Sentences with phrase «finding gene families»

Published in GigaScience, the open source Galaxy workflow allows researchers to make easier work of finding gene families; an important tool when it comes to analysing the evolution, structure and function of genes across species.

Easy workflow to find gene families.»

Not exact matches

These findings could explain why twin studies show that ho - mose - xuality runs in families, but no «gay gene» can be found, Rice said.

These findings could explain why twin studies show that homosexuality runs in families, but no «gay gene» can be found, Rice said.

Both kids have had their work selected for the town art show and I am glad the art gene has found a way to my family.

The team found 37 genes that predicted whether family members inherited synesthesia.

Of note, these gene families were most commonly found to have specific protein features gained from their eukaryotic hosts.

The gene aquaporin - 1 encodes channel - forming integral protein (CHIP), a member of a large family of water transporters found throughout nature.

The study found that in the 18th and 19th centuries, about four to 18 per cent of the variation between individuals in lifespan, family size and ages at first and last birth was influenced by genes, while the rest of the variation was driven by differences in various aspects of their environment.

An apparently new Variant of human serum albumin, albumin Naskapi, has been found in high frequency in the Naskapi Indians of Quebec and, in lower frequency, in other North American Indians.The family and population data of the albumin are consistent with its inheritance as a simple autosomal trait Controlled by a gene designated Al Naskapi.

«We found that interbreeding with archaic humans — the Neanderthals and Denisovans — has influenced the genetic diversity in present - day genomes at three innate immunity genes belonging to the human Toll - like - receptor family,» says Janet Kelso of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.

«For 20 years we've been looking for the gene and mutation behind my family's neuropathy, but we never found the variant,» he says.

Together, the researchers focused on a family of genes that encode taste receptors found in fruit flies.

A Canadian project called FORGE (finding of rare disease genes) aims to sequence children and families with 200 different disorders this year.

If they could find an affected gene in the boy's family, it might lead researchers to the causes of more common, sporadic cases of Beckwith - Wiedemann, too.

The two studies together suggest that single copies of inactivating ANGPTL3 mutations are found in roughly one of every 250 people of European descent, whereas people with mutations in both copies of the gene — as in the family studied by Musunuru and colleagues — are much rarer.

Affected family members, the group found, had inherited one or two defective copies of ZIC3, a previously unknown gene that appears to code for a transcription factor — a protein that switches other genes on or off.

Most cases of familial hypolipidemia are linked to other gene mutations that cause liver and digestive problems, but in members of this American family with the condition, Musunuru found mutations in the gene for ANGPTL3, and no associated health problems.

«Mutations responsible for cleft palate and related birth defects identified: Study of Amish and Saudi Arabian families finds mutations in HYAL2 gene that impact development.»

But in a closer study of 73 families researchers found a region of genes on chromosome eight in those with perfect pitch and from European ancestry.

The researchers also found that wtf4 is a member of a large family of selfish genes, and that at least one other wtf gene also causes meiotic drive, suggesting that the family proliferated due to meiotic drive.

Nine rare, disease - causing mutations of the gene, FBXL4, were found in nine affected children in seven families, including three siblings from the same family.

Eight additional affected children in six unrelated families were found to also have disease - causing mutations in this gene.

They found genes for five new receptors, all of which belong to a known family of proteins called formyl peptide receptors (FPRs).

Until now, de novo genetic mutations, alterations in a gene found for the first time in one family member, were believed to be mainly the result of new mutations in the sperm or eggs (germline) of one of the parents and passed on to their child.

In a remote Turkish village, researchers have located a family with a mutation in the leptin gene similar to the one found in lab mice, and — just like the mice — adults with two copies of the mutation are grossly overweight and don't ever go through puberty.

In this week's issue of Nature, the researchers report that they found mutations in the superoxide dismutase genes of 13 families with an inherited form of ALS.

They found a single mutation in the ADGRE2 gene shared by family members with vibratory urticaria but not present in unaffected people.

The study, published in New Phytologist, shows how a gene found in the common fruit fly, Drosophila melanogaster, can be expressed in Arabidopsis, a member of the cabbage family, to improve TNT removal from contaminated soil.

The authors of the paper also found significant changes in the genomic structure and gene families, contradicting the idea of a genuine «living fossil.»

The MHC is a family of genes found in all vertebrates that encodes vital proteins in the immune defense system.

The study of almost 8,000 families, published today (21 March) in Nature, found for the first time that mutations outside of genes can cause rare developmental disorders of the central nervous system.

The protein studied in the mold is part of a larger family of proteins also found in humans and involved in many essential biological processes including gene regulation and fatty acid metabolism.

The study found that 8,600 families of genes are shared across deuterostomes, a large animal grouping that includes a variety of organisms, ranging from acorn worms to star fishes, from frogs to dogs, to humans.

Candida species that often cause disease usually have expansions in these gene families, so given that C. krusei is rarely pathogenic, this finding makes sense.

An alteration in the neuregulin - 1 gene — a single change in one letter of the DNA code for the protein — has been found in families with schizophrenia and linked to late - onset Alzheimer's disease with psychosis.

And when they sequenced Sputnik's genome, they found its small ring of DNA contained genes from three different viral families, including Mamavirus.

A paper they published in the journal Science several months ago has gotten a lot of attention, because after detecting a suspect allele in Finnish families with asthma, the researchers found the same gene in families with asthma in Quebec.

Among those whose relative tested negative for the BRCA1 / 2 gene, but knew the gene was present in their families (meaning they could still carry the gene), only 36 % said they were going to find out their own genetic risk.

C. krusei, they found, has few copies of gene families associated with pathogenesis in C. albicans, including oligopeptide transporters, aspartyl proteases, and phospholipase B genes.

Applying a method for tracing a gene's family tree to the folk tale, Atkinson found that German - speaking Swiss tell the Italian version, not the German one.

The goal now is «to find the subtle genetic differences between individuals in the genes or families of genes associated with longevity,» says Judith Campisi, a senior scientist at the Lawrence Berkeley National Laboratory in California.

For instance, when the researchers removed the possible confounding influence of ApoE4 by looking only at families lacking that ApoE variant, they found that the frequency of the mutant A2M gene in Alzheimer's patients was four times greater than in their siblings who did not have the disease.

The researchers found that over 25 percent of index patients with normal results from commercial testing of BRCA1 and BRCA2, but with families severely affected by breast cancer, could be resolved by sequencing all genes known to be involved in breast cancer.

The researchers found that 18 different genes harbored cancer - predisposing mutations in those 125 families, but each affected person carried a mutation in only one gene.

When it comes to two of the genes on the panel, BRCA1 and BRCA2, there's little doubt that in cancer - prone families, testing saves lives: Extensive study of BRCA carriers has found that those who have their ovaries removed are 80 % less likely to die from ovarian cancer and 50 % less likely to die from breast cancer.

When the team compared E. rubrum's gene families against those in two other halophilic species (Wallemia ichthyophaga and Hortaea werneckii), they found that high acidic residues were common in all three species, a general trait all salt - tolerant microbes share.

Like nearly all genes linked to cancer, BRCA1 and BRCA2 were first found in families riddled with the disease.

A second major finding of the new study, which analyzes the genomes of over 2,500 «simplex» families — those in which a single child but neither parent nor siblings, if any, have ASD — is that the pool of spontaneously mutated genes contributing to ASD across the population totals about 400.

«We have also found a number of gene families that seem to be involved in the parasitism of insects by worms and we are excited to continue studying these in future experiments.»