Sentences with phrase «fibroblast cells shows»

This microscopic image of fibroblast cells shows the induction of cell fusion by a newly described gene and its protein, called myomerger.

Not exact matches

Ueli Schibler of the University of Geneva showed in 1998 that the per genes of rat connective - tissue cells called fibroblasts are active according to a circadian cycle.

Two months after therapy, tissue analysis showed less scarring and higher levels of regenerative agents such as fibroblast growth factor — which accelerate healing — in rats treated with SIS plus stem cells compared with those treated with SIS alone.

Hayashi then drew on other research showing that one key regulatory molecule (activin A) and a growth factor (basic fibroblast growth factor) could convert cultured early embryonic stem cells into cells akin to epiblasts.

A study by Mo's group in a 2011 issue of Experimental Biology and Medicine (236:604 - 613) showed that normal fibroblasts are 10-fold more resistant than murine B16 melanoma cells to geranylgeraniol - mediated growth suppression.

«We also showed for the first time that AHR signaling in primary human orbital fibroblasts disrupts the pro-fibrotic Wnt / β - catenin pathway, which is important for scar cell formation,» noted Dr. Phipps.

The experiments, including studies conducted in a bioengineered 3 - D model of lung tissue seeded with relevant cells, showed that CHI3L1 regulates a pathway that recruits cells such as macrophages and fibroblasts that produce the scarring, or fibrosis.

Earlier laboratory studies had shown that fetal fibroblasts, closely related cells from the fetus, respond to tamoxifen by producing a natural peptide called transforming growth factor beta - 1 (TGF beta - 1).

In fact, about a year ago, Jerry Shay and his colleagues at the University of Texas Southwestern Medical Center in Dallas showed that adding the enzyme to normal connective tissue cells called fibroblasts extends their life - span (ScienceNOW, 13 January 1998).

The experiment shows that β1 - integrin — one of 28 types of integrin — maintains a link between the stem cell and its environment, and interacts biochemically with a growth factor called fibroblast growth factor [FGF] to promote stem cell growth and restoration after muscle tissue injury.

(D) Transmission electron micrograph showing UCP - immunogold (10 nm, indicated by arrows) in a mitochondrion of an interstitial fibroblast - like cell of the rope tissue.

(B) Transmission electron micrograph showing an interstitial fibroblast - like cell packed with mitochondria (arrow) with dense cristae and small lipid droplets in the rope tissue.

They have already shown that they can transform human fibroblast cells into pluripotent stem cells, and now plan to start working on delivering the proteins needed to differentiate stem cells into specialized tissues.

It has also been shown that fibroblasts [43], [60] and placenta - derived progenitor cells [43] are unable to maintain visual functions long - term, further indicating that the rescue effects seen in the RCS rat model are not the result of a non-specific event.

In the current issue of the journal Developmental Cell, the scientists show that the secret to this switch lies in the cells that surround the muscle cells, known as fibroblasts, which send signals that tell cardiomyocytes to divide or get bigger in size.

«We've always suspected that different cell types are involved in determining how a heart is built,» said GICD Director and senior author Deepak Srivastava, MD. «Our research showed that the signals from cardiac fibroblasts contribute to the different responses of cardiomyocytes.»

In these studies we have shown that losartan treatment targets specific cells within the sclera called fibroblasts.

Here the authors, using an ex-vivo model, show that cancer - associated fibroblasts facilitate colon cancer cells invasion in a matrix metalloproteinase - independent manner, likely by pulling and stretching the basement membrane to form gaps.

Here we show that an abundant stromal cell population, cancer - associated fibroblasts (CAFs), promote cancer cell invasion through the BM.

Here we show that senescent human fibroblasts display molecular markers characteristic of cells bearing DNA double - strand breaks.