Sentences with phrase «find small molecule inhibitors»
In more current, but not yet published work, Sattler is also fusing NMR and crystallography in a drug discovery project to find small molecule inhibitors that neutralize trypanosoma, parasites that cause sleeping sickness, by disrupting life - critical protein - protein interactions.
https://sbgrid.org/ Not exact matches
The authors also found that a novel small molecule inhibitor of the salvage pathway enzyme deoxycytidine kinase blocked leukemia growth in mice in combination with thymidine (to inhibit the de novo pathway).
Founded in 2015, STORM Therapeutics is a British - based developer of small - molecule inhibitors of RNA - modifying enzymes for the treatment of cancer.
Other mutations commonly found in mucosal melanoma have the potential to be targeted by small - molecule inhibitors.
«Scientists can now, at the click of a button and at a single online location, rapidly identify the biological and structural characteristics of an actual or potential drug target, find the genes and proteins that it interacts with, assess its structural druggability and identify any small molecule chemical inhibitors.
This preclinical work led to the development of a novel anti-androgen ARN - 509, a small - molecule inhibitor discovered in collaboration with UCLA chemist Michael Jung, which targets the increased levels of androgen receptor found in hormone - refractory disease.