Sentences with phrase «fibrotic heart»

Rape seed is unsuited to human consumption because it contains a very - long - chain fatty acid called erucic acid, which under some circumstances is associated with fibrotic heart lesions.

High levels of heart disease are associated with selenium - deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China.

Not exact matches

The firm dropped discovery and development in the areas of diabetes, virology, and neuroscience in favor of a research focus on oncology, heart failure, genetically defined diseases, immunoscience, and fibrotic diseases.

The problem arises in this case from a faulty fibrotic conversion and enlargement of the heart.

Fibrotic diseases, such as chronic kidney disease and failure, lung disease, heart failure and cirrhosis of the liver, are estimated to be responsible for up to 45 percent of deaths in the developed world.

In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with human clinical trials expected to begin in 2019.

«Our data are a strong proof of principle and the first to show that inhibiting fibronectin polymerization preserves heart function, reduces left ventricle remodeling and limits formation of fibrotic connective tissue,» said lead investigator of the study and director of translational research in the Heart Institute and the Center for Translational Fibrosis Reseheart function, reduces left ventricle remodeling and limits formation of fibrotic connective tissue,» said lead investigator of the study and director of translational research in the Heart Institute and the Center for Translational Fibrosis ReseHeart Institute and the Center for Translational Fibrosis Research.

In this way, they can mimic the fibrotic changes characteristic of a heart attack and those characteristic of hypertension.

One study of Chinese children consuming rapeseed oil indicated an association with Keshan's disease, which causes fibrotic lesions on the heart (2).

Unfortunately, about two - thirds of the mono - unsaturated fatty acids in rapeseed oil are erucic acid, a 22 - carbon monounsaturated fatty acid that had been associated with Keshan's disease, characterized by fibrotic lesions of the heart.

In areas where there is a selenium deficiency, use of rapeseed oil has been associated with a high incidence of fibrotic lesions of the heart, called Keshan's disease.20 The animal studies carried out over the past twenty years suggest that when rapeseed oil is used in impoverished human diets, without adequately saturated fats from ghee, coconut oil or lard, then the deleterious effects are magnified.