Not exact matches
«In a single mouse, for example, maybe 100
cells will be
infected, which is very
few compared with other viruses such as the flu.»
«The best explanation for what we are seeing is that frequently, after exposure to HIV, a
few cells in the genital tract are
infected, without establishment of a systemic infection,» says senior investigator Eric Hunter, PhD, professor of pathology and laboratory medicine at Emory University School of Medicine, Emory Vaccine Center, and Yerkes National Primate Research Center.
When it reaches the brain, Zika virus
infects neuronal stem
cells, which will generate
fewer neurons, and by inducing chronic stress in the endoplasmic reticulum, it promotes apoptosis, i.e. the early death of these neuronal
cells.
«One has to collect a lot of
cells to measure the latent reservoir,» Richman says, noting that
fewer than one
cell in a million is latently
infected.
People
infected with HIV have
few signs of microbial translocation during the first six months of infection as it takes time for the virus to kill off epithelial
cells and weaken the gut wall so that bacteria can leak through — so treating them early could be more effective.
A Zika -
infected organoid (right) shows collapse of the rosette, with
fewer neural stem
cells and neurons.
To create the maps, Spruston and HHMI neuroscientist Jayaram Chandrashekar injected mouse brains with viruses that
infect only a
few cells at a time, prompting them to produce fluorescent proteins.
Until this week, the WHO recommended that HIV treatment should begin when each millilitre of an
infected person's blood contains
fewer than 350 CD4
cells, the white blood
cells targeted and destroyed by HIV.
Currently, the WHO recommends that HIV treatment should not begin for most
infected people until each cubic millimetre of their blood contains
fewer than 350 CD4
cells, the white blood
cells targeted and destroyed by HIV.
As a result,
fewer infected red blood
cells might clog up the tiny blood vessels in patients» organs.
The experiment's final product is equivalent to the naturally occurring genetic code of M. genitalium, with two minor exceptions: The scientists disabled the gene that gave the bug power to
infect human
cells, and they added a
few «watermarks,» short strips of signature genetic code that identify the product as man - made.
A) Lung section: arrows are pointing at
few infected cells (red - purple).