Despite expectations of a rapid breakthrough, no cystic
fibrosis gene therapy trial so far has been able to show long - term clinical improvement.
Not exact matches
Regulators in the US could soon be asked to approve a human
trial of
gene therapy for cystic
fibrosis that uses a hybrid of the HIV and Ebola viruses.
«First
trial of
gene therapy for cystic
fibrosis to show beneficial effect on lung function.»
A
therapy that replaces the faulty
gene responsible for cystic
fibrosis in patients» lungs has produced encouraging results in a major UK
trial.
One early success story is cystic
fibrosis: since the
gene was identified in 1989, exceptional progress has been made in devising new experimental treatments, including
gene therapy trials.
There are now more than 100
gene therapy clinical
trials aimed toward cancer, genetic diseases (such as ADA deficiency, cystic
fibrosis and hemophilia A), infectious diseases (including AIDS) and autoimmune diseases (such as rheumatoid arthritis).
WOMEN with cystic
fibrosis are to join British
gene therapy trials for the first time.
The current U.K.
trial is again using fats, or lipids, but the DNA includes a segment called a promoter that should make
gene expression last longer, says Eric Alton of Imperial College London, who heads the UK Cystic Fibrosis Gene Therapy Consort
gene expression last longer, says Eric Alton of Imperial College London, who heads the UK Cystic
Fibrosis Gene Therapy Consort
Gene Therapy Consortium.