Sentences with phrase «finding of new genes»

«The Medaka experiment finding of new genes affected by microgravity provides a good animal model to clarify this mechanism.»

Not exact matches

Collaboration based on new findings from the Regeneron Genetics Center ® showing variant in HSD17B13 gene is associated with reduced risk of chronic liver diseases

Mostly they are optimists, excited by the latest findings: the newly isolated gene variant that may help explain schizophrenia, the new telescopic images that reveal the violent births of distant....

On the contrary, he finds it useful to ponder an array of reductionist attempts to explain the existence of religion, from that which seeks to pinpoint the area of the human brain or the specific genes connected to religiosity to that which sees religion as a malfunction of the human mind or a vestigial remnant from a primitive stage of human development suitable only for whimpering, immature dullards (a point of view championed by the new atheists).

«In two studies of breast - fed infants involving more than 3,000 children in Britain and New Zealand, breastfeeding was found to raise intelligence an average of nearly 7 IQ points if the children had a particular version of a gene called FADS2.

And researchers generally shied away from clinical research on any patented genes — a 2003 survey found that 53 percent of genetics labs decided not to develop a new genetic test because of a patent or license.

«But the discovery of this network of genes linked to epilepsy opens avenues for finding new treatments.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

As well as understanding the implications of finding this new variant of the botulism gene cluster in a non-clostridial species of gut bacterium, the team are interested in exploring how it might help in developing new treatments for diseases.

As CRISPR - Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene - editing technology can introduce hundreds of unintended mutations into the genome.

An apparently new Variant of human serum albumin, albumin Naskapi, has been found in high frequency in the Naskapi Indians of Quebec and, in lower frequency, in other North American Indians.The family and population data of the albumin are consistent with its inheritance as a simple autosomal trait Controlled by a gene designated Al Naskapi.

Virgin, an immunologist, said he thinks the new findings will produce a more complicated but also much more insightful picture of how human, bacterial and viral genes influence human health.

«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search for new ways to classify aggressive forms of the disease.»

«Within the context of our emerging appreciation of polygenic risk, where gene variations are implicated in several disorders, the new findings point to only partial overlap in the risk mechanisms for these two forms of bipolar disorder,» said Dr. Krystal.

The findings by a team of Massachusetts General Hospital (MGH) investigators, which will be published in the April 24 issue of Cell and are receiving advance online release, support the importance of epigenetics — processes controlling whether or not genes are expressed — in cancer pathology and identify molecular circuits that may be targeted by new therapeutic approaches.

A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss - of - function mutations to Filaggrin - 2 (FLG2), a gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.

John March of Cornell University in Ithaca, New York and his team took the bacterium Lactobacillus gasseri, which is found in some probiotic yogurts, and equipped it with a human gene for a hormone called glucagon - like peptide - 1.

Perhaps most significantly, in a study led by Frances Champagne — then a graduate student in Meaney's lab, now an associate professor with her own lab at Columbia University in New York — they found that inattentive mothering in rodents causes methylation of the genes for estrogen receptors in the brain.

These differentially expressed microRNAs point the way toward finding more genes associated with glaucoma, more clues about how these glaucoma types each go about damaging our optic nerve and potential new points of intervention, the scientists say.

New research presented here yesterday at the annual meeting of the American Association for the Advancement of Science (which publishes ScienceNOW) finds that a gene associated with increased risk of asthma is also linked to resistance against a parasitic worm.

By examining gene expression patterns, the new study found that parrot brains are structured differently than the brains of songbirds and hummingbirds, which also exhibit vocal learning.

With the advent of new gene editing techniques, some less common animal models such as octopuses may find their way into scientists» toolkits.

More than 80 percent of the viral gene sequences he found were new to science.

The study found several genes that are associated with resistance to antibiotics, including new genes that might point to previously unknown mechanisms of drug resistance.

To find out what BRCA2 does normally, the team reporting the new results, which includes Allan Bradley of Baylor College of Medicine in Houston and Paul Hasty of Lexicon Genetics Inc. in The Woodlands, Texas, created «knockout» mice in which the gene was inactivated.

Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome - wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

The new finding shows that «gene flow across taxonomic boundaries happens,» observes geneticist Michael F. Hammer of the University of Arizona.

In a new study, researchers are taking joint biopsy tissue from patients at the start of a new therapy and then six weeks later to see if they can find a predictor gene sequence that will clearly identify which patients respond to a particular therapy.

The unexpected finding may also spark a new avenue of research on a type of gene regulation known as imprinting.

They found genes for five new receptors, all of which belong to a known family of proteins called formyl peptide receptors (FPRs).

Another found gene is linked to angiogenesis, the production of new blood vessels to support a tumor.

Until now, de novo genetic mutations, alterations in a gene found for the first time in one family member, were believed to be mainly the result of new mutations in the sperm or eggs (germline) of one of the parents and passed on to their child.

Joint lead author Professor Manfred Kayser from Erasmus MC said: «Besides substantially increasing our understanding of human pigmentation genetics in general, finding these new hair colour genes is also important for further increasing the accuracy of hair colour prediction from DNA traces in future forensic applications, which can help to find unknown perpetrators of crime.»

A parallel paper in the same journal by researchers from the University of Liverpool shows that this same gene also caused the peppered moth to turn black during the mid-19th century, when it evolved to find new ways to camouflage itself; a side - effect of industrial pollution at the time.

The new findings suggest a way to stratify the wide range of patients with MDD, which may boost the likelihood of identifying culpable genes.

They knew that they had found a new type of genetic defect, because the DNA in cancer cells from people with the altered gene was riddled with mutations.

«Single gene encourages growth of intestinal stem cells, supporting «niche» cells, and cancer: Finding in mice could lead to new therapies for damaged organs, cancer.»

First author Professor Martin Hrabe de Angelis, Director of Institute of Experimental Genetics at the Helmholtz Zentrum München, who invented the mouse clinic concept, said: «Our findings with regard to the genes examined are now available to the scientific community as a valid data set, which can be downloaded free of charge from the IMPC (International Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can develop and test new hypotheses.»

The Grants had shown that gene flow has occurred in the finches of Daphne Major during the past 40 years, but the new study found extensive evidence for gene flow throughout the roughly 1 million years that the birds have occupied the archipelago, which has helped the researchers update their understanding of how the lineages diverged over time.

Researchers now suspect that this finding will open up a whole new area of medical genetics, with DNA repair genes becoming the prime suspects in causing other cancers and hereditary illnesses.

The three Ras genes found in humans — H - Ras, K - Ras and N - Ras — were among the first to be linked to cancer development, and a new study led by VCU Massey Cancer Center researcher Paul Dent, Ph.D., has shown the recently approved breast cancer drug neratinib can block the function of Ras as well as several other oncogenes through an unexpected process.

Professor Peter Kraft at Harvard TH Chan School of Public Health, USA, says: «Given the size of these studies, we expected that we would find a lot of new breast cancer risk variants, but the studies tells us a lot more about which genes are involved, revealing many previously unsuspected genes and genetic mechanisms underlying breast carcinogenesis.

These new findings appear in Genes and Development, a leading journal in the field of developmental biology.

Shaw reverses the process in a new paper, taking what he finds in humans back to the flies and gaining new insight into humans as a result: identification of a human gene that is more active after sleep deprivation.

Now, Mitchum's team is trying to find how this key gene might work differently in other nematode types, like root - knot nematode as part of a new National Science Foundation grant.

The study, published in New Phytologist, shows how a gene found in the common fruit fly, Drosophila melanogaster, can be expressed in Arabidopsis, a member of the cabbage family, to improve TNT removal from contaminated soil.

«We have already found several gene types that are dramatically expanded in the octopus relative to other vertebrates, and we think they play a critical role allowing a new level of neuronal complexity to be reached in invertebrates,» he said.

A new study led by Boston Children's Hospital and the University of Montreal raises a note of caution, finding that person - to - person genetic differences may undercut the efficacy of the gene editing process or, in more rare cases, cause a potentially dangerous «off target» effect.

In the new study, the team genetically inactivated HIV - 1 in transgenic mice, reducing the RNA expression of viral genes by roughly 60 to 95 percent, confirming their earlier findings.

«The good news is that this finding predicts that patients missing either gene should be sensitive to new therapies targeting focal adhesion enzymes, which are currently being tested in early - stage clinical trials,» says Shaw, who is also a member of the Moores Cancer Center and an adjunct professor at the University of California, San Diego.