Sentences with phrase «fibrosis lung infection»

Bragonzi A, Paroni M, Nonis A, Cramer N, Montanari S, Rejman J, Di Serio C, Döring G, Tümmler B. Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence.

Not exact matches

The Danger: The wipes contain the bacteria Burkholderia cepacia (B. cepacia), and people with weakened immune systems or chronic lung conditions like cystic fibrosis may be more susceptible to infection.

One mystery of cystic fibrosis is why most children suffer chronic and often deadly lung infections from a bug that rarely harms healthy individuals.

«P. aeruginosa biofilm infections are a leading cause of death for people suffering from cystic fibrosis, a genetic condition that affects the lungs and the digestive system,» said Principal Investigator Lars Dietrich, an associate professor of biological sciences.

The bacteria, Burkholderia cenocepacia, are highly antibiotic resistant and cause severe lung infections in people with cystic fibrosis.

One possibility would be to test the virus on people with cystic fibrosis, to see if it can defeat stubborn Pseudomonas lung infections.

In cystic fibrosis, a serious genetic disease that causes recurring lung infections, bacteria colonize a patient's lungs, usually beginning in childhood, leading to difficulty breathing.

The findings help explain why lung infections in cystic fibrosis patients are so hard to treat.

Although scientists first mapped the genetic structure of P. aeruginosa 15 years ago, efforts to pinpoint how it behaves during an infection and which genes would need to be turned off to stop its spread have been hampered in part by the difficulty of mimicking the unique conditions of a cystic fibrosis patient's lungs.

Once limited to burn wounds, P. aeruginosa now causes severe hospital - acquired infections and persistent lung infections in cystic fibrosis patients.

This leads to recurrent life - threatening lung infections, which result in lung damage that causes 90 % of deaths in people with cystic fibrosis.

People with cystic fibrosis can get Pseudomonas aeruginosa infections in their lungs, which can lead to fatal pneumonia.

Most people with cystic fibrosis develop lung infections that involve multiple species of microbes.

Dental plaque may be the best - known example of a biofilm, but these slimy aggregates of bacteria also play major roles in such chronic infections as those in the urinary tract or in the lungs in cystic fibrosis patients.

«As a result of studying these proteins, we discovered novel structures that turn out to work very well against bacterial infections, including the complicated bacterial populations in lung infections in cystic fibrosis patients.»

«Infections with progressively resistant bacteria in the lung shorten the lives of people with cystic fibrosis,» said Joseph M. Pilewski, M.D., co-director of the Adult Cystic Fibrosis Center fibrosis,» said Joseph M. Pilewski, M.D., co-director of the Adult Cystic Fibrosis Center Fibrosis Center at UPMC.

It is especially promising in the development of a potential treatment for lung infections in people with cystic fibrosis.

The first of many probable applications will likely be the chronic bacterial infections in the lungs of cystic fibrosis patients «that frequently develop resistance to all standard antibiotics, and are the leading cause of death in these patients,» says senior author Ronald Montelaro.

They announced that they had used exome sequencing to identify people with cystic fibrosis who are at high risk of infection with the bacterium Pseudomonas aeruginosa — associated with worse lung health and survival (Nature Genetics, DOI: 10.1038 / ng.2344).

It might be possible, Schonwetter speculates, to develop aerosols containing an LAP - like antiseptic that could be inhaled by cystic fibrosis sufferers to help them fight off lung infections.

Laura and Cate are among thousands of Americans who have cystic fibrosis (CF), an inherited disease that clogs the lungs with thick mucus, encouraging chronic infections that eventually kill.

Malnutrition and lung infections are associated with increased risk of death in people with cystic fibrosis, so better nutrition and minimizing hospitalizations due to infections are important to further improve survival in CF.

Infections with these organisms in patients with chronic lung diseases like cystic fibrosis represent an enormous challenge in medical therapy.

Researchers have identified two new biological markers of cystic fibrosis (CF), a genetic disease which affects children and young adults, leaving them with lifelong health complications including digestive problems and persistent lung infections.

For example, specially targeted phages have been suggested as a possible therapy for conditions like cystic fibrosis, which is caused by frequent bacterial lung infections.

People with cystic fibrosis frequently have lung infections that defy treatment.

While the life expectancy for children with cystic fibrosis has increased over the past few decades, many lives are still shortened in young adulthood by the ravages of lung infections.

Bragonzi A. Murine models of acute and chronic lung infection with cystic fibrosis pathogens.

Rhinovirus C infections are also a major contributor to poor outcomes for people with chronic lung conditions like cystic fibrosis, and early exposure to the virus can cause lifelong lung scarring leading to persistent respiratory difficulties later, says Palmenberg.

A new study shows that tumor suppressor PTEN helps fight lung infections when attached to a protein that is mutated in cystic fibrosis.

It could offer major benefits to cystic fibrosis patients with fungal infections in their lungs.»

In the elderly, lung injury from inhaled particles or from infections might lead to undue scarring processes, some of which in turn lead to lung fibrosis and respiratory insufficiency.

People who have cystic fibrosis are susceptible to bacterial infections in their lungs.

CHAPEL HILL, NC — Cystic fibrosis (CF) shortens life by making the lungs prone to repeated bacterial infections and associated inflammation.

Some patients also develop scarring or fibrosis at the top of the lungs, thus making it harder to ward off viruses and infections.