Sentences with phrase «fibroblast growth»

The list includes platelet - derived growth factors (PDGF), ß - thromboglobulin, fibroblast growth factor, insulin - like growth factor 1, epidermal growth factor, and vascular endothelial growth factor.

It is strongly associated with a recently acquired retrogene encoding fibroblast growth factor 4 (fgf4)(Parker et al. 2009).

Dietary phosphorus is readily absorbed in the small intestine, and in healthy individuals, excess phosphorus is excreted by the kidneys under the regulatory action of the endocrine hormones: parathyroid hormone (PTH), vitamin D, and fibroblast growth factor - 23 (FGF - 23).

Finally, acute changes in blood calcium concentrations do not seem to elicit the secretion of the phosphaturic hormone fibroblast growth factor 23 (FGF - 23), which is produced by bone - forming cells (osteoblasts / osteocytes) in response to increases in phosphorus intake (see the article on Phosphorus)(2).

Some of the key players in this hormonal symphony are hepatocyte growth factor and fibroblast growth factor.

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet - induced obese mice.

At the same time, the protein Vascular Endothelial Growth Factor (VEGF) stimulates blood supply for the damaged tissue, Fibroblast Growth Factor - 2 (FGF - 2) stimulates the damaged cells to grow and reproduce themselves, Transforming Growth Factor - beta (TGF - beta) stimulates cartilage to grow, and Stem Cell Factor (SCF) stimulates your native inactive stem cells to become activated and assist in the repair of the damaged tissue.

A very neat paper shows that transgenic mice made to overexpress a certain hormone live much longer than wild type mice: The starvation hormone, fibroblast growth factor - 21, extends lifespan in mice.

First of all, I'll just emphasize something from the title of the paper, namely that fibroblast growth factor, or FGF - 21, is the starvation hormone.

• Insulin - like Growth Factor 1 (IGF - 1) • Fibroblast Growth Factor (FGF) • Transforming Growth Factor — Beta Superfamily (TGF - beta)

Fibroblast growth factors activate mitogen - activated protein kinase pathways to promote migration in ovine trophoblast cells

Results: Fibroblast growth factor 2 (FGF2) treatment reduced expression of β - cell markers, (INS, MAFB, SLC2A2, SLC30A8, and GCK) and activated ectopic expression of MYC, HES1, SOX9, and NEUROG3.

hESC lines I6 and H9 were maintained on Matrigel (BD Biosciences, Bedford, MA; http://www.bdbiosciences.com) coated dishes in medium (comprised of Dulbecco's Modified Eagle's Medium / Ham's F12 supplemented with 20 % knockout serum replacement (KSR), 2 mM non-essential amino acids, 4 mM L - glutamine, 0.1 mM β - mercaptoethanol, 50 µg / ml Penn - Strep, and 4 ng / ml of basic fibroblast growth factor) conditioned with mouse embryonic fibroblasts for 24 hours as previously described [9], [10].

The tiny fish can regrow fins and even repair damaged heart tissue with genes called fibroblast growth factors and neuregulin 1, respectively.

Differentiation took place either in control culture media, or in the presence of various agents including retinoic acid (RA), Fibroblast Growth Factor - 2 (FGF2) and Wnt pathway activators.

Cells were cultured on irradiated mouse embryonic fibroblasts (MEF) in DMEM / F12 culture medium supplemented with KnockOut serum replacer (20 %), non-essential amino acids (0.1 mM), L - glutamine (1 mM), ß - mercaptoethanol (0.1 mM) and 100 ng / ml zebrafish basic fibroblast growth factor.

Human fetal NSCs (ReNCell VM, Chemicon) were cultured on laminin - coated dishes in ReNcell maintenance medium (Chemicon) in the presence of basic fibroblast growth factor 2 (bFGF2), following the manufacturer's instructions.

Fibroblast growth factor - 2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS.

Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor - binding protein in neurons.

The conventional hESC medium contained 80 % (vol / vol) KnockOut Dulbecco's Modified Eagle's Medium (DMEM) and 20 % (vol / vol) KnockOut serum replacement supplemented with 2 mM Glutamax, 0.1 mM β - mercaptoethanol, 0.1 mM MEM non-essential amino acids (Cambrex Bio Science, Walkersville, Inc., Walkersville, MD), 50 U / ml penicillin - 50 μg / ml streptomycin (Cambrex Bio Science) and 8 ng / ml recombinant human fibroblast growth factor (bFGF, R&D Systems, Minneapolis, MN).

In hESCs, Fibroblast growth factor (FGF), activin, and Bone morphogenetic signaling (BMP) signaling have been shown to be critical in maintaining self - renewal [19].

and cultured in 5 % O2 / 7 % CO2 in Bottenstein - Sato F12 medium with 10 ng / ml human recombinant basic fibroblast growth factor (Peprotech) on a substrate of 1 µg / cm2 fibronectin (Chemicon) and 0.5 µg / cm2 laminin (Invitrogen).

The latest study builds on earlier research from Izpisúa Belmonte's laboratory showing that extra limbs could be induced to grow in embryonic chicks by implanting beads soaked in fibroblast growth factor (FGF).

Maintenance of Multipotency in Human Dermal Fibroblasts Treated with Xenopus laevis Egg Extract Requires Exogenous Fibroblast Growth Factor - 2.

Shuizi Yu (Brand, TUD)-- «Biophysical characterization of fibroblast growth factor 8 signalling and morphogen gradient formation in vivo» (2010)

The use of basic fibroblast growth factor (bFGF) for enhancement of bone ingrowth into pyrolized bovine bone.

Autocrine fibroblast growth factor 2 increases the multipotentiality of human adipose - derived mesenchymal stem cells.

The overexpression of basic fibroblast growth factor boosts bone fracture healing capacity of mesenchymal stem cells via the secretion of paracrine - acting factors

Elevated fibroblast growth factor 23 (FGF - 23) is associated with increased risk of recurrent major cardiovascular (CV) events in patients after an acute coronary syndrome (ACS), according to a study published online April 18 in JAMA Cardiology.

Basic fibroblast growth factor reduces scar by inhibiting the differentiation of epidermal stem cells to myofibroblasts via the Notch1 / Jagged1 pathway.

The Gut Microbiota Regulates Endocrine Vitamin D Metabolism through Fibroblast Growth Factor 23 — Stephanie A. Bora — Frontiers in Immunology

The most common fusion they observed involved the genes FGFR (fibroblast growth factor receptor) and TACC (transforming acidic coiled - coil).

The Gut Microbiota Regulates Endocrine Vitamin D Metabolism through Fibroblast Growth Factor 23

[4] Of note, anosmin may enhance fibroblast growth factor signaling through the fibroblast growth factor receptor 1.

The research team, spearheaded by postdoctoral fellow Yajie Liang, Ph.D., wondered whether the cells» survival could also be enhanced with steady doses of a compound called basic fibroblast growth factor (bFGF), an «energy drink» that spurs cells to grow.

Metastatic variant of MCF7 (MCF7 - BoM2d cells) was suspended in DMEM - F12 medium supplemented with 2 % of B27 supplement, 0.4 % BSA, 4 μg / mL insulin, 20 ng / mL basic fibroblast growth factor (bFGF), and 20 ng / mL EGF (Invitrogen).

↵ 3 The abbreviations used are: HUVEC, human umbilical vein endothelial cell; DiI - Ac - LDL, 1,1 ′ - dioctadecyl - 3,3,3 ′, 3 ′ - tetramethyl - indocarbocyanine acetylated low - density lipoprotein; FACS, fluorescence - activated cell sorting; FGFR, fibroblast growth factor receptor; Flk, fetal liver kinase; ICAM, intercellular adhesion molecule; mAb, monoclonal antibody; PE, phycoerythrin; TNF, tumor necrosis factor; VCAM, vascular cell adhesion molecule.

(HealthDay)-- Elevated fibroblast growth factor 23 (FGF - 23) is associated with increased risk of recurrent major cardiovascular (CV) events in patients after an acute coronary syndrome (ACS), according to a study published...

The experiment shows that β1 - integrin — one of 28 types of integrin — maintains a link between the stem cell and its environment, and interacts biochemically with a growth factor called fibroblast growth factor [FGF] to promote stem cell growth and restoration after muscle tissue injury.

Now Grove and a colleague, reporting in todays Science, have found that Fibroblast Growth Factor 8 (FGF8), whose absence prevents limbs from growing normally, acts as a signal telling the neocortex which way is front.

Expanding from their previous studies with mice, the researchers first established that under specific conditions, culturing human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers for the cerebellar plate neuroepithelium — the part of the developing nervous system specific for the cerebellum — within five.

The research involves a protein called fibroblast growth factor 21 (FGF21), which the scientists previously found helps protect mice against diet - related toxicities to the liver.

When stimulated by molecules called fibroblast growth factors, this receptor, known as FGFR3, prevents the cells from maturing and impedes bone formation.

The researchers hypothesized that these free - floating copies of the receptor would serve as decoys, capturing fibroblast growth factor molecules and reducing stimulation of the cartilage cells» receptors.

Bernard and her co-author Debrup Chakraborty, a postdoctoral student in her lab, studied mice that were fed a high - fat diet and discovered that this higher - risk layer of fat produced larger amounts of the fibroblast growth factor - 2, or FGF2, protein when compared to the subcutaneous fat.

Rivolta and his colleagues knew that during embryonic development, a handful of proteins, including fibroblast growth factor (FGF) 3 and 10, are required for ears to form.

«It's abdominal obesity, and even more specifically, levels of a protein called fibroblast growth factor - 2 that may be a better indicator of the risk of cells becoming cancerous.»

A mutation in the gene encoding fibroblast growth factor receptor 3 (FGFR3) has been associated with two types of skeletal dysplasia, thanatophoric dysplasia (TD), a skeletal dysplasia that cause serious respiratory problems at birth and is often lethal, and achondroplasia (ACH), which causes stunted growth and other complications throughout life.

At the top on the list was a Fibroblast growth factor receptor gene that (Fgfr2) that Carstens had used to identify ESRP1 in earlier research.

In these images of rat brains, differences in gene expression of genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen in rats of two breeds before (left) and after (right) cocaine exposure.