Sentences with phrase «fibrinogen stops»
«We found that fibrinogen stops adult stem cells from transforming into the mature cells that produce myelin,» explained first author of the study Mark Petersen, MD, a visiting scientist in Akassoglou's laboratory and an assistant adjunct professor of pediatrics at UCSF.
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Balanced amounts of fibrinogen, thrombin and fibrin are a key part of the body's health and its ability to close off wounds and stop loss of blood.
They found that when fibrinogen (a blood - clotting protein) leaks into the central nervous system, it stops brain cells from producing myelin and, as a result, prevents repair.
Her aim is to understand, at the molecular level, the mechanisms that control communication between the brain, immune system, and blood vessels — with the ultimate goal of designing new therapies that slow, stop, or reverse the progression of a wide range of neurological disorders, such as MS. Recently, Dr. Akassoglou's lab identified how microglia — a type of immune cell that acts as the brain's first line of defense — are activated when fibrinogen enters the brain or spinal cord.