Embryo -
fetal development studies carried out on mice and rats also observed a reduced number of pups per litter, reduced pup weight at birth, and an increased frequency of skeletal «variations» in pups after pregnant females were given high doses of DEP.
Not exact matches
Male - type tendencies (vigorous play, sexual arousal by females, and physical aggressiveness) followed the testosterone - rich intrauterine
fetal development of the people he
studied, regardless of efforts to socialize them as females after birth.
CONCLUSIONS: Our
study suggests that high folate intake may have adverse effects on
fetal mouse
development and that maternal MTHFR deficiency may improve or rescue some of the adverse outcomes.
A. Lucas et al., «A randomised multicentre
study of human milk versus formula and later
development in preterm infants,» Arch Dis Child
Fetal Neonatal Ed (England) 70, no. 2 (Mar 1994): F141 — 6.
Introduction The emerging view of epidemiological
studies indicates the importance of the intrauterine environment in early
fetal development.
«During
development, both male and female embryos start out having certain
fetal tissue called the Müllerian duct mesenchyme,» said Jose Teixeira, professor of reproductive biology in the College of Human Medicine and lead author of the federally funded
study.
Skinner was
studying how a commonly used agricultural fungicide, when introduced to pregnant mother rats, affected the
development of the testes of
fetal rats.
The enzyme at the center of this
study, ADAR1, is normally expressed during
fetal development to help blood cells form.
At the University of Southern California, researchers have isolated the two proteins in the Zika virus that seem to be the culprits «that block normal
fetal brain
development,» says Jae Jung, the
study's lead author and a microbiologist at USC's Keck School of Medicine.
A 2010
study in Stem Cells and
Development showed that
fetal cells can migrate to the brain of a mother mouse and mature into neurons, Nelson says.
Several
studies had already pinned some of the visible abnormalities in clones on the absence of vital molecules that turn gene expression on and off during
fetal development.
The
study analysed the effects of SSRI use during pregnancy on the course of pregnancy,
fetal development and birth outcomes.
«This
study shows that the combination of physical and psychosocial stressors during
fetal development magnifies the effect of each exposure,» says lead author Frederica Perera, DrPH, PhD, director of the Center.
«Research using human
fetal tissue is invaluable to scientific and medical communities worldwide that
study and work on human
development and disease,» said Hans Clevers, president of the International Society for Stem Cell Research (ISSCR), and a stem cell researcher at Utrecht University in the Netherlands, in a statement released 14 July.
«This is the kind of
study where you think «Yes, I can believe these results,»» because they fit well with what scientists know about
fetal brain
development, says cognitive scientist Karin Stromswold of Rutgers University, New Brunswick, in New Jersey.
In a separate
study, mice were exposed to TF only during
fetal development and as newborns.
Fat soluble vitamins have distinct roles in
fetal growth and
development and this
study's objective was to determine the effects of a high fat soluble vitamin diet during pregnancy on body weight gain, food intake and preference for palatable solutions in male Wistar rat offspring.
Neuroscientists have
studied the shuttling of neurons between the eyes and brain of
fetal cats to shed light on visual
development in mammals.
The
study is the first to link asthma to hexachlorobenzene exposure during
fetal development, and builds on two earlier
studies that linked the respiratory disease to polychlorinated biphenyls.
Interestingly, women with lupus display autoantibodies and cytokines, which — when
studied in animals — have been shown to alter
fetal brain
development and induce behavioural irregularities in offspring.
«The most important message is that if you take the occasional paracetamol, it's not going to do your baby any harm,» says Richard Sharpe of the University of Edinburgh, UK, who was not involved in the
study but who investigates the causes and origins of
fetal sexual
development in boys.
«Normal maternal thyroid hormone levels are essential for normal
fetal growth and brain
development, so our findings could have significant public health implications,» said Jonathan Chevrier, a University of California, Berkeley epidemiologist and lead author of the
study, which was published in the journal Environmental Health Perspectives.
This finding adds to previous
studies that have linked acceptable air pollution levels with other complications including cognitive decline and
fetal growth
development.
One of the largest
studies carried out to date in order to determine mercury levels in umbilical cord blood samples and its association with different reproductive effects: measurements of
fetal development (weight, height and head circumference at birth), placental weight, duration of pregnancy and risk of premature birth.
The use of aborted
fetal tissue has sparked controversy in the U.S., but many scientists say it is essential for
studies of HIV,
development and more
This unique, prospective
study design allowed Peterson and his colleagues to follow babies from a critical point in
fetal brain
development in utero, through birth, and all the way into toddlerhood.
The insight «builds nicely on a number of
studies» showing that parts of the
fetal immune system are in place fairly early in
development, says Jakob Michaelsson, an immunologist at the Karolinska Institute in Stockholm.
The new cellular and molecular data uncovered in the current
study will be «exploited in the future to further improve liver bud organoids» and «precisely recapitulate differentiation of all cell types» in
fetal human
development, the authors write.
Martin Raff, Max Cooper, and J.J. Owen show that cells capable of producing antibodies are generated in the
fetal liver of mice, demonstrating that the mouse
fetal liver represents a mammalian equivalent to the avian bursa and providing an accessible in vitro system to
study B cell
development in the mouse.
Though Diamond's lab has received federal funding, he said researchers who have been cut out include those who
study pregnancy,
fetal development or neural stem cells.
ONE - PARENT SAMPLE SET PARENTAL GUIDANCE RULES: Maternally methylated (red dots) and paternally methylated (blue dots) regions across the human autosomal chromosomes, based on
studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal -
Fetal Biology, National Research Institute for Child Health and
Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expressed.
In particular, the lab
studies the non-canonical Wnt signaling pathway, which comprises a family of proteins with great implications in
fetal development as well as cancer.
For example, one 2008
study found that just two cups of coffee ingested during pregnancy may be enough to affect
fetal heart
development and reduce heart function over the entire lifespan of the child.
A
study by the Environmental Working Group found a total of 167 chemicals (the average was 91) in the blood and urine of the
study's participants, including 76 carcinogens, 94 chemicals known to be toxic to the brain and nervous system, and 79 that can cause birth defects or abnormal
fetal development.
Whether the hormones in birth control pills could affect
fetal development when used around the time of conception hasn't been well -
studied, the
study authors explained in background notes.
«This
study indicates that chocolate could have a positive impact on placenta and
fetal growth and
development and that chocolate's effects are not solely and directly due to flavanol content,» says Emmanuel Bujold, M.D., one of the researchers on the
study.
Results from an observational pilot
study from Italy21 indicate mild to moderate ID during
fetal life affects cognitive
development, especially verbal abilities, even in absence of maternal thyroid insufficiency.