Not exact matches
This is
interesting, because the hippocampus is known to be critical for learning and memory, and is widely thought to be one
of the
few parts
of the brain that continues to produce new
cells throughout life.
To cite a
few instances, polymerase chain reaction (PCR), a molecular method developed over three decades ago, has been widely applied in disease diagnosis, disease mechanism deciphering, and prognosis prediction; the elucidation
of tyrosine kinase activity in cancer
cells has led to the development
of novel drugs for cancer treatment; and the identification
of proteins and genetic molecules by molecular methods as biomarkers for disease diagnosis and prognosis has been drawing great
interest.
However, with
few exceptions, the stem
cell and regenerative medicine industry has remained inadequately capitalized to carry out large - scale clinical trials independently, and major pharmaceutical firms have tended to show more
interest in the use
of hiPSCs as a source
of large, pure populations
of specific somatic
cells for use in drug compound screening and toxicology tests, than they have in therapeutic uses
of stem
cells and their derivatives.
However some technical challenges still need to be taken to make the technology more accessible and usable to its full potential: gaining selective and comprehensive genetic access to the neurons
of interest, controlling variation in the expression
of the optogenetic tools (when using viruses) and its precise localization (axon vs. presynaptic terminals), tailoring light - delivery system signals to individual
cells in a population rather than the population as a whole, developing observation techniques which have the same spatial and temporal resolution as those tools... to cite only a
few of them.
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