The tests are based on research conducted by Columbia University Irving Medical Center (CUIMC) investigators — and could pave the way for a more precise approach to cancer therapy and help
find effective drugs when conventional approaches to precision medicine have failed.
«We need to do everything we can to
find effective drugs against the Zika virus, as changes in travel and climate have caused more tropical diseases to move into new parts of the globe,» said Kao, who has also spent 15 years studying the virus that causes hepatitis C.
According to Dr. Raül Andero Galí, lead researcher in this study, «Once we discovered the relationship between the Ppm1f gene and different psychological disorders after exposure to traumatic stress, we wanted to
find an effective drug to prevent these changes and its negative consequences on the brain.»
«We thought they'd realize we've
found an effective drug for treating an underserved group with a high mortality rate from heart disease,» Cohn says.
Not exact matches
A small 2006 study
found ginkgo was as
effective as the
drug donepezil for boosting attention and memory in people with mild to moderate Alzheimer's.
Last week, IBM announced that many of its U.S. workers who have cancer will be able to use the supercomputer to
find the most
effective drugs beginning in 2017.
Beginning in January 2017, IBM employees in the U.S. will be able to use Watson supercomputer technology to help
find the most
effective oncology
drugs and clinical trials for their specific cancers, IBM announced.
The
drug may soon
find a wider market if it can be shown
effective in treating lymphoma and other blood cancers, and the price for those indications may well be different, based on their if value story.
And Valeant's round - about method of funding research, if that's what it's actually doing, seems a lot less cost
effective, with all of the bankers and lawyers and hedge fund managers taking chunks of deals than if
drug companies directly devoted a portion of their sales toward
finding new
drugs.
I
find it funny that these religious organizations buy hospitals and use what
drugs scientist have deemed
effective.
A 2005 study in the American Journal of Clinical Nutrition
found that consuming almonds as part of a heart - healthy diet can be just as
effective at lowering LDL «bad» cholesterol levels as first generation statin
drugs.
By accelerating promising
drug candidates through the
drug discovery and development pipeline and spearheading innovative public - private partnerships, we increase the chance of
finding an
effective treatment, and a cure, for Alzheimer's disease.
Charlotte's family tried to help her with pharmaceutical
drugs, but
found they were only
effective for so long before the seizures would come back, hundreds per week.
The FDA has not approved these
drugs for children under a year old because no studies have
found them
effective in that population.
Given the variety of strains and ways to take in the
drug, patients could
find marijuana more
effective for their health conditions at one dispensary rather than another.
«So we will develop diversionary programmes to take users out of the criminal justice system altogether, ensure that those who need treatment get it, and
find more
effective ways to reduce or end their
drug use.
To be
effective and reduce recurrence of cancer in the prostate, researchers
found that prescribing PARP inhibitors, a
drug commonly used in breast cancer, alongside anti-hormone therapy treatment may benefit men with prostate cancer.
«In fact, very little progress in
finding more
effective drugs for epilepsy has been made in the past 100 years.»
«If
drugs are proved not to be
effective or to have some bad effects, [there may be] pressure not to publish these
findings at all,» Anderson says.
Mitchell Cohen, a microbiologist at the Centers for Disease Control and Prevention, in Atlanta, says that although he
finds the EGS approach to
drug resistance «very clever,» in the long run, it may be no more
effective than another new antibiotic.
Ubogu says the
findings are very exciting, as they provide knowledge of leukocyte trafficking in human nerves, but more work needs to be done in affected patients to develop an
effective drug.
University of Melbourne Professor, Leann Tilley, an Australian Research Council Laureate Fellow at the Bio21 Institute, tested the new
drug in red blood cells infected with parasites and
found that it was as
effective at killing the artemisinin resistant parasites as it was for the sensitive parasites.
«All we had to do was
find a
drug that was safe and
effective in alleviating the type of pain that we're interested in.»
As a result, infectious disease experts currently try to
find a balance between making sure
drugs are
effective at knocking out harmful bacteria while keeping the treatment duration to the bare minimum required to stamp out an infection.
Not all chemotherapy
drugs are equally
effective for all people, and
finding the best treatment for an individual is a painful process of trial and error that wastes time and exposes patients to toxic side effects.
Although there is no cure for SMA currently, the National Institutes of Health (NIH) has listed SMA as the neurological disease closest to
finding a cure, due in part to
effective drugs like the one developed in Lorson's lab.
Canada's program that aims to prevent pregnancy in women who use the powerful acne
drug isotretinoin (Accutane) is not
effective,
found a new study in CMAJ (Canadian Medical Association Journal).
«We
found that the protein isoforms expressed in African Americans with prostate cancer do not always respond to targeted therapies, whereas these
drugs were
found to be
effective in European Americans with prostate cancer and do end up killing off the cancer,» said Lee.
Earlier this month, a network of researchers supported by the National Eye Institute (NEI)
found that the
drug Lucentis (ranibizumab) can be highly
effective for treating proliferative diabetic retinopathy, an eye disease that can occur as a complication of diabetes.
«Genes may cause tumor aggressiveness,
drug resistance in African - American prostate cancer: Research
found many targeted therapies for prostate cancer may not be
effective against tumors in African - American men.»
We're unlikely to invent
effective smart
drugs, but you can do more with what you have — by
finding effective ways to work smarter, for one thing
For example, a study just out in The Lancet, funded by the U.S. Food and
Drug Administration and focused on Medicare patients,
found that the high - dose vaccine was 22 percent more
effective at preventing flu - related hospital admissions.
«I doubt a single
drug will ever work in this cancer, so it is a matter of
finding which
drugs in combination are going to be most
effective,» says Dr. Smallridge.
Among the three -
drug combinations, the researchers
found two that were noticeably more
effective than they had expected.
Even if a pigmentation - stimulating
drug is
found to be safe and
effective in people, it would likely not be a substitute for sunscreen, Fisher says.
The
finding, reported in July, shifts the focus of depression's source from neuron function to metabolism, which could lead to more
effective diagnosis and
drug treatments, Flint says.
Drug classes
found to meet «Level A» criteria in the study (established as
effective for treating acute migraine) included triptans, dihydroergotamine (DHE), many NSAIDS (nonsteroidal anti-inflammatory
drugs), butorphanol nasal spray, and the combination medications sumatriptan / naproxen and acetaminophen / aspirin / caffeine.
«These
findings are important for cancer treatments, as currently there are no
drug therapies for enchondromas and there are no universally
effective chemotherapies for chondrosarcomas,» said senior author Benjamin Alman, M.D., chair of the Orthopaedic Surgery Department at Duke University Medical Center.
«Unsuspected characteristics of new cystic fibrosis
drugs found, offering potential paths to more
effective therapies.»
«One criticism of the PARP
drugs is they are not active in patients who have developed resistance to other therapies, but we
found veliparib appears to be
effective in some platinum - resistant patients with recurrent or persistent disease,» said Robert L. Coleman, MD, lead author of the study and professor and vice chair of clinical research at the University of Texas MD Anderson Cancer Center, Houston.
The immunotherapy
drug pembrolizumab — already FDA - approved for other forms of cancer - has been
found to be
effective in patients with metastatic triple negative breast cancer, according to an international clinical trial led by NYU Langone's Perlmutter Cancer Center.
After further screening, three
drugs, trifluoperazine, an antipsychotic, doxapram, a breathing stimulant, and amoxapine, an anti-depressant, were used in a mouse model and were
found to be
effective in treating plague.
Nevertheless, he says, the
finding suggests that
drugs that block the cell - division pathway will be an
effective treatment for NF - related leukemia and potentially for other disease complications.
«Our research also shows that existing
drugs can be repurposed to treat other diseases and once several potential
drugs are
found, we can redesign them to be more
effective in combating their targeted diseases while reducing the side effects.»
If the
findings hold up in people, researchers may have
found a way to treat a large swath of tumors that has lacked
effective drugs.
«For example, we
found that highly aggressive ovarian cancer cells are glutamine - dependent, and in our laboratory studies, we showed that depriving such cells of external sources of glutamine — as some experimental
drugs do — was an
effective way to kill late - stage cells.
Herceptin was an «astonishingly
effective... wonder
drug», enthused the media, while doctors talked of «revolutionary», «stunning», «jaw - dropping»
findings.
By performing experiments in petri dishes and with mice, they
found that panobinostat, a
drug designed to change the way cells regulate genes, may be
effective at inhibiting DIPG growth and extending survival rates.
A review of studies on the treatment of chronic insomnia
finds that cognitive behavioral therapy is an
effective alternative to
drug interventions
Given the progressive nature of MS, the debilitating nature of fatigue, and the lack of
effective fatigue
drug treatments that work for the majority, such
findings are encouraging and important.