth and impaired pregnancy rate in both
female and male
mice.
To
test whether sex hormones could account for these differences, the researchers removed the ovaries from
female mice and the testes from male
mice.
The researchers purified 312 of the proteins, injected them individually into
female mice, waited for the
mice to develop antibodies against the proteins, and then
tested the offspring of the injected
mice for their susceptibility to the bugs.
We
tested this hypothesis with 3 — 6 - month - old male and
female wild - type
mice.
The present study was aimed at identifying behavioral
tests that are most sensitive to the emergence of behavioral / neurological deficits in male and
female SOD1 G93A
mice (SOD - 1) compared to wild - type (WT) controls.
In the study, researchers removed the ovaries of
female mice to mimic the effects of post-menopausal women before implanting estrogen - receptor positive cancer tumors into the
test subjects.
Using a male Micro-USB to
female USB adapter we
tested the
mouse and keyboard support.