Sentences with phrase «fibrils bind»

Not exact matches

Small molecules binding to amyloid fibrils.

In addition to uncovering compounds with therapeutic potential for Alzheimer's disease, this research presents a new approach for identifying proteins that bind to amyloid fibrils — an approach that could have broad applications for treating many diseases.

The final β - sheets bind together and stack up to form the damaging fibrils.

The amyloid - beta bound itself to C. albicans and grew fibrils that entombed the fungal invader — and as part of that process, created plaques of amyloid - beta.

Four of the mAbs, 2T5C9, 2G9C, T1F11, and TB2H7, demonstrated diagnostic potential in enzyme - linked immunosorbent assays (ELISA) by their low to sub-nanomolar cross-reactivity with recombinant wild - type (WT) and mutant TTR aggregates and lack of binding to native TTR or amyloid fibrils formed by other peptides or proteins.