When the BBB is disrupted,
fibrinogen leaks into the brain and forms deposits that activate microglia, the brain's immune cells.
Not exact matches
She previously showed that when blood
leaks into the brain,
fibrinogen causes inflammation by acting in brain immune cells, which can lead to brain damage.
They found that when
fibrinogen (a blood - clotting protein)
leaks into the central nervous system, it stops brain cells from producing myelin and, as a result, prevents repair.