Sentences with phrase «find novel therapies»

Gladstone was a great fit for me, especially with its background in developmental and translational biology and Bruce's research focus on cutting - edge technologies to model genetic disease and find novel therapies for treating them.

Not exact matches

Lindquist was starting a biotech company called FoldRx Pharmaceuticals Inc., which partly relied on Outeiro's findings to develop novel therapies for protein - misfolding diseases.

The findings may not only lead to a novel diagnosis tool of PSC, they may also be the starting point for developing microbiota - based therapies.

A novel psychological therapy that encourages addressing emotional experiences related to trauma, conflict and relationship problems has been found helpful for people with the chronic pain condition fibromyalgia.

«Our highly novel findings offer the potential to develop personalised approaches therapy.

While the findings suggest that drugs targeting ASICs may one day lead to novel therapies for anxiety disorders, Braga noted that «more research is needed to understand the roles that ASIC1a channels play in the brain.»

«We are excited that our translational research team of clinicians and basic researchers have come together to present these novel findings and hope that future studies and trials based on this work can move forward to bring targeted therapies for TED,» commented Dr. Phipps.

Still, many in the field are calling the work a major breakthrough, and say the findings could point to new therapies, as well as a novel mechanism for neurodegeneration.

Although the findings are promising, Fornai cautions that «it will take some time to establish whether the use of lithium should be considered as a novel therapy for ALS.»

The findings hold promise for the development of novel targeted therapies with fewer harmful side effects.

Margaret Shupnik, PhD, a Professor of Medicine at UVA's School of Medicine who also worked with Jarjour's team says she hopes that the findings will prompt other researchers to develop novel therapies that regulate TLRs, and offer lupus patients the kind of treatment options that they currently don't have.

With this novel approach, the researchers found that the therapy reduced the virus in the brain, preventing harm to nerve cells.

Findings of a three - year clinical trial led by University of Cincinnati (UC) transplant researchers suggest that a novel pre-operative drug therapy reduces antibodies in kidney patients with greater success than with traditional methods, with the potential to increase the patients» candidacy for kidney transplantation and decrease the likelihood of organ rejection.

The second branch of the combination therapy, the low - dose metronomic chemotherapy, was similarly found to exert its therapeutic effect through a novel, hitherto unrecognized mechanism: The metronomic chemotherapy turned out to not primarily target the tumor cells, but to act on the recruitment of yet another tumor - promoting cell population from the bone marrow.

Young and his colleagues found that twice - weekly infusions of this novel therapy were well tolerated and resulted in a low incidence of bleeding events in children with severe hemophilia A.

The findings point toward novel cholestasis therapies that stop the excessive division that leaves powerhouses in dysfunctional tatters.

An international team of hematologists including Guy Young, MD, of Children's Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a novel therapy called emicizumab, decreases incidence of bleeding episodes by 87 %.

Our findings may prove useful in the development of novel therapies to efficiently reactivate latent HIV - 1, thus making it susceptible to current drug therapies.

In partnership with the Italian Cystic Fibrosis Research Foundation, we founded a CF animal Core Facility (CFaCore) as a platform for pre-clinical studies and for testing novel antibacterial or anti-inflammatory therapies.

Their findings, to be published in the July issue of the journal Cancer Cell, could explain why some tumors don't respond to radiation or chemotherapy, and provide novel routes for the development of new anti-cancer therapies.

A physician with a longstanding interest in gene therapy, Dr. High was formerly a Professor at the Perelman School of Medicine of the University of Pennsylvania, an Investigator of the Howard Hughes Medical Institute, and the Founding Director of the Center for Cellular and Molecular Therapeutics at The Children's Hospital of Philadelphia, a Center focused on developing novel cell and gene - based therapies for genetic disease.

In addition, the FDA will continue to work closely with industry to find other ways to aid in the effort to bring novel therapies to patients as quickly, and as safely, as possible.

«The region - specific cells we found could provide tremendous advantages in the laboratory to study development, evolution and disease, and may offer avenues for generating novel therapies,» says Salk Professor Juan Carlos Izpisua Belmonte, senior author of the paper and holder of Salk's Roger Guillemin Chair.

From founding one of the world's most successful high frequency trading organizations to advancing the power of stem cell therapies and regenerative medicine, Dr. Bosarge combines inventiveness with creative talent to bring novel ideas and products to the marketplace.

Founded in 2014, ImmunXperts provides immunogenicity and immune - oncology screening services, assessing all aspects of the immune responses in donors and patients, supporting its partners in the full development cycle of novel drugs, biotherapeutics and stem cell therapies.

Thus, current efforts have focused on finding novel targets to improve cytotoxic T cell activity that will augment existing therapies.

Format: Publication Years Covered: Cumulative to 2013 Search Strategy: Searched publications to find trials Project Focus: Cord Blood trials, «novel» therapy, status Open, registered anywhere

Format: Publication Years Covered: Cumulative to June 2016 Search Strategy: Searched publications to find trials Project Focus: Cord Blood trials, «novel» therapy, registered anywhere

With her recent groundbreaking findings in the field of RNA - mediated regulation based on the CRISPR - Cas9 system, E. Charpentier has laid the foundation for the development of a novel, highly versatile and specific genome editing technology that is revolutionizing life sciences research and could open up whole new opportunities in biomedical gene therapies.

Format: Publication Years Covered: 1992 - 2012 Search Strategy: Manually search registries by keywords Project Focus: Two Decades review of the world Special Notes: Found 4749 cell therapy trials total, but only 1058 are «novel» therapy

«She will be instrumental in enhancing our ability to develop novel therapies for pediatric diseases by building a framework that translates clinical studies and research findings into daily practices.»

The present studies provide multiple novel findings relevant to the development of astrocyte transplantation therapies for treatment of the injured or diseased central nervous system.

«These findings provide hope that long - term improvements in glucose control may alter the course of kidney disease in people with type 1 diabetes,» said JDRF program director Helen Nickerson, Ph.D. «This reinforces the importance of improved glycemic control as we pursue novel therapies to slow or reverse loss of kidney function.»

These findings suggest that specific MFN2 mutations cause tissue - selective mitochondrial dysfunction with increased adipocyte proliferation and survival, confirm a novel form of excess adiposity with paradoxical suppression of leptin expression, and suggest potential targeted therapies.

«Our findings suggest further investigation into the potential of MC1R - activating agents as novel neuroprotective therapies for PD, and together with epidemiological evidence, may offer information that could guide those carrying MC1R variants to seek advice from dermatologists or neurologists about their personal risk for melanoma and Parkinson's disease,» lead author Xiqun Chen says in a statement.

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Animal Cancer Foundation is a 501 (c)(3) organization dedicated to finding novel treatment therapies and eventual cures for cancer by funding research in and increasing public awareness of comparative oncology, the study of naturally occurring cancers in pets and people to benefit both.

The Michael White workshop in 1987 outlines a few novel letter writing approaches when we find ourselves working with youth who won't come to therapy