In Alzheimer's disease proteins clump together to long
fibrils causing the death of nerve cells.
Not exact matches
Co-lead researcher, Australian National University Professor John Carver, said that two unrelated proteins aggregate in UHT milk over a period of months to form clusters called amyloid
fibrils, which
cause the milk to transform from a liquid into a gel.
«Large aggregates of ALS -
causing protein might actually help brain cells: UNC School of Medicine scientists add to evidence that small aggregates of SOD1 protein are the brain - cell killing culprits in ALS, but the formation of larger, more visible, and
fibril - like aggregates of the same protein may protect brain cells.»
Researchers have hypothesized that these
fibrils are what kill neurons and
cause ALS in some people.
For example, clumps of proteins called amyloid
fibrils are thought to be the
cause of Alzheimer's disease as well as several other devastating illnesses.
If the newly discovered beta - sheet structure idea could be integrated as building blocks into such artificially designed proteins, it would improve their ability to attach to the disease -
causing fibrils — a first step in the development of new agents against Alzheimer's and other neurodegenerative diseases.
«Amyloid
fibrils are normally only found in diseases
caused by protein misfolding, such as Alzheimer's or Parkinson's disease, so the natural presence of multiple amyloids in the semen of healthy men was completely unexpected,» said Warner C. Greene, MD, PhD, senior investigator and director of the Gladstone Institute of Virology and Immunology.