Researchers
find blood markers of incurable neurological disorder years before symptoms appear
I found my blood markers a good indicator of the power of a high - fat, low - carb diet to, at least in my case, improve HDL cholesterol and lower triglycerides, fasting insulin and fasting glucose levels.
Not exact matches
A paper published a year ago in the Journal of Psychiatric Research
found elevated levels of c - reactive protein, a
blood - based
marker of inflammation (which I wrote about two weeks ago) in survivors of the World Trade Center attack; the more traumatic the experience, the higher the CRP.
«Vitamin D
blood test may one day speed bipolar diagnosis in kids:
Finding a reliable
blood marker could offer help to doctors and parents, study suggests.»
Researchers from several institutions, including, UCLA, Boston University, Stanford University and the Institute for Aging Research at Hebrew SeniorLife, analyzed
blood samples from nearly 10,000 people to
find that genetic
markers in the gene responsible for keeping telomeres (tips of chromosomes) youthfully longer, did not translate into a younger biologic age as measured by changes in proteins coating the DNA.
Several researchers, however, are tracking chemical
markers in the
blood and in the breath with the goal of creating screening tools that could someday not just
find cancer but also indicate how dangerous it is likely to be.
At a 0.2 - millimolar sucralose dose similar to the concentration
found in the
blood of people with high consumption of low - calorie sweeteners — equal to four cans of diet soda per day — the researchers said they observed increased expression of genes that are
markers of fat production and inflammation.
Although tau imaging is still in its earliest stages, Ryan hopes that such imaging will accelerate drug development and that
finding a
blood - based biomarker for Alzheimer's to reveal risk (much like cholesterol serves as a
marker for cardiovascular risk) will change the field dramatically in terms of how doctors can diagnose the disease.
We reasoned that the lab would first look for Y chromosome
markers in the
blood, and fail to
find them.
Researchers
found less evidence for the formation of new
blood vessels and fewer protein
markers that signal neuroplasticity, or the brain's ability to make new connections between neurons.
Now, Thomas Jefferson University researchers have
found that a different
blood - sugar
marker is able to predict patients — both diabetic and non-diabetic - with highest risk of complications more accurately, and detect changes in glucose control much faster, which could potentially change clinical practice.
Previous studies have connected high levels of inflammatory
markers in the
blood to bone loss and to fractures in older women and men, which prompted Orchard and her colleagues to wonder what they'd
find if they took one more step back — to the dietary choices that contribute to inflammation in the body.
The study also
found distinct
blood pressure patterns from ages 18 to 55 that reveal people at high risk for calcification of coronary arteries — a
marker for heart disease — by middle age.
Researchers
found expectant mothers with PCOS had significantly higher
markers of inflammation, including white
blood cell counts and C - reactive protein.
But it goes way beyond the old idea of
finding telltale biochemical
markers in
blood or urine.
The researchers
found that the plasmalemma vesicle - associated protein (PLVAP), often used as a
marker for
blood vessels, is expressed in lymph nodes not only in the
blood vessels but also in the lymphatic vessels that transport tissue fluids.
Also, the red
blood cell provides a simple platform for researchers to
find health
markers that are related to a drug's side effects.
To
find out if this was true, workers in stem - cell biologist Irving Weissman's lab at Stanford University Medical School took one
blood stem cell from an adult mouse and tagged it with a
marker that glowed green under fluorescent light.
An association between inflammation biomarkers in both
blood plasma and cerebrospinal fluid (CSF) and
markers of Alzheimer's disease (AD) associated pathology, has been
found by researchers at the University of Colorado Anschutz Medical Campus working with the University of Wisconsin Alzheimer's Disease Research Center and the University of California San Francisco Memory and Aging Center.
The research, published in PLOS ONE,
found that several
markers of insulin resistance were increased following sustained exposure (6 - 8 weeks) to hypoxia at high altitude and that this change was related to increased
blood levels of
markers of inflammation and oxidative stress.
«Our study looked at data over a five - year period and
found elevated levels of two brain injury
markers in the
blood; now the question is whether they may signify permanent traumatic brain injury with long - term consequences.»
The answer was yes: They
found cells with
markers from all three major body cell types, called germ layers: ectoderm (such as nerve cells), mesoderm (muscle and
blood vessel cells), and endoderm (kidney cells).
The study published in Pediatrics also analyzed cardiovascular risk
markers like cholesterol or
blood pressure but
found no consistent differences between southern and central - northern European adolescents.
Additionally, cells expressing MSC
markers were
found to localize to
blood vessel walls in human bone marrow and dental pulp.
These
markers can be used to deconvolute the DNA
found freely in the
blood into tumor DNA and non-tumor DNA.»
Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in
blood vessel output power and significant increase in
blood vessel ageing level and remaining
blood volume 25 minutes later, as
markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and
found adverse histopathological effects on brain cells.96
«The study, which was published in the European Journal of Sports Science,
found that when
blood was measured, the
markers that indicated oxidative stress were
found to actually be higher in those taking the vitamin C.» Though it is not clear why, it is yet more proof that we don't really understand how supplements may work differently to food in our bodies, nor are we really across the many different lifestyle impacts supplements may have on everything from sleep and stress to exercise.
It also appeared to lower levels of a
marker of inflammation
found in the
blood of people with Alzheimer's (called high - sensitivity c - reactive protein)-- although it had no effect on other biomarkers of cell damage or inflammation.
Intermittent fasting appears to help with that, at least it has for me (my
blood markers of insulin resistance have improved, although I haven't gotten a «gold standard» test, as I can't
find where I can get one done).
Of these, several have reported post-treatment reductions in total cholesterol 12, 53, triglyceride 12, 53 and increases in high density lipoprotein (HDL) cholesterol.20 In studies using normotensive rats, three to six months of IER has been observed to lower
blood pressure 16 - 19 and heart rate 16, 17, 19, with the magnitude of the change comparable to CER (40 % ER / day) rats.19 In accordance with these
findings areimprovements in aortic endothelium - dependent and heart rate variability (a
marker of sympatho - vagal balance) in IER - fed rats.72
Common
markers that help identify a PCOS diagnosis along with symptoms and other
findings include a fasting
blood sugar over 100 on a
blood test, and elevated triglycerides and cholesterol (especially if triglycerides are higher than cholesterol).
It
found a strong link between higher levels of chronic inflammation (as measured by
blood levels of an inflammatory
marker) and a decreased likelihood of «successful aging,» defined as optimal physical and cognitive health and the absence of chronic diseases.
Lower inflammatory
blood markers were also
found but, to be fair, some of the improvements in arthritis scores were not much different vs. placebo.
Some studies have
found that low - carb diet may improve some metabolic
markers, such as insulin sensitivity and
blood lipids, but many studies have also confirmed that these diets do nothing to lower your risk of CVD.
Genes have been
found to regulate lipid and cholesterol metabolism, while metabolic
markers, such as
blood sugar and insulin, are already cemented in science.
The study
found athletes had significantly lower
blood lactate levels and plasma creatine kinase levels (this is a
marker of protein regulation and overtraining).
A study published in the July 2012 issue of the journal «Current Sports Medicine Reports»
found that resistance exercise, such as weight lifting, improves
blood sugar control by improving insulin sensitivity and decreasing levels of hemoglobin A1c, or HbA1c, a
blood marker that reflects
blood sugar levels for three months prior to the
blood test.
Studies have shown that raspberry extract can help prevent arthritis; and that blueberries can help protect against intestinal inflammation and even ulcerative colitis; and that those who eat more strawberries have lower levels of C - Reactive Protein, an inflammatory
marker found in the
blood.
In fact, one study
found that glutamine or glutamine plus carbohydrates can help reduce a
blood marker of fatigue during two hours of running (33).
Another study
found that providing the water to rats with diabetes led to improvements in
blood sugar levels and reductions in
markers of oxidative stress, including malondialdehyde (MDA)(10).
Inverse relation of dietary protein
markers with
blood pressure:
findings for 10 020 men and women in the INTERSALT study.
Many studies
found dramatic improvements in
blood sugar levels, weight and other
markers when carbs were restricted to 20 grams per day.
In fact, a study out last week
found that oat consumption doesn't just help lower LDL (bad) cholesterol levels, but that it also brings down two other
markers of cardiovascular risk — non-HDL cholesterol (total cholesterol minus HDL) and apolipoprotein B, a protein that carries bad cholesterol through the
blood.
The good news is that if
markers for these tubal cells can be
found, then
blood tests, advanced Pap smears, or direct tests on tubal tissue might spot ovarian cancer earlier, the study authors said.
Research is being conducted to
find a genetic
marker for the disease so that in the future, a
blood test can diagnose carriers.
The study looked at the link between BMI and health
markers including
blood pressure and cholesterol and
found that 34.4 million people considered overweight and 19.8 million considered obese are actually healthy based on these other measures.